YU47914B - Derivati 9-alfa-hidroksi-3-okso-4,24(25)-stigmastadien-26-ske kiseline i postupak za dobivanje istih - Google Patents
Derivati 9-alfa-hidroksi-3-okso-4,24(25)-stigmastadien-26-ske kiseline i postupak za dobivanje istihInfo
- Publication number
- YU47914B YU47914B YU92390A YU92390A YU47914B YU 47914 B YU47914 B YU 47914B YU 92390 A YU92390 A YU 92390A YU 92390 A YU92390 A YU 92390A YU 47914 B YU47914 B YU 47914B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- stigmastadien
- oxo
- hydroxy
- pct
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Derivati 9-alfa-hidroksi-3-okso-4,24(25)-stigmastadien-26-ske kiseline opšte formule I gde M označava vodonik, C1-4 alkil ili farmaceutski prihvatljiv katjon. Postupak za dobivanje derivata 9-alfa -hidroksi-3-okso-4,24(25)-stigmastadien-26-ske kiseline opšte formule I, gde M označava vodonik, C1-4 alkil ili farmaceutski prihvatljiv katjon, na značen time, što obuhvata fermentaciju beta-si-tosterola ili sterolne smeše koja sadrži beta-sitosterol biljnog porekla potapanjem aerobične kulture Mycobacterium sp. BCS-394 deponovane pod brojem NCAIM B(P) 001038 ili njenog mutanta u hranljivu sredinu koja sadrži iskoristive izvore azota i ugljenika kao i mineralne soli, ako se želi, izolovanje iz čorbe jedinjenja opšte formule I, gde M označava H i/ili metil grupu, i ako se želi, prevodjenje jedinjenja opšte formule I gde M označava H u jedinjenje formule I gde M je C1-4 alkil grupa ili farmaceutski prihvatljiv katjon. Prijava sadrži još 1 nezavisan i 4 zavisna zahteva.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HR920777A HRP920777A2 (en) | 1989-05-11 | 1992-10-01 | New -9alpha-hydroxy-3-oxo-4,24(25)-stigmastadien-26-oic acid derivatives, the process for the preparation thereof and pharmaceutical compositions containing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU235989 | 1989-05-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
YU92390A YU92390A (en) | 1991-10-31 |
YU47914B true YU47914B (sh) | 1996-05-20 |
Family
ID=10958990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU92390A YU47914B (sh) | 1989-05-11 | 1990-05-11 | Derivati 9-alfa-hidroksi-3-okso-4,24(25)-stigmastadien-26-ske kiseline i postupak za dobivanje istih |
Country Status (17)
Country | Link |
---|---|
US (1) | US5112815A (sh) |
EP (1) | EP0424504B1 (sh) |
KR (1) | KR920701232A (sh) |
CN (1) | CN1048857A (sh) |
AT (1) | ATE104313T1 (sh) |
AU (1) | AU638993B2 (sh) |
DE (1) | DE69008103T2 (sh) |
DK (1) | DK0424504T3 (sh) |
ES (1) | ES2055429T3 (sh) |
FI (1) | FI910159A0 (sh) |
GR (1) | GR1002174B (sh) |
HR (1) | HRP920777A2 (sh) |
IL (1) | IL94272A (sh) |
NZ (1) | NZ233657A (sh) |
WO (1) | WO1990013559A1 (sh) |
YU (1) | YU47914B (sh) |
ZA (1) | ZA903628B (sh) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995000158A1 (en) * | 1993-06-25 | 1995-01-05 | Bio-Sphere Technology | Dietary supplement incorporating beta-sitosterol and pectin |
JP3873097B2 (ja) * | 1997-11-06 | 2007-01-24 | 独立行政法人理化学研究所 | 抗肥満剤及び脂質代謝改善剤 |
US6531462B2 (en) | 1997-11-06 | 2003-03-11 | Riken | Medicament for treating obesity and improving lipid metabolism |
