ES2080114T3 - Procedimiento para preparar un factor inhibidor de la metastasis. - Google Patents
Procedimiento para preparar un factor inhibidor de la metastasis.Info
- Publication number
- ES2080114T3 ES2080114T3 ES90305459T ES90305459T ES2080114T3 ES 2080114 T3 ES2080114 T3 ES 2080114T3 ES 90305459 T ES90305459 T ES 90305459T ES 90305459 T ES90305459 T ES 90305459T ES 2080114 T3 ES2080114 T3 ES 2080114T3
- Authority
- ES
- Spain
- Prior art keywords
- mif
- metastasis
- preparing
- procedure
- inhibiting factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LAS CELULAS HEMATOPOYETICAS HUMANAS PRODUCEN EL FACTOR INHIBITORIO DE LA METASTASIS (MIF). EL MIF PRESENTA UNA NOTABLE ACTIVIDAD INHIBITORIA DE LA METASTASIS EN ENFERMEDADES VIRICAS E INMUNOPATIAS, ASI COMO, EN TUMORES MALIGNOS. LAS CELULAS HEMATOPOYETICAS HUMANAS PRODUCTORAS DEL MIF PROLIFERAN FACILMENTE MEDIANTE CULTIVOS DE TEJIDOS IN VITRO, ESTOS CULTIVOS SE HACEN EN ANIMALES DE SANGRE CALIENTE NO HUMANOS. LAS CELULAS T PRESENTAN UNA ALTA PRODUCCION DE MIF. LOS MITOGENES AUMENTAN LA PRODUCCION DE MIF CUANDO SE USA UN INDUCTOR DE MIF.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1128362A JP2926409B2 (ja) | 1989-05-22 | 1989-05-22 | 癌転移抑制因子の製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2080114T3 true ES2080114T3 (es) | 1996-02-01 |
Family
ID=14982946
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90305459T Expired - Lifetime ES2080114T3 (es) | 1989-05-22 | 1990-05-21 | Procedimiento para preparar un factor inhibidor de la metastasis. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5126148A (es) |
EP (1) | EP0401997B1 (es) |
JP (1) | JP2926409B2 (es) |
KR (1) | KR0157227B1 (es) |
AT (1) | ATE127527T1 (es) |
CA (1) | CA2017279A1 (es) |
DE (1) | DE69022121T2 (es) |
DK (1) | DK0401997T3 (es) |
ES (1) | ES2080114T3 (es) |
GR (1) | GR3018004T3 (es) |
RU (1) | RU2070046C1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3439490B2 (ja) * | 1992-09-28 | 2003-08-25 | 株式会社林原生物化学研究所 | 蛋白質とその蛋白質をコードするdna並びにその蛋白質の製造方法 |
JPH1080270A (ja) * | 1996-07-19 | 1998-03-31 | Hayashibara Biochem Lab Inc | ポリペプチドをプロセッシングする酵素 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4785077A (en) * | 1986-05-05 | 1988-11-15 | Scripps Clinic And Research Foundation | Substantially pure cytotoxicity triggering factor |
-
1989
- 1989-05-22 JP JP1128362A patent/JP2926409B2/ja not_active Expired - Fee Related
-
1990
- 1990-05-21 DK DK90305459.1T patent/DK0401997T3/da active
- 1990-05-21 DE DE69022121T patent/DE69022121T2/de not_active Expired - Fee Related
- 1990-05-21 EP EP90305459A patent/EP0401997B1/en not_active Expired - Lifetime
- 1990-05-21 ES ES90305459T patent/ES2080114T3/es not_active Expired - Lifetime
- 1990-05-21 AT AT90305459T patent/ATE127527T1/de not_active IP Right Cessation
- 1990-05-21 RU SU904830212A patent/RU2070046C1/ru active
- 1990-05-22 CA CA002017279A patent/CA2017279A1/en not_active Abandoned
- 1990-05-22 US US07/526,143 patent/US5126148A/en not_active Expired - Fee Related
- 1990-05-22 KR KR1019900007373A patent/KR0157227B1/ko not_active IP Right Cessation
-
1995
- 1995-11-08 GR GR950403114T patent/GR3018004T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0401997A1 (en) | 1990-12-12 |
JPH02308799A (ja) | 1990-12-21 |
KR900018379A (ko) | 1990-12-21 |
EP0401997B1 (en) | 1995-09-06 |
GR3018004T3 (en) | 1996-02-29 |
ATE127527T1 (de) | 1995-09-15 |
DE69022121T2 (de) | 1996-04-04 |
CA2017279A1 (en) | 1990-11-22 |
RU2070046C1 (ru) | 1996-12-10 |
DK0401997T3 (da) | 1995-10-16 |
DE69022121D1 (de) | 1995-10-12 |
KR0157227B1 (ko) | 1998-10-15 |
US5126148A (en) | 1992-06-30 |
JP2926409B2 (ja) | 1999-07-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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