ES2065957T3 - Metodo para preparar esteres de acido 3-fenilglicidico opticamente activos. - Google Patents

Metodo para preparar esteres de acido 3-fenilglicidico opticamente activos.

Info

Publication number
ES2065957T3
ES2065957T3 ES89116104T ES89116104T ES2065957T3 ES 2065957 T3 ES2065957 T3 ES 2065957T3 ES 89116104 T ES89116104 T ES 89116104T ES 89116104 T ES89116104 T ES 89116104T ES 2065957 T3 ES2065957 T3 ES 2065957T3
Authority
ES
Spain
Prior art keywords
optically active
acid esters
preparing optically
phenylglicidic
phenylglicidic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89116104T
Other languages
English (en)
Inventor
Takeji Shibatani
Katsuhiko Nakamichi
Hiroaki Matsumae
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Application granted granted Critical
Publication of ES2065957T3 publication Critical patent/ES2065957T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction

Abstract

SE PRESENTA UN METODO PARA PREPARAR UN COMPUESTO DE ACIDO 3 - FENIL GLICIDICO OPTICAMENTE ACTIVO QUE COMPRENDE PERMITIR QUE UNA ENZIMA QUE TENGA LA HABILIDAD DE HIDROLIZAR ESTEREOSELECTIVAMENTE UN ENLACE DE UN ESTER QUE ACTUE SOBRE UN ACIDO 3 - FENIL GLICIDICO QUE PUEDE ESTAR SUSTITUIDO O INSUSTITUIDO EN EL GRUPO FENIL Y DE ESTA FORMA HIDROLIZAR ESTEREOSELECTIVAMENTE UNO DE LOS ISOMEROS OPTICAMENTE ACTIVOS Y SEPARAR Y RECOGER EL ANTIPODO DE LA MEZCLA DE REACCION.
ES89116104T 1988-09-02 1989-08-31 Metodo para preparar esteres de acido 3-fenilglicidico opticamente activos. Expired - Lifetime ES2065957T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22101688 1988-09-02

Publications (1)

Publication Number Publication Date
ES2065957T3 true ES2065957T3 (es) 1995-03-01

Family

ID=16760161

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89116104T Expired - Lifetime ES2065957T3 (es) 1988-09-02 1989-08-31 Metodo para preparar esteres de acido 3-fenilglicidico opticamente activos.

Country Status (12)

