ES2077376T3 - Derivados de 2-aminopirimidina-4-carboxamida, su preparacion y su aplicacion terapeutica. - Google Patents

Derivados de 2-aminopirimidina-4-carboxamida, su preparacion y su aplicacion terapeutica.

Info

Publication number
ES2077376T3
ES2077376T3 ES92401771T ES92401771T ES2077376T3 ES 2077376 T3 ES2077376 T3 ES 2077376T3 ES 92401771 T ES92401771 T ES 92401771T ES 92401771 T ES92401771 T ES 92401771T ES 2077376 T3 ES2077376 T3 ES 2077376T3
Authority
ES
Spain
Prior art keywords
aminopyrimidine
carboxamide
derivatives
preparation
therapeutic application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92401771T
Other languages
English (en)
Inventor
Pascal George
Christian Maloizel
Benoit Marabout
Jean-Pierre Merly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9107938A external-priority patent/FR2678268B1/fr
Priority claimed from FR9206005A external-priority patent/FR2691148B1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of ES2077376T3 publication Critical patent/ES2077376T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)

Abstract

COMPUESTO, EN FORMA DE ENANTIOMERO PURO O DE MEZCLA DE ENANTIOMEROS, QUE RESPONDE A LA FORMULA GENERAL (I) EN LA QUE X REPRESENTA UNO O VARIOS SUSTITUYENTES ELEGIDOS ENTRE LOS ATOMOS DE HIDROGENO, DE FLUOR Y DE CLORO Y LOS GRUPO METILO, 1-METILETILO Y METOXI, N REPRESENTA EL NUMERO 2 O 3, M REPRESENTA EL NUMERO 1, EN CUYO CASO P REPRESENTA EL NUMERO 1, O BIEN M REPRESENTA EL NUMERO 0, EN CUYO CASO P REPRESENTA EL NUMERO 2, Q REPRESENTA EL NUMERO 0 O 1, Y R1 REPRESENTA UN ATOMO DE HIDROGENO. APLICACION EN TERAPIA.
ES92401771T 1991-06-27 1992-06-24 Derivados de 2-aminopirimidina-4-carboxamida, su preparacion y su aplicacion terapeutica. Expired - Lifetime ES2077376T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9107938A FR2678268B1 (fr) 1991-06-27 1991-06-27 Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
FR9206005A FR2691148B1 (fr) 1992-05-18 1992-05-18 Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
ES2077376T3 true ES2077376T3 (es) 1995-11-16

Family

ID=26228783

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92401771T Expired - Lifetime ES2077376T3 (es) 1991-06-27 1992-06-24 Derivados de 2-aminopirimidina-4-carboxamida, su preparacion y su aplicacion terapeutica.

Country Status (20)

Country Link
US (1) US5246939A (es)
EP (1) EP0520882B1 (es)
JP (1) JP3159525B2 (es)
KR (1) KR930000507A (es)
CN (1) CN1067887A (es)
AT (1) ATE124942T1 (es)
AU (1) AU645429B2 (es)
CA (1) CA2072434A1 (es)
CZ (1) CZ9202001A3 (es)
DE (1) DE69203401T2 (es)
DK (1) DK0520882T3 (es)
ES (1) ES2077376T3 (es)
FI (1) FI922981A (es)
GR (1) GR3017612T3 (es)
HU (1) HUT61745A (es)
IE (1) IE922092A1 (es)
IL (1) IL102329A0 (es)
MX (1) MX9203332A (es)
NO (1) NO922523L (es)
PL (1) PL295046A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9319534D0 (en) * 1993-09-22 1993-11-10 Boots Co Plc Therapeutic agents
AU3883099A (en) * 1998-05-06 1999-11-23 Duke University Method of treating bladder and lower urinary tract syndromes
RU2018145734A (ru) 2016-06-08 2020-07-14 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Химические соединения в качестве ингибиторов atf4 пути
KR102177766B1 (ko) * 2019-03-15 2020-11-11 주식회사 엠에스바이오 양막링 및 이의 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2618436B1 (fr) * 1987-07-23 1989-10-27 Synthelabo Derives de piperidine, leur preparation et leur application en therapeutique
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
FR2667317B1 (fr) * 1990-10-02 1992-12-04 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
EP0520882B1 (fr) 1995-07-12
HU9202142D0 (en) 1992-10-28
MX9203332A (es) 1992-12-01
US5246939A (en) 1993-09-21
AU1858792A (en) 1993-01-07
NO922523L (no) 1992-12-28
DE69203401D1 (de) 1995-08-17
AU645429B2 (en) 1994-01-13
DK0520882T3 (da) 1995-12-11
GR3017612T3 (en) 1996-01-31
NO922523D0 (no) 1992-06-26
ATE124942T1 (de) 1995-07-15
HUT61745A (en) 1993-03-01
DE69203401T2 (de) 1996-03-07
IL102329A0 (en) 1993-01-14
KR930000507A (ko) 1993-01-15
CN1067887A (zh) 1993-01-13
FI922981A0 (fi) 1992-06-26
FI922981A (fi) 1992-12-28
PL295046A1 (en) 1993-03-22
JPH05194419A (ja) 1993-08-03
CA2072434A1 (en) 1993-01-28
IE922092A1 (en) 1992-12-30
CZ9202001A3 (en) 1993-01-13
EP0520882A1 (fr) 1992-12-30
JP3159525B2 (ja) 2001-04-23

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