ES2063107T3 - Nuevas pirido (2,3-d) pirimidinas substituidas. - Google Patents

Nuevas pirido (2,3-d) pirimidinas substituidas.

Info

Publication number
ES2063107T3
ES2063107T3 ES89123894T ES89123894T ES2063107T3 ES 2063107 T3 ES2063107 T3 ES 2063107T3 ES 89123894 T ES89123894 T ES 89123894T ES 89123894 T ES89123894 T ES 89123894T ES 2063107 T3 ES2063107 T3 ES 2063107T3
Authority
ES
Spain
Prior art keywords
pirido
new
substituted pyrimidines
saponificada
pirimidina
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89123894T
Other languages
English (en)
Inventor
Walter Dr Hubsch
Rolf Dr Angerbauer
Peter Dr Fey
Thomas Dr Philipps
Hilmar Dr Bischoff
Dieter Dr Petzinna
Delf Dr Schmidt
Gunter Dr Thomas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3900363A external-priority patent/DE3900363A1/de
Priority claimed from IT8921215A external-priority patent/IT8921215A0/it
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2063107T3 publication Critical patent/ES2063107T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

EL INVENTO SE REFIERE A UN NUEVO PURIDO (2,3-D) PIRIDIMINA SUSTITUIDA; TRATA DE UN PROCEDIMIENTO PARA SU OBTENCION QUE CONSISTE EN REDUCIR LA PIRIDA (2,3-D) PIRIDIMINA SUSTITUIDA CON UN RESTO CETONA; SAPONIFICAR LA PIRIDO (2,3-D) PIRIMIDINA REDUCIDA; CIDIZAR LA PIRIDO (2,3-D) PIRIMIDINA SAPONIFICADA E HIDROGENAR LA PIRIDO (2,3-D) PIRIMIDINA SAPONIFICADA Y DESCRIBE SU APLICACION COMO MATERIA ACTIVA EN MEDICAMENTO.
ES89123894T 1989-01-07 1989-12-23 Nuevas pirido (2,3-d) pirimidinas substituidas. Expired - Lifetime ES2063107T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3900363A DE3900363A1 (de) 1989-01-07 1989-01-07 Neue substituierte pyrido(2,3,-d)pyrimidine
IT8921215A IT8921215A0 (it) 1989-07-18 1989-07-18 Pirido(2,3 d)pirimidine sostituite.

Publications (1)

Publication Number Publication Date
ES2063107T3 true ES2063107T3 (es) 1995-01-01

Family

ID=25876617

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89123894T Expired - Lifetime ES2063107T3 (es) 1989-01-07 1989-12-23 Nuevas pirido (2,3-d) pirimidinas substituidas.

Country Status (17)

Country Link
US (1) US5075311A (es)
EP (1) EP0378850B1 (es)
JP (1) JPH02247179A (es)
KR (1) KR900011768A (es)
CN (1) CN1043938A (es)
AU (1) AU618158B2 (es)
CA (1) CA2007233A1 (es)
DE (1) DE58907412D1 (es)
DK (1) DK3290A (es)
ES (1) ES2063107T3 (es)
FI (1) FI900038A (es)
HU (1) HUT53640A (es)
IE (1) IE900058L (es)
IL (1) IL92970A (es)
NO (1) NO895217L (es)
NZ (1) NZ232013A (es)
PT (1) PT92793A (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145959A (en) * 1989-07-18 1992-09-08 Bayer Aktiengesellschaft Substituted pyrido (2,3-d) pyrimidines as intermediates
DE4035479A1 (de) * 1990-11-08 1992-05-14 Basf Ag Substituierte pyrido (2,3-d)pyrimidin-2,4(1h,3h)-dione
AR008789A1 (es) 1996-07-31 2000-02-23 Bayer Corp Piridinas y bifenilos substituidos
NZ502642A (en) * 1997-07-03 2002-06-28 Du Pont Pharm Co Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders
US6124463A (en) * 1998-07-02 2000-09-26 Dupont Pharmaceuticals Benzimidazoles as corticotropin release factor antagonists
US6365589B1 (en) 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
US7420059B2 (en) * 2003-11-20 2008-09-02 Bristol-Myers Squibb Company HMG-CoA reductase inhibitors and method
WO2006019965A2 (en) * 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
EP2266984A1 (en) * 2009-06-26 2010-12-29 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Pyrido[2,3-d]pyrimidines as Wnt antagonists for treatment of cancer and arthritis
CN108164517A (zh) * 2018-02-12 2018-06-15 李化绪 (2-甲基环己烷-1-基)亚氨基类化合物及其在高脂血症药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE114027C (es) *
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
GR69216B (es) * 1979-06-15 1982-05-07 Merck & Co Inc
US4613610A (en) * 1984-06-22 1986-09-23 Sandoz Pharmaceuticals Corp. Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives
US4761419A (en) * 1987-12-07 1988-08-02 Warner-Lambert Company 6-(((substituted)quinolinyl)ethyl)-and ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis

