ES2065034T3 - Sistema compuesto molecular para la terapia contraescalativa de las enfermedades infecciosas viricas. - Google Patents
Sistema compuesto molecular para la terapia contraescalativa de las enfermedades infecciosas viricas.Info
- Publication number
- ES2065034T3 ES2065034T3 ES91909678T ES91909678T ES2065034T3 ES 2065034 T3 ES2065034 T3 ES 2065034T3 ES 91909678 T ES91909678 T ES 91909678T ES 91909678 T ES91909678 T ES 91909678T ES 2065034 T3 ES2065034 T3 ES 2065034T3
- Authority
- ES
- Spain
- Prior art keywords
- lpl
- plp
- units
- infectious diseases
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000035473 Communicable disease Diseases 0.000 title abstract 3
- 230000003612 virological effect Effects 0.000 title abstract 3
- 239000002131 composite material Substances 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 3
- 150000004676 glycans Chemical class 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 3
- 229920001282 polysaccharide Polymers 0.000 abstract 3
- 239000005017 polysaccharide Substances 0.000 abstract 3
- NGVDGCNFYWLIFO-UHFFFAOYSA-N pyridoxal 5'-phosphate Chemical compound CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O NGVDGCNFYWLIFO-UHFFFAOYSA-N 0.000 abstract 3
- 239000002023 wood Substances 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 2
- 238000000926 separation method Methods 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 208000030507 AIDS Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000003763 carbonization Methods 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
- 238000000108 ultra-filtration Methods 0.000 abstract 1
- 235000013311 vegetables Nutrition 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
LA INVENCION CONCIERNE A UN SISTEMA COMPUESTO MOLECULAR PARA LA QUIMIOTERAPIA RESTITUTIVA DE ENFERMEDADES INFECCIOSAS VIRALES, OBTENIBLE MEDIANTE (I) LA PRODUCCION DE UNIDADES DE LIGNINA RICAS EN POLISACARIDOS (PLP) MEDIANTE: EXTRACCION EN MEDIOS ACUOSOS EN UN MEDIO DEBILMENTE ACIDO HASTA ALCALINO DE MADERA O MATERIALES TIPO MADERA TAMBIEN DE (O) CULTIVOS CELULARES VEGETALES (A); SEPARACION DE LOS COMPONENTES SOLIDOS INSOLUBLES; (II) PRODUCCION DE UNIDADES LIGNOIDES POBRES EN POLISACARIDOS DE BAJO PESO MOLECULAR (LPL) MEDIANTE: EXTRACCION ACUOSO-ALCALINA (PH 7-14) DE PRODUCTOS DE CARBONIZACION DE LA MADERA O MATERIALES TIPO MADERA BIOCONVERTIDOS (B); SEPARACION DE LOS COMPONENTES SOLIDOS INSOLUBLES EN ALCALIS ; (III) PRODUCCION DE UN POLIMERIZADO MIXTO SOLUBLE EN AGUA LD (PLP=LPL) MEDIANTE: TRANSFORMACION DEL PRODUCTO DE LA ETAPA I), LAS UNIDADES DE LIGNINA RICAS EN POLISACARIDOS (PLP) CON LOS PRODUCTOS DE LA ETAPA II), LAS UNIDADES LIGNOIDES POBRES EN POLISACARIDOS (LPL) BAJO CONDICIONES ACUOSO-ALCALINAS (PH 9-12); AISLAMIENTO DE LAS FRACCIONES LD DE ESTE POLIMERIZADO MIXTO HD-PLP=LPL MEDIANTE ULTRAFILTRACION A UNOS VALORES DE CORTE NOMINALES DE APROX. 15 A 40 KD, EN DONDE SE DESECHA EL RETENTADO; TRATAMIENTO DE LA SOLUCION CON UN INTERCAMBIADOR DE CATIONES H+ A UN PH DE 3 HASTA 7,0, ASI COMO TRATAMIENTO POSTERIOR DEL SISTEMA ACIDO LD(LPL-PLP), QUE SE PUEDE APLICAR ESPECIALMENTE COMO SISTEMA DE SUSTANCIAS ACTIVAS INHIBIDORAS DE VIRUS APLICABLE PARENTERAL O LOCALMENTE PARA COMBATIR LAS ENFERMEDADES INFECCIOSAS VIRALES, EN DONDE LOS VIRUS PUEDEN SER RETROVIRUS, ESPECIALMENTE DEL TIPO HIV, TAMBIEN VIRUS DEL SIDA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4017091A DE4017091A1 (de) | 1990-05-27 | 1990-05-27 | Molekuelverbundsystem zur kontra-eskalativen therapie viraler infektionskrankheiten |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2065034T3 true ES2065034T3 (es) | 1995-02-01 |
