ES2071706T3 - Metodo para fraccionar proteinas plasmaticas. - Google Patents

Metodo para fraccionar proteinas plasmaticas.

Info

Publication number
ES2071706T3
ES2071706T3 ES90113335T ES90113335T ES2071706T3 ES 2071706 T3 ES2071706 T3 ES 2071706T3 ES 90113335 T ES90113335 T ES 90113335T ES 90113335 T ES90113335 T ES 90113335T ES 2071706 T3 ES2071706 T3 ES 2071706T3
Authority
ES
Spain
Prior art keywords
treatment
plasma proteins
ethanol
concentration
phases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90113335T
Other languages
English (en)
Inventor
Yahiro C O The Green Cr Uemura
Kazuo C O The Green Cr Takechi
Kenji C O The Green Cro Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GREEN CROSS CORP
Mitsubishi Tanabe Pharma Corp
Original Assignee
GREEN CROSS CORP
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GREEN CROSS CORP, Green Cross Corp Japan filed Critical GREEN CROSS CORP
Application granted granted Critical
Publication of ES2071706T3 publication Critical patent/ES2071706T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes

Abstract

METODO DE FRACCIONAMIENTO DE PROTEINAS DE PLASMA QUE CONSISTE EN EL TRATAMIENTO DE UN MATERIAL QUE CONTENGA PROTEINAS DE PLASMA EN LA SIGUIENTE SECUENCIA DE FASES, SIEMPRE QUE LAS FASES QUE VAN DE LA (II) A LA (V) PUEDAN REALIZARSE EN UN ORDEN OPCIONAL: (I) TRATAMIENTO DE CONGELACION-DESHIELO (II) TRATAMIENTO CON UNA CONCENTRACION DE ETANOL DEL 5 AL 10% (III) TRATAMIENTO CON UN PERMUTADOR ANIONICO (IV) CROMATOGRAFIA DE AFINIDAD CON LISINA INMOVILIZADA (V) CROMATOGRAFIA DE AFINIDAD CON HEPARINA INMOVILIZADA (VI) TRATAMIENTO CON UNA CONCENTRACION DE ETANOL DEL 18 AL 30% (VII) TRATAMIENTO CON UNA CONCENTRACION DE ETANOL DEL 35 AL 45%.
ES90113335T 1989-07-12 1990-07-12 Metodo para fraccionar proteinas plasmaticas. Expired - Lifetime ES2071706T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18167289 1989-07-12

Publications (1)

Publication Number Publication Date
ES2071706T3 true ES2071706T3 (es) 1995-07-01

Family

ID=16104855

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90113335T Expired - Lifetime ES2071706T3 (es) 1989-07-12 1990-07-12 Metodo para fraccionar proteinas plasmaticas.

Country Status (8)