Also Published As

Publication number Publication date
EP0378850A2 (de) 1990-07-25
CA2007233A1 (en) 1990-07-07
EP0378850B1 (de) 1994-04-06
NO895217L (no) 1990-07-09
US5075311A (en) 1991-12-24
FI900038A0 (fi) 1990-01-04
HU900049D0 (en) 1990-03-28
NO895217D0 (no) 1989-12-22
DE58907412D1 (de) 1994-05-11
CN1043938A (zh) 1990-07-18
IL92970A0 (en) 1990-09-17
IL92970A (en) 1994-01-25
AU618158B2 (en) 1991-12-12
EP0378850A3 (de) 1991-09-11
HUT53640A (en) 1990-11-28
DK3290A (da) 1990-07-08
AU4698889A (en) 1990-07-12
NZ232013A (en) 1991-11-26
KR900011768A (ko) 1990-08-02
PT92793A (pt) 1990-07-31
DK3290D0 (da) 1990-01-05
FI900038A (fi) 1990-07-08
IE900058L (en) 1990-07-07
JPH02247179A (ja) 1990-10-02

Similar Documents

Publication Publication Date Title
ES2063107T3 (es) Nuevas pirido (2,3-d) pirimidinas substituidas.
ES2045229T3 (es) Pirrolidinas 1,3-disubstituidas.
ES2054649T3 (es) 2-aminotetralinas basicas substituidas.
ES2071306T3 (es) El uso de tensioactivos fluorados solubles para la preparacion de formulaciones aerosoles dosificadas.
BR9611429A (pt) Resposta intensificada ao sinal de umidade em artigos absorventes
MX9308013A (es) 4-fenil-piridonas y 4-fenil-2-fenil-2-alcoxipiridinas sustituidas, procedimiento para su preparacion y medicamentos que los contienen.
GB9504265D0 (en) Corticosteroid-containing pharmaceutical composition
DE69325374T2 (de) Dehnbare absorbierende struktur
DE69111077D1 (de) Chinazolinderivate um die antitumorwirkung zu verbessern.
BR0007919A (pt) Composição purina 2,6,9-trisubstituìda
ES2170250T3 (es) Articulo absorbente desechable que tiene una lamina superior con locion y que contiene un emoliente y un agente inmovilizante de poliester de poliol.
ES2174968T3 (es) Preparacion de microcapsulas huecas.
IL71558A (en) Divisible tablet with delayed release of active substance and its production
ATE10342T1 (de) Sanitaere hygienemittel, die der aufnahme harn und blut enthaltender sekrete dienen, mit geruchsverhindernden eigenschaften.
MX9400434A (es) Potenciamiento de temozolomida en celulas de tumores humanos.
AR003176A1 (es) Una composicion farmaceutica para inhibir el crecimiento de cancer
ES2056288T3 (es) Absorbente de oxigeno.
GT198277855A (es) Preparacion de premezclas de piensos para animales
ES2065647T3 (es) Empleo cosmetico de una composicion que tiene una actividad antieritematosa.
PT727996E (pt) Formulacoes de febbendazol
SV1996000008A (es) Uso de amidas de acido fenilciclohexilcarboxilicos
ES2172095T3 (es) Utilizacion de sulfitos y metabisulfitos, para la fabricacion de composiciones cosmeticas o farmaceuticas, particularmente en dermatologia, con efecto inhibidor de la melanogenesis o con actividad despigmentante.
DZ3208A1 (fr) Comprimes faiblement doses et procédé de préparation.
MX9303600A (es) Derivados de los acidos fenilpropionico y -cinamico sustituidos por imidazolilo, procedimiento para su obtencion y medicamentos que los contienen.
ES556437A0 (es) Procedimiento para preparar un agente que contiene tirosina o un derivado de tirosina como sustancia activa para mejorar la fecundidad de mamiferos.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 378850

Country of ref document: ES