Country Link
EP (1) EP0362556B1 (es)
KR (1) KR960004455B1 (es)
CN (1) CN1041785A (es)
AT (1) ATE113661T1 (es)
AU (1) AU619890B2 (es)
DE (1) DE68919184T2 (es)
DK (1) DK173105B1 (es)
ES (1) ES2065957T3 (es)
FI (1) FI95931C (es)
HU (1) HU203581B (es)
IE (1) IE65881B1 (es)
IL (1) IL91453A0 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6521445B1 (en) * 1988-10-26 2003-02-18 Sepracor, Inc. Process for preparing optically active glycidate esters
US5274300A (en) 1988-10-26 1993-12-28 Sepracor, Inc. Enzymatic hydrolysis of glycidate esters in the presence of bisulfite anion
DE3927370A1 (de) * 1989-08-19 1991-02-21 Bayer Ag Verfahren zur herstellung von clausenamid und neoclausenamid und deren derivate
US5244803A (en) * 1989-09-13 1993-09-14 Tanabe Seiyaku Co., Ltd. Process for preparing optically active 3-phenylglycidic acid esters
ATE139563T1 (de) * 1990-03-13 1996-07-15 Tanabe Seiyaku Co Esterase von serratia und verfahren zur herstellung
JPH0779706B2 (ja) * 1990-03-22 1995-08-30 田辺製薬株式会社 ２―クロロ―３―ヒドロキシ―３―フエニルプロピオン酸エステル類の製法
IT1249777B (it) * 1990-05-17 1995-03-18 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem
FR2672600B1 (fr) * 1991-02-08 1994-10-14 Synthelabo Procede de preparation du (-)-(2r,3s)-2,3-epoxy-3-(4-methoxyphenyl) propionate de methyle.
FI93833C (fi) * 1992-05-14 1995-06-12 Orion Yhtymae Oy Menetelmä propionihappojohdosten valmistamiseksi
MX9302853A (es) * 1992-05-15 1993-11-01 Syntex Pharma Int Proceso enzimatico para producir acido (s)-6-metoxi-alfa-metil-2-naftalenacetico.
US6020174A (en) * 1992-07-27 2000-02-01 The Board Of Governors For Higher Education Chemoenzymatic synthesis of the taxol C-13 side chain N-benzolyl- (2R,3S)-Phenylisoserine
NL9202208A (nl) * 1992-12-18 1994-07-18 Dsm Nv Werkwijze voor de enzymatische bereiding van optisch aktieve glycidezure esters.
DK0786012T3 (da) * 1994-10-12 1999-08-23 Du Pont Enzymatisk fremgangsmåde til fremstilling af kiral-alfa-tertiære carboxylsyreestere
US5658796A (en) * 1995-06-07 1997-08-19 Seprachem, Inc. Optical resolution of alkyl chroman-2-carboxylates
US5529929A (en) * 1995-06-07 1996-06-25 Seprachem, Inc. Optical resolution of alkyl 1,4-benzodioxan-2-carboxylates using esterase from serratia marcescens
IL121525A0 (en) * 1996-08-26 1998-02-08 Tanabe Seiyaku Co Process for preparing optically active benzothiazepine compound and intermediate therefor
IL123352A0 (en) * 1997-02-27 1998-09-24 Tanabe Seiyaku Co Process for preparing an optically active trans-3-substituted glycidic acid ester
KR20010013668A (ko) * 1997-06-11 2001-02-26 찌바따 이찌로 광학 활성 페닐옥시란 화합물의 제조방법
US7169944B2 (en) 2002-09-25 2007-01-30 Tosoh Corporation Optically active epoxy compounds and processes for their production
KR100846676B1 (ko) * 2006-04-27 2008-07-16 엔자이텍 주식회사 효소적 방법에 의한 광학활성 2-할로-2-(엔-치환된페닐)아세트산 에스테르와 2-할로-2-(엔-치환된페닐)아세트산의 제조 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4585768A (en) * 1984-04-10 1986-04-29 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivatives and processes for preparing the same
DE3532026A1 (de) * 1985-09-09 1987-03-19 Hoechst Ag Verfahren zur herstellung optisch aktiver (alpha)-phenoxypropionsaeure und deren derivate
IT1189069B (it) * 1986-03-14 1988-01-28 Donegani Guido Ist Processo per la preparazione biotecnologica della l(-)-carnitina cloruro
EP0488999B1 (en) * 1986-04-16 1997-07-09 Sumitomo Chemical Company Limited A method for producing optically active cyclopropane carboxylic acid

Also Published As

Publication number Publication date
ATE113661T1 (de) 1994-11-15
FI894022A0 (fi) 1989-08-28
EP0362556A1 (en) 1990-04-11
HUT52162A (en) 1990-06-28
IL91453A0 (en) 1990-04-29
IE65881B1 (en) 1995-11-29
DE68919184D1 (de) 1994-12-08
KR960004455B1 (ko) 1996-04-06
IE892817L (en) 1990-03-02
EP0362556B1 (en) 1994-11-02
DE68919184T2 (de) 1995-04-13
HU203581B (en) 1991-08-28
AU4097789A (en) 1990-03-08
FI894022A (fi) 1990-03-03
DK434889A (da) 1990-03-03
FI95931B (fi) 1995-12-29
CN1041785A (zh) 1990-05-02
FI95931C (fi) 1996-04-10
AU619890B2 (en) 1992-02-06
DK173105B1 (da) 2000-01-17
DK434889D0 (da) 1989-09-01
KR900004711A (ko) 1990-04-12

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