ES2070828T3 - Estimulacion de la produccion de proteina en bacterias empleando un nuevo sitio de union al ribosoma. - Google Patents

Estimulacion de la produccion de proteina en bacterias empleando un nuevo sitio de union al ribosoma.

Info

Publication number
ES2070828T3
ES2070828T3 ES87870039T ES87870039T ES2070828T3 ES 2070828 T3 ES2070828 T3 ES 2070828T3 ES 87870039 T ES87870039 T ES 87870039T ES 87870039 T ES87870039 T ES 87870039T ES 2070828 T3 ES2070828 T3 ES 2070828T3
Authority
ES
Spain
Prior art keywords
bacteria
protein production
ribosoma
stimulation
new linkage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87870039T
Other languages
English (en)
Inventor
Peter Olafs Olins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Application granted granted Critical
Publication of ES2070828T3 publication Critical patent/ES2070828T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA NUEVOS SITIOS DE UNION A RIBOSOMAS QUE SON UTILES PARA AUMENTAR LA PRODUCCION DE PROTEINAS EN BACTERIAS. TMBIEN SE PROPORCIONAN METODOS, GENES, BACTERIAS Y COMPUESTOS INTERMEDIOS UTILES QUE EMPLEAN LOS NUEVOS SITIOS DE UNION A RIBOSOMAS. TAMBIEN SE PROPORCIONA UN NUEVO SITIO DE INTERACCION DIFERENTE DE UNA SECUENCIA SHINE-DALGARNO ENTRE EL ARN RIBOSOMICO 16S Y EL ARN MENSAJERO.
ES87870039T 1986-03-27 1987-03-26 Estimulacion de la produccion de proteina en bacterias empleando un nuevo sitio de union al ribosoma. Expired - Lifetime ES2070828T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84515986A 1986-03-27 1986-03-27
US582187A 1987-02-04 1987-02-04

Publications (1)

Publication Number Publication Date
ES2070828T3 true ES2070828T3 (es) 1995-06-16

Family

ID=26674811

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87870039T Expired - Lifetime ES2070828T3 (es) 1986-03-27 1987-03-26 Estimulacion de la produccion de proteina en bacterias empleando un nuevo sitio de union al ribosoma.

Country Status (12)

Country Link
EP (1) EP0241446B1 (es)
JP (1) JP2511948B2 (es)
AT (1) ATE119200T1 (es)
AU (1) AU597951B2 (es)
CA (1) CA1340091C (es)
DE (1) DE3751100T2 (es)
DK (1) DK154487A (es)
ES (1) ES2070828T3 (es)
HU (1) HUT43625A (es)
IE (1) IE67890B1 (es)
IL (1) IL82017A (es)
NZ (1) NZ219789A (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0372005A4 (en) * 1987-10-30 1990-06-26 Oncogen EXPRESSION SYSTEMS FOR THE PREPARATION OF POLYPEPTIDES IN PROKARYOTIC CELLS.
EP0404824A1 (en) * 1988-03-11 1991-01-02 The Upjohn Company Ribosome binding site
US5268284A (en) * 1988-03-11 1993-12-07 The Upjohn Company Ribosome binding site
JPH0213382A (ja) * 1988-03-30 1990-01-17 Monsanto Co グラムネガテイブ微生物での構造遺伝子の調節発現法
JP2862137B2 (ja) * 1988-08-11 1999-02-24 古河電気工業株式会社 超電導トランジスタ
US5279947A (en) * 1988-08-24 1994-01-18 Sanofi DNA sequence participating in the regulation of the expression of a DNA sequence coding for a precursor of a polypeptide, expression vectors and process for the periplasmic production of the polypeptide
FR2636644B1 (fr) * 1988-08-24 1990-12-28 Sanofi Sa Sequence d'adn participant a la regulation de l'expression d'une sequence d'adn codant pour un precurseur d'un polypeptide, vecteurs d'expression et procede de production periplasmique du polypeptide
US5089473A (en) 1988-08-29 1992-02-18 Monsanto Company Somatotropin variants and their use
GR1002113B (en) * 1988-09-02 1996-02-02 Oncogen Expression systems for preparation of polypeptides in prokaryotic cells
US6271444B1 (en) 1998-07-10 2001-08-07 Calgene Llc Enhancer elements for increased translation in plant plastids
EP1022339B1 (en) 1999-01-20 2006-02-01 Bayer HealthCare AG Plasmids, their construction and their use in the manufacture of interleukin-4 and interleukin-4 muteins
EP1022337B1 (en) * 1999-01-20 2006-07-26 Bayer HealthCare AG Plasmids, their construction and their use in the manufacture of interleukin-4 and interleukin-4 muteins
JP2005230001A (ja) * 2004-01-20 2005-09-02 Mariusu:Kk リボソームｒｎａ塩基配列に相補的な１本鎖ｄｎａオリゴマーを用いたたんぱく質翻訳調節因子及びリボソームｒｎａ塩基配列に相補的な１本鎖ｄｎａオリゴマーを用いたイニシエーションファクター並びにリボソームｒｎａ塩基配列に相補的な１本鎖ｄｎａオリゴマーを用いたたんぱく質翻訳調節方法
US20090093023A1 (en) * 2007-01-19 2009-04-09 Gregg Bogosian Elements for improved expression of bovine somatotropin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201918A (en) 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
GR81701B (es) * 1983-01-18 1984-12-12 Lilly Co Eli
EP0178863A1 (en) * 1984-10-15 1986-04-23 Schering Corporation Novel expression systems utilizing bacteriophage T7 promoters and gene sequences
US5037806A (en) 1985-02-22 1991-08-06 Monsanto Company Biologically active method using somatotropins

Also Published As

Publication number Publication date
JPS63289A (ja) 1988-01-05
AU597951B2 (en) 1990-06-14
IE67890B1 (en) 1996-05-01
IE870782L (en) 1987-09-27
IL82017A (en) 1996-01-19
EP0241446A2 (en) 1987-10-14
DK154487A (da) 1987-12-21
DK154487D0 (da) 1987-03-26
DE3751100T2 (de) 1995-09-07
CA1340091C (en) 1998-10-20
JP2511948B2 (ja) 1996-07-03
IL82017A0 (en) 1987-10-20
NZ219789A (en) 1990-09-26
DE3751100D1 (de) 1995-04-06
EP0241446A3 (en) 1988-11-09
ATE119200T1 (de) 1995-03-15
EP0241446B1 (en) 1995-03-01
AU7066187A (en) 1987-10-01
HUT43625A (en) 1987-11-30

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