Family
ID=6407309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91909678T Expired - Lifetime ES2065034T3 (es) | 1990-05-27 | 1991-05-27 | Sistema compuesto molecular para la terapia contraescalativa de las enfermedades infecciosas viricas. |
Country Status (17)
Country | Link |
---|---|
US (2) | US5554596A (es) |
EP (1) | EP0535001B1 (es) |
JP (1) | JP2905289B2 (es) |
AT (1) | ATE110275T1 (es) |
AU (1) | AU663684B2 (es) |
BG (1) | BG61154B1 (es) |
CA (1) | CA2084093C (es) |
DE (2) | DE4017091A1 (es) |
DK (1) | DK0535001T3 (es) |
ES (1) | ES2065034T3 (es) |
FI (1) | FI925363A (es) |
HU (2) | HUT68910A (es) |
NO (1) | NO306049B1 (es) |
PL (1) | PL168266B1 (es) |
RO (1) | RO113430B1 (es) |
RU (1) | RU2104016C1 (es) |
WO (1) | WO1991018616A1 (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6348503B1 (en) | 1996-02-12 | 2002-02-19 | Meryl J. Squires | Method and topical treatment composition for herpesvirus hominis |
US6355684B1 (en) | 1990-10-11 | 2002-03-12 | Meryl J. Squires | Antimicrobial treatment for herpes simplex virus and other infectious diseases |
US6350784B1 (en) | 1996-02-12 | 2002-02-26 | Meryl J. Squires | Antimicrobial prevention and treatment of human immunedeficiency virus and other infectious diseases |
DE4236346A1 (de) * | 1992-10-28 | 1994-05-05 | Chantal Dr Mach | Wirkstoffgruppe, Verfahren zu ihrer Herstellung sowie ihre Verwendung |
DE4316347C1 (de) * | 1993-02-26 | 1994-08-18 | Ina Dr Levi | Verfahren zur Herstellung einer pharmazeutischen Zubereitung und Verwendung derselben zur Behandlung bestimmter Erkrankungen |
DE4415087A1 (de) * | 1994-04-29 | 1995-11-09 | Zschiegner Hans Joachim Dr | Mittel als Wirkstoffe bzw. Wirkstoffgemische zur Anwendung in der Balneotherapie, Gesundheitspflege und Kosmetik und Verfahren zur Herstellung pharmazeutischer Erzeugnisse sowie Verfahren zu ihrer Anwendung |
DE4417254A1 (de) * | 1994-05-17 | 1995-11-23 | Zschiegner Hans Joachim Dr | Mittel als Wirkstoffe bzw. Wirkstoffgemische für Tierarzneimittel, Tiergesundheitspflegemittel, Medizinalfuttermittel, Ergotropika und zur Anwendung in der Veterinärhygiene sowie Verfahren zur Herstellung der Mittel und pharmazeutischer Erzeugnisse und Methoden ihrer Anwendung |
FR2731162B1 (fr) * | 1995-03-01 | 1997-04-11 | Oreal | Procede d'extraction d'au moins un actif a partir de cellules vegetales indifferenciees |
US20090191288A1 (en) * | 1996-02-12 | 2009-07-30 | Squires Meryl J | Composition to Treat Herpes, Pseudomonas, Staph, Hepatitis and Other Infectious Diseases |
FR2757046B1 (fr) * | 1996-12-16 | 1999-03-05 | Dior Christian Parfums | Utilisation d'un extrait de resine d'okoume, dans les domaines cosmetique et pharmaceutique, notamment dermatologiques |
US6258577B1 (en) | 1998-07-21 | 2001-07-10 | Gambro, Inc. | Method and apparatus for inactivation of biological contaminants using endogenous alloxazine or isoalloxazine photosensitizers |