US5952393A (en) * | 1998-02-12 | 1999-09-14 | Sorkin, Jr.; Harlan Lee | Composition for reducing serum cholesterol levels |
CA2395447A1 (en) | 2000-01-28 | 2001-08-02 | Robert Joseph Sarama | Palatable arginine compounds and uses thereof for cardiovascular health |
US20030045473A1 (en) * | 2002-07-19 | 2003-03-06 | Sarama Robert Joseph | Compositions, kits, and methods for cardiovascular health |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4062880A (en) * | 1976-04-30 | 1977-12-13 | The Upjohn Company | 9α-Hydroxy-bis-nor-cholanic acid |
US4214051A (en) * | 1977-10-21 | 1980-07-22 | The Upjohn Company | Process for preparing 9α-OH BN acid methyl ester |
US4429041A (en) * | 1981-05-11 | 1984-01-31 | The Upjohn Company | Process of producing 9-hydroxy-3-oxo-4,17(20)-pregnadiene-20-carboxylic acid |
US4425429A (en) * | 1981-07-24 | 1984-01-10 | The Upjohn Company | Composition of matter and process |
US4755463A (en) * | 1982-05-25 | 1988-07-05 | Wisconsin Alumni Research Foundation | Process for preparing steroids |
-
1990
- 1990-05-03 IL IL9427290A patent/IL94272A/en not_active IP Right Cessation
- 1990-05-10 AT AT90907364T patent/ATE104313T1/de not_active IP Right Cessation
- 1990-05-10 ES ES90907364T patent/ES2055429T3/es not_active Expired - Lifetime
- 1990-05-10 US US07/635,623 patent/US5112815A/en not_active Expired - Fee Related
- 1990-05-10 DE DE69008103T patent/DE69008103T2/de not_active Expired - Fee Related
- 1990-05-10 DK DK90907364.5T patent/DK0424504T3/da active
- 1990-05-10 WO PCT/HU1990/000033 patent/WO1990013559A1/en active IP Right Grant
- 1990-05-10 AU AU56363/90A patent/AU638993B2/en not_active Ceased
- 1990-05-10 EP EP90907364A patent/EP0424504B1/en not_active Expired - Lifetime
- 1990-05-10 KR KR1019910700031A patent/KR920701232A/ko not_active IP Right Cessation
- 1990-05-11 YU YU92390A patent/YU47914B/sh unknown
- 1990-05-11 NZ NZ233657A patent/NZ233657A/en unknown
- 1990-05-11 CN CN90104386A patent/CN1048857A/zh active Pending
- 1990-05-11 GR GR900100356A patent/GR1002174B/el unknown
- 1990-05-11 ZA ZA903628A patent/ZA903628B/xx unknown
-
1991
- 1991-01-11 FI FI910159A patent/FI910159A0/fi not_active Application Discontinuation
-
1992
- 1992-10-01 HR HR920777A patent/HRP920777A2/hr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL94272A (en) | 1994-04-12 |
EP0424504B1 (en) | 1994-04-13 |
HRP920777A2 (en) | 1994-08-31 |
KR920701232A (ko) | 1992-08-11 |
EP0424504A1 (en) | 1991-05-02 |
ATE104313T1 (de) | 1994-04-15 |
NZ233657A (en) | 1992-03-26 |
AU5636390A (en) | 1990-11-29 |
IL94272A0 (en) | 1991-03-10 |
ES2055429T3 (es) | 1994-08-16 |
DE69008103T2 (de) | 1994-07-28 |
GR900100356A (el) | 1991-10-10 |
DK0424504T3 (da) | 1994-05-16 |
FI910159A0 (fi) | 1991-01-11 |
YU92390A (en) | 1991-10-31 |
ZA903628B (en) | 1991-04-24 |
CN1048857A (zh) | 1991-01-30 |
DE69008103D1 (de) | 1994-05-19 |
GR1002174B (en) | 1996-03-07 |
WO1990013559A1 (en) | 1990-11-15 |
US5112815A (en) | 1992-05-12 |
AU638993B2 (en) | 1993-07-15 |
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