Country Link
US (1) US5138034A (es)
EP (1) EP0408029B1 (es)
JP (1) JP3018412B2 (es)
KR (1) KR910002894A (es)
CA (1) CA2019893A1 (es)
DE (1) DE69019074T2 (es)
DK (1) DK0408029T3 (es)
ES (1) ES2071706T3 (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993005067A1 (en) * 1991-09-05 1993-03-18 Baxter International, Inc. Topical fibrinogen complex
US5792835A (en) * 1991-09-05 1998-08-11 Baxter International Inc. Method of preparing a topical fibrinogen complex
US5319072A (en) * 1992-01-10 1994-06-07 Alpha Therapeutic Corporation Human antithrombin-III preparation
IT1262899B (it) * 1992-03-27 1996-07-22 Sclavo Spa Processo per l'isolamento di fattore ix, fattore x e fattore ii altamente purificati dal complesso protrombinico o dal plasma umano
DK0659767T4 (da) * 1993-12-27 2003-02-10 Zlb Bioplasma Ag Fremgangsmåde til fremstilling af et koncentrat af anti-D-immunoglobulin G og et farmaceutisk præparat, som indeholder dette
JPH07308190A (ja) * 1994-05-18 1995-11-28 Green Cross Corp:The トロンビンの製造方法
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
JP3944267B2 (ja) * 1996-08-09 2007-07-11 財団法人化学及血清療法研究所 プロトロンビンの活性化方法および該方法に基づくトロンビンの製造方法
AUPO776897A0 (en) * 1997-07-09 1997-07-31 Csl Limited A method of achieving production gains in livestock and agents useful for same
US5945457A (en) * 1997-10-01 1999-08-31 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science Process for preparing biologically compatible polymers and their use in medical devices
CN1284881A (zh) * 1997-11-05 2001-02-21 吉富制药株式会社 肝素辅助因子ⅱ制剂及其制备方法
DE69826531T2 (de) * 1998-06-23 2005-09-22 Shanbrom Technologies, LLC, Ojai Verfahren und vorrichtung zur herstellung von gereinigten plasmaproteinen
US6194394B1 (en) * 1998-07-01 2001-02-27 Sigma-Aldrich Co. Coagulation controls for prothrombin time (PT) and activated partial thromboplastin time (APTT) assays
CA2277372C (en) * 1998-07-13 2011-03-15 Tran Quang Minh Affinity immobilised metal resins
US6274090B1 (en) * 1998-08-05 2001-08-14 Thermogenesis Corp. Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
PT2130554E (pt) 1999-02-22 2012-11-19 Univ Connecticut Formulações de factor viii isentas de albumina
US6472162B1 (en) * 1999-06-04 2002-10-29 Thermogenesis Corp. Method for preparing thrombin for use in a biological glue
US6458322B1 (en) 2000-09-08 2002-10-01 Bioavailability Systems, Llc Method for simplified shipping of clinical specimens and optional direct analysis
US6957672B2 (en) * 2001-07-25 2005-10-25 Imperial Chemical Industries Plc Method for ensuring that coating compositions have correct color
JP4703922B2 (ja) * 2001-09-27 2011-06-15 日本製薬株式会社 蛋白質の精製法
DE102004009400A1 (de) 2004-02-24 2005-09-08 Zlb Behring Gmbh Fibrinogen Reinigung
JP4970260B2 (ja) 2004-08-20 2012-07-04 プロメティック バイオサイエンシズ，リミテッド 親和性クロマトグラフィーによるタンパク質の逐次的単離および精製スキーム
JP2006160731A (ja) * 2004-11-11 2006-06-22 Kuraray Medical Inc 血液成分回収装置
US20070048387A1 (en) 2005-09-01 2007-03-01 Edwards Jeffrey D Tissue disruption treatment and composition for use thereof
US20070054031A1 (en) * 2005-09-02 2007-03-08 Keshun Liu Methods of extracting, concentrating and fractionating proteins and other chemical components
WO2007124541A1 (en) 2006-04-28 2007-11-08 Cambridge Scientific Pty Ltd Cox-2 inhibitor
FR2922024B1 (fr) * 2007-10-04 2011-03-25 Stago Diagnostica Methode d'ajustement de la calibration de tests diagnostiques
US20100168018A1 (en) * 2008-11-07 2010-07-01 Baxter International Inc. Factor viii formulations
JPWO2012036140A1 (ja) * 2010-09-14 2014-02-03 株式会社カネカ クリングル配列を有する蛋白質またはペプチドを精製または除去するアフィニティ担体、及びそれを用いた精製方法、除去方法
US9534029B2 (en) 2012-10-03 2017-01-03 Csl Behring Ag Method of purifying proteins
KR102125695B1 (ko) * 2012-10-03 2020-06-24 체에스엘 베링 아게 단백질 정제 방법
US9663553B2 (en) 2014-01-29 2017-05-30 Hemarus Therapeutics Limited Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma
US9932388B2 (en) 2014-11-13 2018-04-03 Hemarus Therapeutics Limited Chromatographic process for producing high purity fibrinogen and thrombin
CN108026507A (zh) * 2015-04-02 2018-05-11 K·黄 由组分vi制造afod静脉注射剂的方法
GB201506117D0 (en) 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
GB201506113D0 (en) 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
KR101841587B1 (ko) 2016-01-12 2018-05-14 주식회사 녹십자홀딩스 피브리노겐의 정제방법
UA126232C2 (uk) * 2016-08-18 2022-09-07 Алкахест, Інк. Спосіб лікування когнітивного розладу, пов'язаного зі старінням, та набір, що містить фракцію плазми крові
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2710293A (en) * 1953-10-30 1955-06-07 Olin Mathieson Blood fractionation
US4025618A (en) * 1974-09-03 1977-05-24 Baxter Travenol Laboratories, Inc. Method for separation of cryoprecipitate from blook plasma

Also Published As

Publication number Publication date
JP3018412B2 (ja) 2000-03-13
KR910002894A (ko) 1991-02-26
DK0408029T3 (da) 1995-07-17
DE69019074D1 (de) 1995-06-08
CA2019893A1 (en) 1991-01-12
EP0408029A1 (en) 1991-01-16
JPH03128398A (ja) 1991-05-31
DE69019074T2 (de) 1995-09-28
US5138034A (en) 1992-08-11
EP0408029B1 (en) 1995-05-03

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