RU2141335C1 (ru) * | 1998-12-30 | 1999-11-20 | Общество с ограниченной ответственностью "Лигфарм" | Противоопухолевое средство "олипифат" и способ его получения |
US6268120B1 (en) | 1999-10-19 | 2001-07-31 | Gambro, Inc. | Isoalloxazine derivatives to neutralize biological contaminants |
US7648699B2 (en) | 2000-06-02 | 2010-01-19 | Caridianbct Biotechnologies, Llc | Preventing transfusion related complications in a recipient of a blood transfusion |
TW590780B (en) | 2000-06-02 | 2004-06-11 | Gambro Inc | Additive solutions containing riboflavin |
US7985588B2 (en) | 2000-06-02 | 2011-07-26 | Caridianbct Biotechnologies, Llc | Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light |
US9044523B2 (en) | 2000-06-15 | 2015-06-02 | Terumo Bct, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
RU2172176C1 (ru) * | 2000-06-19 | 2001-08-20 | Общество с ограниченной ответственностью "Нобель" | Способ получения противовирусного средства |
US6866875B2 (en) * | 2001-09-26 | 2005-03-15 | Tampa Bay Research Institute | Pine cone extracts and uses thereof |
US7838046B2 (en) * | 2001-09-26 | 2010-11-23 | Tampa Bay Research Institute | Plant extracts and uses thereof |
US6703053B2 (en) * | 2001-10-24 | 2004-03-09 | Tampa Bay Research Institute | Anti-HSV agent for inhibiting replication of HSV-1 and HSV-2 and method of producing a substance having anti-HSV activity |
EP2422805A1 (en) * | 2003-12-24 | 2012-02-29 | Ramot at Tel-Aviv University Ltd. | Antiviral preparations obtained from a natural cinnamon extract |
RU2401117C1 (ru) * | 2009-04-06 | 2010-10-10 | Открытое Акционерное Общество Завод Экологической Техники И Экопитания "Диод" | Средство для профилактики гриппа и острых респираторных заболеваний |
JP2010273569A (ja) * | 2009-05-26 | 2010-12-09 | Wasaburo Sato | メタボリックシンドローム改善作用を有する飲料及びサプリメント |
US20100303935A1 (en) * | 2009-05-29 | 2010-12-02 | Squires Meryl J | Medicinal Composition |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4185097A (en) * | 1978-01-09 | 1980-01-22 | A. H. Robins Company, Inc. | Method of combating Herpes simplex viruses with lignosulfonates |
JPS54154507A (en) * | 1978-05-22 | 1979-12-05 | Eisai Co Ltd | Inactivating agents for hbs anitgen |
DE3068159D1 (en) * | 1980-03-12 | 1984-07-19 | Mach Walter Dr | Biochemically active ingredient, process for its production and a pharmaceutical preparation that contains this ingredient |
JPS5939411B2 (ja) * | 1980-12-24 | 1984-09-22 | 野田食菌工業株式会社 | 抗動物ウイルス剤 |
JPS57130919A (en) * | 1981-02-06 | 1982-08-13 | Eisai Co Ltd | Lignin-containing virucide |
DE3206911A1 (de) * | 1982-02-26 | 1983-09-15 | Lohmann Tierernährung GmbH, 2190 Cuxhaven | Biochemischer wirkstoff, dessen herstellung und diesen wirkstoff enthaltendes mittel |
DE3707909A1 (de) * | 1987-03-12 | 1988-09-22 | Ruetgerswerke Ag | Niedermolekulare alkalihuminate, verfahren zu ihrer herstellung und verwendung |
US4985249A (en) * | 1987-06-26 | 1991-01-15 | Hiroshi Sakagami | Anti-HIV agents |
US4988799A (en) * | 1987-08-11 | 1991-01-29 | Daishowa Chemicals Inc. | Lignosulfonate based pharmacologic agent with anti-coagulant and anti-thrombotic activity |
