ES2062135T3 - Derivados del acido tienilacetico, procedimiento para su obtencion, su empleo, asi como medicamentos que contienen este y su obtencion. - Google Patents

Derivados del acido tienilacetico, procedimiento para su obtencion, su empleo, asi como medicamentos que contienen este y su obtencion.

Info

Publication number
ES2062135T3
ES2062135T3 ES90104323T ES90104323T ES2062135T3 ES 2062135 T3 ES2062135 T3 ES 2062135T3 ES 90104323 T ES90104323 T ES 90104323T ES 90104323 T ES90104323 T ES 90104323T ES 2062135 T3 ES2062135 T3 ES 2062135T3
Authority
ES
Spain
Prior art keywords
obtaining
well
denotes
derivatives
tenylacetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90104323T
Other languages
English (en)
Inventor
Rudi Dr Beyerle
Karl Dr Schonafinger
Ursula Dr Schindler
Bernd Dr Jablonka
Jeffery Dr Troke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Cassella Farbwerke Mainkur AG
Original Assignee
Cassella AG
Cassella Farbwerke Mainkur AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cassella AG, Cassella Farbwerke Mainkur AG filed Critical Cassella AG
Application granted granted Critical
Publication of ES2062135T3 publication Critical patent/ES2062135T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

EL PRESENTE INVENTO CONCIERNE A DERIVADOS DEL ACIDO TIENILACETICO, DE FORMULA GENERAL I (FORMULA), EN LA QUE: X SIGNIFICA -O- O -NH-; R1 ES HIDROGENO, EL GRUPO -CH2-CO-R3 O BIEN EL GRUPO -CO-CH2-NH2; R2 ES HIDROGENO, UN ALQUILO DE C1-C4 O UN RESTO R1 Y R3 ES (C1-C4)-ALCOXI; HIDROXI O AMINO, NO PUDIENDO SER R1 Y R2 A LA VEZ HIDROGENO CUANDO X SIGNIFIQUE O. TAMBIEN CONCIERNE A SUS SALES TOLERABLES EN FARMACIA, AL PROCEDIMIENTO DE PRODUCCION DE AQUELLOS, A SU UTILIZACION, ASI COMO A LOS MEDICAMENTOS QUE LOS CONTIENEN Y A SU PRODUCCION.
ES90104323T 1989-03-16 1990-03-07 Derivados del acido tienilacetico, procedimiento para su obtencion, su empleo, asi como medicamentos que contienen este y su obtencion. Expired - Lifetime ES2062135T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3908547A DE3908547A1 (de) 1989-03-16 1989-03-16 Thienylessigsaeurederivate, verfahren zu ihrer herstellung, ihre verwendung sowie diese enthaltende arzneimittel und deren herstellung

Publications (1)

Publication Number Publication Date
ES2062135T3 true ES2062135T3 (es) 1994-12-16

Family

ID=6376450

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90104323T Expired - Lifetime ES2062135T3 (es) 1989-03-16 1990-03-07 Derivados del acido tienilacetico, procedimiento para su obtencion, su empleo, asi como medicamentos que contienen este y su obtencion.

Country Status (13)

Country Link
US (1) US5015659A (es)
EP (1) EP0387677B1 (es)
JP (1) JP2930214B2 (es)
KR (1) KR0150002B1 (es)
AT (1) ATE102939T1 (es)
CA (1) CA2012313C (es)
DD (1) DD292908A5 (es)
DE (2) DE3908547A1 (es)
ES (1) ES2062135T3 (es)
HU (1) HU204808B (es)
IL (1) IL93748A0 (es)
PT (1) PT93456A (es)
ZA (1) ZA901981B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT402925B (de) * 1995-05-26 1997-09-25 Chemie Linz Gmbh L-aspartyl-l-thienylalaninmethylester, verfahren zu deren herstellung und verwendung als süssstoff
DE19622354A1 (de) * 1996-06-04 1997-12-11 Bayer Ag Halogenthiophen-Derivate
EP2066619A2 (en) * 2006-11-02 2009-06-10 Arete Therapeutics, INC. Soluble epoxide hydrolase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2351952A1 (fr) * 1975-09-12 1977-12-16 Nobel Hoechst Chimie Procede de fabrication de derives n-acyles de glycines a substituees par des radicaux aromatiques
EP0067641A3 (en) * 1981-06-17 1983-03-09 Beecham Group Plc Amino acids
DE3132882A1 (de) * 1981-08-20 1983-03-03 Cassella Ag, 6000 Frankfurt Neue piperazinone, ihre herstellung und verwendung

Also Published As

Publication number Publication date
JP2930214B2 (ja) 1999-08-03
HU204808B (en) 1992-02-28
ATE102939T1 (de) 1994-04-15
ZA901981B (en) 1990-11-28
IL93748A0 (en) 1990-12-23
DE3908547A1 (de) 1990-09-20
KR0150002B1 (ko) 1998-10-15
DD292908A5 (de) 1991-08-14
EP0387677A2 (de) 1990-09-19
KR900014356A (ko) 1990-10-23
CA2012313C (en) 1998-10-06
DE59004965D1 (de) 1994-04-21
EP0387677B1 (de) 1994-03-16
HUT53096A (en) 1990-09-28
CA2012313A1 (en) 1990-09-16
HU901424D0 (en) 1990-06-28
US5015659A (en) 1991-05-14
EP0387677A3 (en) 1990-12-05
PT93456A (pt) 1990-11-07
JPH02273669A (ja) 1990-11-08

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