ES2072616T3 - Derivados de propilamina. - Google Patents

Derivados de propilamina.

Info

Publication number
ES2072616T3
ES2072616T3 ES91914457T ES91914457T ES2072616T3 ES 2072616 T3 ES2072616 T3 ES 2072616T3 ES 91914457 T ES91914457 T ES 91914457T ES 91914457 T ES91914457 T ES 91914457T ES 2072616 T3 ES2072616 T3 ES 2072616T3
Authority
ES
Spain
Prior art keywords
compound
general formula
propylamine derivatives
coupling
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91914457T
Other languages
English (en)
Inventor
William J Horgan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norgine Ltd
Original Assignee
Norgine Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norgine Ltd filed Critical Norgine Ltd
Application granted granted Critical
Publication of ES2072616T3 publication Critical patent/ES2072616T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
  • Circuits Of Receivers In General (AREA)

Abstract

NUEVOS DERIVADOS DE LA PROPILAMINA DE FORMULA GENERAL (I) Y SUS BASES CUATERNARIAS. TALES COMPUESTOS EXHIBEN ACTIVIDAD ANTIESPASMODICA. LOS COMPUESTOS (I) SE PUEDEN PREPARAR POR ACOPLAMIENTO DE UN COMPUESTO DE FORMULA (III) CON UN COMPUESTO DE FORMULA GENERAL (IV) PARA PRODUCIR UN COMPUESTO DE FORMULA GENERAL (V) Y REDUCIR EL COMPUESTO (V) A LA AMINA DE FORMULA GENERAL (I). EL AGENTE ACOPLANTE PUEDE SER UNA CARBODIMIDA DICICLOHEXIL Y EL AGENTE REDUCTOR PUEDE SER UN ANHIDRIDO DE LITIO Y ALUMINA.
ES91914457T 1990-08-08 1991-08-07 Derivados de propilamina. Expired - Lifetime ES2072616T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909017390A GB9017390D0 (en) 1990-08-08 1990-08-08 Improvements in or relating to propylamine derivatives

Publications (1)

Publication Number Publication Date
ES2072616T3 true ES2072616T3 (es) 1995-07-16

Family

ID=10680351

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91914457T Expired - Lifetime ES2072616T3 (es) 1990-08-08 1991-08-07 Derivados de propilamina.

Country Status (21)

Country Link
EP (1) EP0542837B1 (es)
JP (1) JP2766728B2 (es)
KR (1) KR0174525B1 (es)
AT (1) ATE122333T1 (es)
AU (1) AU641799B2 (es)
BR (1) BR9106733A (es)
CA (1) CA2088985A1 (es)
CZ (1) CZ281461B6 (es)
DE (1) DE69109682T2 (es)
DK (1) DK0542837T3 (es)
ES (1) ES2072616T3 (es)
GB (2) GB9017390D0 (es)
GR (1) GR1001327B (es)
HU (1) HUT66944A (es)
IE (1) IE71040B1 (es)
MX (1) MX9100593A (es)
PL (1) PL167155B1 (es)
PT (1) PT98599B (es)
SK (1) SK279235B6 (es)
WO (1) WO1992002488A1 (es)
ZA (1) ZA916242B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5984919A (en) * 1991-02-13 1999-11-16 Applied Medical Resources Corporation Surgical trocar
FR2869538B1 (fr) * 2004-04-30 2006-08-04 Cerep Sa Utilisation de l'alverine, seul ou en combinaison avec un antidepresseur tricyclique ou un antidepresseur inhibiteur specifique de la recapture de la serotonine pour le traitement de la depression
EP1641445A1 (fr) * 2003-06-13 2006-04-05 Cerep Utilisation de l'alverine, seul ou en combinaison avec un antidepresseur tricyclique ou un antidepresseur inhibiteur specifique de la recapture de la serotonine pour le traitement de la depression
FR2855970A1 (fr) * 2003-06-13 2004-12-17 Cerep Utilisation de l'alverine et de ses metabolites pour le traitement de la depression
FR2900337A1 (fr) * 2006-04-28 2007-11-02 Cerep Sa Utilisation de l'alverine pour le traitement des dysfonctions sexuelles
US8092778B2 (en) 2007-01-24 2012-01-10 Eden Energy Ltd. Method for producing a hydrogen enriched fuel and carbon nanotubes using microwave assisted methane decomposition on catalyst
CN108658786B (zh) * 2018-05-28 2019-12-03 吉林大学 一种降低阿尔维林中n-乙基-3-苯基丙胺残留的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD11922A (es) *
FR2356417A1 (fr) * 1976-07-01 1978-01-27 Roussel Uclaf Nouveaux derives de monohydroxyphenethylamines et leurs sels, procede de preparation et application a titre de medicaments de ces nouveaux produits
FR2436773A1 (fr) * 1978-09-22 1980-04-18 Roussel Uclaf Nouveaux derives du 3-(aminoethyl) phenol et leurs sels, procede de preparation et application a titre de medicaments

Also Published As

Publication number Publication date
EP0542837B1 (en) 1995-05-10
AU641799B2 (en) 1993-09-30
SK6693A3 (en) 1993-07-07
MX9100593A (es) 1992-04-01
GB2246778B (en) 1993-09-29
CA2088985A1 (en) 1992-02-09
DE69109682T2 (de) 1995-09-14
SK279235B6 (sk) 1998-08-05
IE71040B1 (en) 1997-01-15
KR0174525B1 (ko) 1999-04-01
JPH06500094A (ja) 1994-01-06
JP2766728B2 (ja) 1998-06-18
GB9017390D0 (en) 1990-09-19
HU9300299D0 (en) 1993-04-28
CZ281461B6 (cs) 1996-10-16
WO1992002488A1 (en) 1992-02-20
GB9117024D0 (en) 1991-09-18
DK0542837T3 (da) 1995-09-11
DE69109682D1 (en) 1995-06-14
GR1001327B (el) 1993-08-31
HUT66944A (en) 1995-01-30
IE912795A1 (en) 1992-02-12
AU8327291A (en) 1992-03-02
EP0542837A1 (en) 1993-05-26
ZA916242B (en) 1992-05-27
BR9106733A (pt) 1993-08-31
CZ9493A3 (en) 1993-05-12
ATE122333T1 (de) 1995-05-15
PT98599A (pt) 1992-06-30
PT98599B (pt) 1999-01-29
PL167155B1 (pl) 1995-08-31
GR910100343A (en) 1992-08-31
GB2246778A (en) 1992-02-12

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