ES2088464T3 - Uso y administracion de enzimas. - Google Patents
Uso y administracion de enzimas.Info
- Publication number
- ES2088464T3 ES2088464T3 ES91302397T ES91302397T ES2088464T3 ES 2088464 T3 ES2088464 T3 ES 2088464T3 ES 91302397 T ES91302397 T ES 91302397T ES 91302397 T ES91302397 T ES 91302397T ES 2088464 T3 ES2088464 T3 ES 2088464T3
- Authority
- ES
- Spain
- Prior art keywords
- enzymes
- administration
- target site
- enzyme
- target
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6815—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6883—Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy
- A61K47/6885—Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy the conjugate or the polymer being a starburst, a dendrimer, a cascade
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/94—Involves covalent bonding to the substrate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Genetics & Genomics (AREA)
- Birds (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
UNO O MAS VEHICULOS, QUE PUEDEN SER ACEPTABLES DE ENTRAR EN LA BOCA, CONTIENEN AL MENOS UNO O DOS ENZIMAS COOPERANTES MAS UN ANTICUERPO O FRAGMENTO DE ANTICUERPO QUE SE UNE A UN BLANCO. HAY MEDIOS PARA ATACAR AMBAS ENZIMAS A DICHOS ANTICUERPOS O SUS FRAGMENTOS, PARA ASI UNIR LAS ENZIMAS A LA VECINIDAD DEL BLANCO. UNA ENZIMA GENERA UN INTERMEDIARIO, EL CUAL ES UTILIZADO POR LA OTRA ENZIMA PARA GENERAR UNA SUBSTANCIA, PREFERIBLEMENTE HIPOALITA, QUE ACTUA EN DONDE ESTA EL BLANCO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909006328A GB9006328D0 (en) | 1990-03-21 | 1990-03-21 | Cell killing |
GB909021671A GB9021671D0 (en) | 1990-10-05 | 1990-10-05 | Delivery of agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2088464T3 true ES2088464T3 (es) | 1996-08-16 |
Family
ID=26296815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91302397T Expired - Lifetime ES2088464T3 (es) | 1990-03-21 | 1991-03-20 | Uso y administracion de enzimas. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0450800B1 (es) |
JP (1) | JPH04234821A (es) |
AT (1) | ATE139704T1 (es) |
AU (1) | AU642979B2 (es) |
BR (1) | BR9101118A (es) |
CA (1) | CA2038577C (es) |
DE (1) | DE69120452T2 (es) |
ES (1) | ES2088464T3 (es) |
IN (1) | IN172886B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9021671D0 (en) * | 1990-10-05 | 1990-11-21 | Unilever Plc | Delivery of agents |
AU642980B2 (en) * | 1990-03-21 | 1993-11-04 | Quest International B.V. | Ultilization of enzymes |
US5486360A (en) * | 1993-04-22 | 1996-01-23 | St. Joseph Health Centre | Method of treating tumour cells using catalase |
JP2000503000A (ja) * | 1995-12-21 | 2000-03-14 | クエスト・インターナショナル・ビー・ブイ | 粒状組成物 |
US5972355A (en) * | 1997-09-30 | 1999-10-26 | E-L Management Corp. | Stable compositions containing biologically active components |
US5871714A (en) * | 1997-10-16 | 1999-02-16 | Pharmacal Biotechnologies, Inc. | Compositions for controlling bacterial colonization |
EP1787627A1 (en) | 2005-11-17 | 2007-05-23 | 3M Innovative Properties Company | Anti-microbial dental impression material |
US8663616B2 (en) | 2010-12-20 | 2014-03-04 | E I Du Pont De Nemours And Company | Enzymatic peracid generation for use in oral care products |
CN103261430A (zh) | 2010-12-20 | 2013-08-21 | 纳幕尔杜邦公司 | 靶向过水解酶 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1433593A (en) * | 1972-06-09 | 1976-04-28 | Royal College Of Surgeons | Conjugates |
US4657853A (en) * | 1984-09-14 | 1987-04-14 | E. I. Du Pont De Nemours And Company | Immunoassays utilizing covalent conjugates of polymerized enzyme and antibody |
ES2054678T5 (es) * | 1986-08-18 | 1997-09-16 | Dow Chemical Co | Conjugados estrella. |
US4943525A (en) * | 1987-11-02 | 1990-07-24 | Bioventures, Inc. | Simultaneous immunoassay for the determination of antigens and antibodies |
SE461570B (sv) * | 1988-06-06 | 1990-03-05 | Rama Bio Link Ab | Farmaceutiskt preparat och konjugat av en baktericid och en antikropp |
AU4402589A (en) * | 1988-09-28 | 1990-04-18 | Ideon Corporation | Combination enzyme immunotherapeutics |
-
1991
- 1991-03-18 AU AU72996/91A patent/AU642979B2/en not_active Ceased
- 1991-03-19 CA CA002038577A patent/CA2038577C/en not_active Expired - Fee Related
- 1991-03-20 ES ES91302397T patent/ES2088464T3/es not_active Expired - Lifetime
- 1991-03-20 DE DE69120452T patent/DE69120452T2/de not_active Expired - Fee Related
- 1991-03-20 AT AT91302397T patent/ATE139704T1/de not_active IP Right Cessation
- 1991-03-20 JP JP3130820A patent/JPH04234821A/ja active Pending
- 1991-03-20 EP EP91302397A patent/EP0450800B1/en not_active Expired - Lifetime
- 1991-03-21 BR BR919101118A patent/BR9101118A/pt not_active Application Discontinuation
- 1991-03-21 IN IN84BO1991 patent/IN172886B/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE69120452T2 (de) | 1996-10-31 |
AU7299691A (en) | 1991-10-03 |
DE69120452D1 (de) | 1996-08-01 |
BR9101118A (pt) | 1991-11-05 |
EP0450800A1 (en) | 1991-10-09 |
JPH04234821A (ja) | 1992-08-24 |
EP0450800B1 (en) | 1996-06-26 |
CA2038577C (en) | 2001-06-19 |
ATE139704T1 (de) | 1996-07-15 |
IN172886B (es) | 1993-12-25 |
CA2038577A1 (en) | 1991-09-22 |
AU642979B2 (en) | 1993-11-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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