JP2602715B2 (ja) * | 1988-04-12 | 1997-04-23 | 日本製紙 株式会社 | 抗ウィルス性医薬用組成物 |
US4935239A (en) * | 1988-04-12 | 1990-06-19 | Sanyo-Kokusaku Pulp Co., Ltd. | Composition for antiviral medicines |
JPH02262524A (ja) * | 1989-03-31 | 1990-10-25 | Shozo Toda | エイズウイルス増殖抑制剤 |
CA1335259C (en) * | 1989-03-31 | 1995-04-18 | Makoto Machida | Composition of spent liquor from pulping process for antiviral medicine |
JPH02286623A (ja) * | 1989-04-27 | 1990-11-26 | Noda Shiyokukin Kogyo Kk | 抗ウイルス物質及びその製法 |
JPH03120223A (ja) * | 1989-10-04 | 1991-05-22 | Sanyo Kokusaku Pulp Co Ltd | 抗ウイルス性医薬用組成物 |
JP2923660B2 (ja) * | 1990-01-06 | 1999-07-26 | 宏 坂上 | ウイルス感染防止剤 |
JP2938916B2 (ja) * | 1990-01-10 | 1999-08-25 | 日本ケミカルリサーチ株式会社 | ヘルペスウィルスの増殖阻害および潜伏感染後の再発阻止剤 |
-
1990
- 1990-05-27 DE DE4017091A patent/DE4017091A1/de not_active Ceased
-
1991
- 1991-05-27 CA CA002084093A patent/CA2084093C/en not_active Expired - Fee Related
- 1991-05-27 EP EP91909678A patent/EP0535001B1/de not_active Expired - Lifetime
- 1991-05-27 JP JP3509179A patent/JP2905289B2/ja not_active Expired - Fee Related
- 1991-05-27 AT AT91909678T patent/ATE110275T1/de not_active IP Right Cessation
- 1991-05-27 WO PCT/DE1991/000450 patent/WO1991018616A1/de active IP Right Grant
- 1991-05-27 AU AU78928/91A patent/AU663684B2/en not_active Ceased
- 1991-05-27 PL PL91296940A patent/PL168266B1/pl not_active IP Right Cessation
- 1991-05-27 RO RO92-01491A patent/RO113430B1/ro unknown
- 1991-05-27 DK DK91909678.4T patent/DK0535001T3/da active
- 1991-05-27 DE DE59102660T patent/DE59102660D1/de not_active Expired - Fee Related
- 1991-05-27 HU HU9203747A patent/HUT68910A/hu unknown
- 1991-05-27 ES ES91909678T patent/ES2065034T3/es not_active Expired - Lifetime
- 1991-05-27 RU RU92016546A patent/RU2104016C1/ru not_active IP Right Cessation
-
1992
- 1992-11-25 FI FI925363A patent/FI925363A/fi not_active Application Discontinuation
- 1992-11-26 NO NO924575A patent/NO306049B1/no not_active IP Right Cessation
- 1992-11-26 BG BG97122A patent/BG61154B1/bg unknown
-
1993
- 1993-01-27 US US07/969,208 patent/US5554596A/en not_active Expired - Lifetime
-
1995
- 1995-06-05 US US08/465,351 patent/US5698524A/en not_active Expired - Lifetime
- 1995-06-16 HU HU95P/P00238P patent/HU211541A9/hu unknown
Also Published As
Publication number | Publication date |
---|---|
WO1991018616A1 (de) | 1991-12-12 |
NO924575L (no) | 1993-01-12 |
BG97122A (bg) | 1993-12-24 |
US5554596A (en) | 1996-09-10 |
JP2905289B2 (ja) | 1999-06-14 |
EP0535001B1 (de) | 1994-08-24 |
HU9203747D0 (en) | 1993-03-29 |
HU211541A9 (en) | 1995-12-28 |
FI925363A0 (fi) | 1992-11-25 |
RU2104016C1 (ru) | 1998-02-10 |
EP0535001A1 (de) | 1993-04-07 |
AU7892891A (en) | 1991-12-31 |
AU663684B2 (en) | 1995-10-19 |
FI925363A (fi) | 1992-11-25 |
NO306049B1 (no) | 1999-09-13 |
DE4017091A1 (de) | 1991-11-28 |
NO924575D0 (no) | 1992-11-26 |
DE59102660D1 (de) | 1994-09-29 |
PL168266B1 (pl) | 1996-01-31 |
BG61154B1 (bg) | 1997-01-31 |
ATE110275T1 (de) | 1994-09-15 |
US5698524A (en) | 1997-12-16 |
CA2084093C (en) | 2002-10-22 |
RO113430B1 (ro) | 1998-07-30 |
HUT68910A (en) | 1995-08-28 |
CA2084093A1 (en) | 1991-11-28 |
DK0535001T3 (da) | 1995-02-20 |
JPH05507270A (ja) | 1993-10-21 |
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