JPS5716848A - Alkyl o-alpha-halogen-substituted acetoacetamidobenzoate and its preparation - Google Patents

Alkyl o-alpha-halogen-substituted acetoacetamidobenzoate and its preparation

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Publication number
JPS5716848A
JPS5716848A JP9083580A JP9083580A JPS5716848A JP S5716848 A JPS5716848 A JP S5716848A JP 9083580 A JP9083580 A JP 9083580A JP 9083580 A JP9083580 A JP 9083580A JP S5716848 A JPS5716848 A JP S5716848A
Authority
JP
Japan
Prior art keywords
alkyl
acetoacetamidobenzoate
alpha
halogen
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9083580A
Other languages
Japanese (ja)
Inventor
Tetsuzou Katou
Jiro Horiuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KANTO ISHI PHARMA CO Ltd
Original Assignee
KANTO ISHI PHARMA CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KANTO ISHI PHARMA CO Ltd filed Critical KANTO ISHI PHARMA CO Ltd
Priority to JP9083580A priority Critical patent/JPS5716848A/en
Publication of JPS5716848A publication Critical patent/JPS5716848A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A compound of formula I (X1 is H; X2 is Cl or Br; or both X1 and X2 are Br; R is alkyl).
EXAMPLE: Methyl o-α-dibromoacetoacetamidobenzoate.
USE: Synthetic intermediate of various chemicals. Extremely useful as a synthetic intermediate of pharmaceuticals having the activity of, e.g. antiphlogistic and analogesic agent.
PROCESS: The compound of formula I is prepared either by reacting 1mol of alkyl.o- acetoacetamidobenzoate with 2mol of bromine in alcohol (e.g. methanol, ethanol, etc.) at ≤20°C, or by reacting 1mol of alkyl.o-acetoacetamidobenzoate with 1mol of bromine or 2mol of hydrogen bromide in an alcohol in the presence of hydrogen peroxide.
COPYRIGHT: (C)1982,JPO&Japio
JP9083580A 1980-07-03 1980-07-03 Alkyl o-alpha-halogen-substituted acetoacetamidobenzoate and its preparation Pending JPS5716848A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9083580A JPS5716848A (en) 1980-07-03 1980-07-03 Alkyl o-alpha-halogen-substituted acetoacetamidobenzoate and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9083580A JPS5716848A (en) 1980-07-03 1980-07-03 Alkyl o-alpha-halogen-substituted acetoacetamidobenzoate and its preparation

Publications (1)

Publication Number Publication Date
JPS5716848A true JPS5716848A (en) 1982-01-28

Family

ID=14009638

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9083580A Pending JPS5716848A (en) 1980-07-03 1980-07-03 Alkyl o-alpha-halogen-substituted acetoacetamidobenzoate and its preparation

Country Status (1)

Country Link
JP (1) JPS5716848A (en)

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