ES2062442T3 - Nuevos derivados de tetrahidro-5,6,7,8 naftalenol-1, su procedimiento de preparacion y su utilizacion como agentes antioxidantes en composiciones cosmeticas y farmaceuticas que los contienen. - Google Patents

Nuevos derivados de tetrahidro-5,6,7,8 naftalenol-1, su procedimiento de preparacion y su utilizacion como agentes antioxidantes en composiciones cosmeticas y farmaceuticas que los contienen.

Info

Publication number
ES2062442T3
ES2062442T3 ES90401641T ES90401641T ES2062442T3 ES 2062442 T3 ES2062442 T3 ES 2062442T3 ES 90401641 T ES90401641 T ES 90401641T ES 90401641 T ES90401641 T ES 90401641T ES 2062442 T3 ES2062442 T3 ES 2062442T3
Authority
ES
Spain
Prior art keywords
radical
pharmaceutical compositions
cosmetic
alkyl radical
naftalenol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90401641T
Other languages
English (en)
Inventor
Jean Maignan
Gerard Malle
Andre Deflandre
Gerard Lang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Application granted granted Critical
Publication of ES2062442T3 publication Critical patent/ES2062442T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/10—Quinones the quinoid structure being part of a condensed ring system containing two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • C07C65/26—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic containing rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)

Abstract

DERIVADOS DE TETRAHIDRO-5,6,7,8-NAFTALENOL-1. ESTOS DERIVADOS RESPONDEN A LA FORMULA GENERAL (I), EN LA QUE R1, R2, R3 Y R4 REPRESENTAN UN RADICAL ALQUILO INFERIOR; R5 Y R6 REPRESENTAN UN ATOMO DE HIDROGENO O UN RADICAL ALQUILO INFERIOR; R ES UN ATOMO DE HIDROGENO, UN RADICAL ALQUILO C1-C18, UN RADICAL ALQUILO C2-C18 SUSTITUIDO POR UNO O VARIOS HIDROXILO(S), UN RADICAL ALQUENILO C3-C18, UN RADICAL ACILO C2-C18, UN RADICAL BENCILO, UN RADICAL BENZOILO, UN RADICAL CARBOXILO Y LAS SALES CARBOXILICAS DE UN METAL ALCALINO O ALCALINOTERREO O DE UNA AMINA ORGANICA. ESTOS DERIVADOS ENCUENTRAN APLICACION COMO AGENTES OXIDANTES EN COMPOSICIONES COSMETICAS Y EN COMPOSICIONES FARMACEUTICAS PARA EL TRATAMIENTO PREVENTIVO DE INFLAMACIONES Y DE ALERGIAS CUTANEAS O DE CIERTAS FORMAS DE CANCER.
ES90401641T 1989-06-13 1990-06-13 Nuevos derivados de tetrahidro-5,6,7,8 naftalenol-1, su procedimiento de preparacion y su utilizacion como agentes antioxidantes en composiciones cosmeticas y farmaceuticas que los contienen. Expired - Lifetime ES2062442T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8907805A FR2648131B1 (fr) 1989-06-13 1989-06-13 Nouveaux derives de tetrahydro -5,6,7,8 naphtalenol-1, leur procede de preparation et leur utilisation en tant qu'agents antioxydants dans des compositions cosmetiques et pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
ES2062442T3 true ES2062442T3 (es) 1994-12-16

Family

ID=9382658

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90401641T Expired - Lifetime ES2062442T3 (es) 1989-06-13 1990-06-13 Nuevos derivados de tetrahidro-5,6,7,8 naftalenol-1, su procedimiento de preparacion y su utilizacion como agentes antioxidantes en composiciones cosmeticas y farmaceuticas que los contienen.

Country Status (9)

Country Link
US (2) US5043482A (es)
EP (1) EP0404640B1 (es)
JP (1) JPH0363240A (es)
AT (1) ATE101590T1 (es)
AU (1) AU627036B2 (es)
CA (1) CA2018959A1 (es)
DE (1) DE69006647T2 (es)
ES (1) ES2062442T3 (es)
FR (1) FR2648131B1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4033568A1 (de) * 1990-10-22 1992-04-23 Henkel Kgaa Bicyclische verbindungen mit antiseborrhoischer wirkung
DE19814084B4 (de) * 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
DE19850474A1 (de) 1998-11-02 2000-05-04 Varta Geraetebatterie Gmbh Verfahren zur Herstellung einer positiven Elektrode für ein alkalisches Primärelement
EP1515688B1 (fr) 2002-06-11 2013-07-24 L'Oréal Utilisation d'un complexe salen-manganèse comme agent protecteur des mélanocytes du follicule pileux et applications cosmétiques
FR2840531B1 (fr) * 2002-06-11 2004-10-29 Oreal Composition cosmetique comprenant un agent mimetique de l'activite de la dopachrome tautomerase (trp-2) pour lutter contre la canitie
DE10234673B4 (de) * 2002-07-30 2007-08-16 Schwarz Pharma Ag Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
US8211462B2 (en) * 2002-07-30 2012-07-03 Ucb Pharma Gmbh Hot-melt TTS for administering rotigotine
DE10261696A1 (de) 2002-12-30 2004-07-15 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3426358A (en) * 1965-11-19 1969-02-04 Hooker Chemical Corp Alkylation of phenols
US3830854A (en) * 1970-01-08 1974-08-20 Allied Chem Substituted 5,8-dimethyl-5,6,7,8-tetrahydro-1-naphthols
CA979912A (en) * 1970-06-22 1975-12-16 Frederic P. Hauck Tetrahydronaphthyloxyaminopropanols and related compounds
FR2246528A1 (en) * 1973-10-04 1975-05-02 Roussel Uclaf Di-substd hydroquinone and esterified derivs as antioxidants - esp for use in cosmetic prepns to reduce skin aging
DE3434944A1 (de) * 1984-09-22 1986-04-03 Basf Ag, 6700 Ludwigshafen L-substituierte tetralinderivate, ihre herstellung und verwendung

Also Published As

Publication number Publication date
US5043482A (en) 1991-08-27
FR2648131B1 (fr) 1991-10-18
DE69006647D1 (de) 1994-03-24
CA2018959A1 (fr) 1990-12-13
JPH0363240A (ja) 1991-03-19
US5158977A (en) 1992-10-27
AU5695390A (en) 1990-12-20
ATE101590T1 (de) 1994-03-15
EP0404640A1 (fr) 1990-12-27
AU627036B2 (en) 1992-08-13
DE69006647T2 (de) 1994-05-26
FR2648131A1 (fr) 1990-12-14
EP0404640B1 (fr) 1994-02-16

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