ES2062014T3 - Carbonatos de 3-desmetiltiocolchicina y analogos n-acilados. - Google Patents
Carbonatos de 3-desmetiltiocolchicina y analogos n-acilados.Info
- Publication number
- ES2062014T3 ES2062014T3 ES89308341T ES89308341T ES2062014T3 ES 2062014 T3 ES2062014 T3 ES 2062014T3 ES 89308341 T ES89308341 T ES 89308341T ES 89308341 T ES89308341 T ES 89308341T ES 2062014 T3 ES2062014 T3 ES 2062014T3
- Authority
- ES
- Spain
- Prior art keywords
- desmetiltiocolchicina
- carbonates
- acylated analogs
- alkyl
- analogs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/41—Y being a hydrogen or an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
LA PRESENTE INVENCION SE REFIERE A ESTERES DE 3-DEMETILTIOCOLQUICINA Y SUS ANALOGOS N-ACILICOS, QUE TIENEN LA FORMULA: (FIG. A), DONDE R ES O-CO-ALQUILO, O-CO-CH2OALQUILO, O-CO-FENILO, O-COOALQUILO; TENIENDO EL GRUPO ALQUILO DE 1-4 ATOMOS DE CARBONO Y REPRESENTANDO EL GRUPO AC Y SUS HOMOLOGOS MAS ALTOS, BENZOILO, ALCOXIACETILO O HALOACETILO. LA INVENCION SE REFIERE, ADEMAS, A PROCEDIMIENTOS PARA PREPARAR ESTOS COMPUESTOS ESTERES, A SUS COMPOSICIONES FARMACEUTICAS Y METODOS PARA TRATAR ENFERMEDADES TALES COMO GOTA, FIEBRE MEDITERRANEA Y DESORDENES DE HIGADO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23590788A | 1988-08-24 | 1988-08-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2062014T3 true ES2062014T3 (es) | 1994-12-16 |
Family
ID=22887351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89308341T Expired - Lifetime ES2062014T3 (es) | 1988-08-24 | 1989-08-17 | Carbonatos de 3-desmetiltiocolchicina y analogos n-acilados. |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0356137B1 (es) |
JP (1) | JPH02142765A (es) |
AT (1) | ATE113273T1 (es) |
AU (1) | AU618395B2 (es) |
CA (1) | CA1338432C (es) |
DE (1) | DE68919025T2 (es) |
DK (1) | DK416289A (es) |
ES (1) | ES2062014T3 (es) |
FI (1) | FI95461C (es) |
ZA (1) | ZA896411B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1270124B (it) * | 1994-10-05 | 1997-04-28 | Indena Spa | Derivati della colchicina e loro impiego terapeutico |
IT1291550B1 (it) * | 1997-04-11 | 1999-01-11 | Indena Spa | Derivati della colchicina e della tiocolchicina ad attivita' antinfiammatoria e miorilassante |
CN102448930A (zh) | 2009-05-27 | 2012-05-09 | 共有药物有限公司 | 硫代秋水仙碱衍生物、其制造方法和使用方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US235907A (en) * | 1880-12-28 | sqhlimp | ||
FR1099138A (fr) * | 1954-02-10 | 1955-08-30 | Roussel Uclaf | Thiodérivés tropoloniques de la colchicine et leur procédé d'obtention |
US2820029A (en) * | 1954-02-10 | 1958-01-14 | U C L A F | New thio-derivatives of colchiceine compounds and a process of making same |
-
1989
- 1989-08-17 EP EP89308341A patent/EP0356137B1/en not_active Expired - Lifetime
- 1989-08-17 ES ES89308341T patent/ES2062014T3/es not_active Expired - Lifetime
- 1989-08-17 DE DE68919025T patent/DE68919025T2/de not_active Expired - Fee Related
- 1989-08-17 AT AT89308341T patent/ATE113273T1/de active
- 1989-08-22 ZA ZA896411A patent/ZA896411B/xx unknown
- 1989-08-23 FI FI893955A patent/FI95461C/fi not_active IP Right Cessation
- 1989-08-23 DK DK416289A patent/DK416289A/da not_active Application Discontinuation
- 1989-08-23 AU AU40191/89A patent/AU618395B2/en not_active Ceased
- 1989-08-24 JP JP1218416A patent/JPH02142765A/ja active Pending
- 1989-08-24 CA CA000609341A patent/CA1338432C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK416289A (da) | 1990-02-25 |
FI95461B (fi) | 1995-10-31 |
AU4019189A (en) | 1990-03-01 |
DK416289D0 (da) | 1989-08-23 |
CA1338432C (en) | 1996-07-02 |
AU618395B2 (en) | 1991-12-19 |
EP0356137A2 (en) | 1990-02-28 |
EP0356137A3 (en) | 1990-11-07 |
JPH02142765A (ja) | 1990-05-31 |
ATE113273T1 (de) | 1994-11-15 |
EP0356137B1 (en) | 1994-10-26 |
DE68919025D1 (de) | 1994-12-01 |
DE68919025T2 (de) | 1995-03-02 |
FI893955A0 (fi) | 1989-08-23 |
ZA896411B (en) | 1990-05-30 |
FI95461C (fi) | 1996-02-12 |
FI893955A (fi) | 1990-02-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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