ES2068392T3 - Procedimiento de purificacion de interferon. - Google Patents

Procedimiento de purificacion de interferon.

Info

Publication number
ES2068392T3
ES2068392T3 ES90909823T ES90909823T ES2068392T3 ES 2068392 T3 ES2068392 T3 ES 2068392T3 ES 90909823 T ES90909823 T ES 90909823T ES 90909823 T ES90909823 T ES 90909823T ES 2068392 T3 ES2068392 T3 ES 2068392T3
Authority
ES
Spain
Prior art keywords
interferon
purification procedure
solution
crude
column
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90909823T
Other languages
English (en)
Inventor
Hakan Borg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bionative AB
Original Assignee
Bionative AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bionative AB filed Critical Bionative AB
Application granted granted Critical
Publication of ES2068392T3 publication Critical patent/ES2068392T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

UN PROCESO PARA LA PURIFICACION DE UN INTERFERON LEUCOCITO HUMANO QUE COMPRENDE LAS FASES DE A) APLICAR UNA SOLUCION DE DICHO INTERFERON CRUDO EN UNA COLUMNA DE ADSORCION DE INMUNO-AFINIDAD; B) ELUDIR EL INTERFERON ABSORBIDO DE DICHA COLUMNA UTILIZANDO UNA SOLUCION BUFER; C) CONCENTRANDO EL ELUYENTE RESULTANTE DE LA FASE B) CON UNA SOLUCION DE TIOCIANATO MEDIANTE PRECIPITACION O CROMATOGRAFIA DE INTERCAMBIO; Y D) RECUPERACION DEL INTERFERON PRECIPITADO OBTENIDO EN LA FASE C).
ES90909823T 1989-06-20 1990-06-06 Procedimiento de purificacion de interferon. Expired - Lifetime ES2068392T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8902230A SE468251B (sv) 1989-06-20 1989-06-20 Reningsprocess foer interferon

Publications (1)

Publication Number Publication Date
ES2068392T3 true ES2068392T3 (es) 1995-04-16

Family

ID=20376336

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90909823T Expired - Lifetime ES2068392T3 (es) 1989-06-20 1990-06-06 Procedimiento de purificacion de interferon.

Country Status (12)

Country Link
EP (1) EP0478659B1 (es)
JP (1) JP3158254B2 (es)
AT (1) ATE118782T1 (es)
CA (1) CA2062729C (es)
DE (1) DE69017211T2 (es)
DK (1) DK0478659T3 (es)
ES (1) ES2068392T3 (es)
FI (1) FI98218C (es)
HK (1) HK1007747A1 (es)
NO (1) NO300895B1 (es)
SE (1) SE468251B (es)
WO (1) WO1990015817A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1315699A (en) * 1997-11-12 1999-05-31 Life Technologies, Inc. Device and methods for purifying biological molecules using low volumes of chromatographic and adsorptive media
FI105319B (fi) * 1998-06-10 2000-07-31 Suomen Punainen Risti Veripalv Menetelmä multikomponentti-alfa-interferonin valmistamiseksi

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI77877C (fi) * 1979-04-20 1989-05-10 Technobiotic Ltd Foerfarande foer framstaellning och rening av human le-formig interferonprotein.
DE3211263A1 (de) 1981-03-31 1983-01-27 Otsuka Pharmaceutical Co. Ltd., Tokyo Human-interferon verwandte peptide, antigene und antikoerper, sowie verfahren zu deren herstellung
DE3306060A1 (de) 1983-02-22 1984-08-23 Boehringer Ingelheim International GmbH, 6507 Ingelheim Neue immunglobulin-produzierende hybridzellinien, deren verwendung und verfahren zu deren herstellung
SE8502430L (sv) 1985-05-15 1986-11-16 Kabivitrum Ab En cdna-molekyl som kodar for expressionen av en polypeptid av typen interferon alfa, en bakteriell eller celluler verd transformerad med en sadan molekyl och en polypeptid som uppvisar interferonaktivetet framstelld me

Also Published As

Publication number Publication date
WO1990015817A1 (en) 1990-12-27
SE468251B (sv) 1992-11-30
FI916021A0 (fi) 1991-12-19
HK1007747A1 (en) 1999-04-23
DE69017211D1 (de) 1995-03-30
JPH04506075A (ja) 1992-10-22
FI98218B (fi) 1997-01-31
NO915032D0 (no) 1991-12-19
ATE118782T1 (de) 1995-03-15
EP0478659A1 (en) 1992-04-08
CA2062729A1 (en) 1990-12-21
NO300895B1 (no) 1997-08-11
CA2062729C (en) 2001-12-04
DE69017211T2 (de) 1995-06-22
JP3158254B2 (ja) 2001-04-23
SE8902230L (sv) 1990-12-21
SE8902230D0 (sv) 1989-06-20
NO915032L (no) 1992-02-07
FI98218C (fi) 1997-05-12
DK0478659T3 (da) 1995-05-08
EP0478659B1 (en) 1995-02-22

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