ES2061682T3 - Cisteina proteinasas, produccion y uso. - Google Patents
Cisteina proteinasas, produccion y uso.Info
- Publication number
- ES2061682T3 ES2061682T3 ES88309842T ES88309842T ES2061682T3 ES 2061682 T3 ES2061682 T3 ES 2061682T3 ES 88309842 T ES88309842 T ES 88309842T ES 88309842 T ES88309842 T ES 88309842T ES 2061682 T3 ES2061682 T3 ES 2061682T3
- Authority
- ES
- Spain
- Prior art keywords
- production
- enzymes
- disclosed
- distinct
- cysteine proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/63—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/13—Burn treatment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
Abstract
UNA CISTEINA - PROTEINASA CARACTERIZADA PORQUE ES INMUNOLOGICAMENTE DISTINTA, TIENE UNA MASA MOLECULAR DE ALREDEDOR DE 25000 Y UNA CARGA NETA DISTINTA. TALES ENZIMAS SON ANANAIN Y COMOSAIN QUE SE PUEDEN DISTINGUIR POR SUS ESPECIFICIDADES PARA LAGUNOS SUSTRATOS SINTETICOS. TAMBIEN SE INCLUYE UN PROCESO PARA SU PRODUCCION QUE COMPRENDE LA SEPARACION DE MATERIAL DE UNA PLANTA DE ELABORACION DE PINA Y SU PURIFICACION. ESTAS ENZIMAS SE PUEDEN EMPLEAR EN EL DESBRIDAMIENTO DE TEJIDOS DE COSTRAS DE HERIDAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878724728A GB8724728D0 (en) | 1987-10-22 | 1987-10-22 | Cysteine proteinase |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2061682T3 true ES2061682T3 (es) | 1994-12-16 |
Family
ID=10625712
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88309842T Expired - Lifetime ES2061682T3 (es) | 1987-10-22 | 1988-10-20 | Cisteina proteinasas, produccion y uso. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5106621A (es) |
EP (1) | EP0313346B1 (es) |
JP (1) | JP2644006B2 (es) |
AT (1) | ATE102248T1 (es) |
AU (1) | AU628790B2 (es) |
CA (1) | CA1319121C (es) |
DE (1) | DE3888082T2 (es) |
DK (1) | DK589388A (es) |
ES (1) | ES2061682T3 (es) |
GB (1) | GB8724728D0 (es) |
IL (1) | IL88078A (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8821049D0 (en) * | 1988-09-08 | 1988-10-05 | Health Lab Service Board | Method & composition for treatment & prevention of viral infections |
IL105699A0 (en) * | 1992-06-26 | 1993-09-22 | Genzyme Corp | Hydrophilic creams for delivery of therapeutic agents |
JP3221997B2 (ja) * | 1993-03-26 | 2001-10-22 | 株式会社東芝 | 画像処理装置 |
US5387517A (en) * | 1994-03-23 | 1995-02-07 | Ethicon, Inc. | Thiol activated protease from stem bromelain for treating devitalized tissue |
US5935572A (en) * | 1997-01-10 | 1999-08-10 | Collaborative Laboratories, Inc. | Composition containing protease separate from glycosidase for removing nits in treating lice infestation |
CN1252101A (zh) | 1997-02-25 | 2000-05-03 | 科特克斯(英国)有限公司 | 菠萝蛋白酶成分 |
WO1998038319A1 (en) * | 1997-02-25 | 1998-09-03 | Cortecs (Uk) Limited | Component of bromelain |
US20020102253A1 (en) | 1997-02-25 | 2002-08-01 | Mynott Tracey Lehanne | Component of bromelain |
US6548556B2 (en) | 2000-12-27 | 2003-04-15 | Healthpoint, Ltd. | Stable enzymatic wound debrider |
US7364565B2 (en) | 2001-07-27 | 2008-04-29 | Ramot At Tel Aviv University Ltd. | Controlled enzymatic removal and retrieval of cells |
AU2003222418B2 (en) * | 2002-04-23 | 2008-10-23 | Mediwound, Ltd. | Apparatus and methods for enzymatic escharotomy in burn induced compartment syndrome |
AU2003287105A1 (en) * | 2002-10-10 | 2004-05-04 | Verenium Corporation | Proteases, nucleic acids encoding them and methods for making and using them |
IL165334A0 (en) | 2004-11-22 | 2006-01-15 | Mediwound Ltd | Debriding composition from bromelain and methods of producing same |
AT502391B1 (de) | 2005-09-20 | 2007-03-15 | Univ Innsbruck Inst Fuer Umwel | Verfahren zur behandlung von ammoniumhaltigem abwasser |
US20110239327A1 (en) * | 2007-01-16 | 2011-09-29 | Rosane Curtis | Nematicidal Effects of Cysteine Proteinases and Methods of Use Thereof to Treat Nematode Infestation |
EP2226382A1 (en) | 2009-03-03 | 2010-09-08 | B.R.A.I.N. Biotechnology Research and Information Network AG | Protease for wound conditioning and skin care |
CA2842291C (en) * | 2011-07-20 | 2020-09-15 | Mediwound Ltd. | Proteolytic extract from bromelain for the treatment of connective tissue disorders |
US10058596B2 (en) | 2011-12-20 | 2018-08-28 | Kci Licensing, Inc. | Composition for enzymatic debridement |
US20150259370A1 (en) * | 2014-03-11 | 2015-09-17 | Ecotech Development LLC | Integrated process extraction of pineapple biomass into fibers and natural products |
AU2016308267A1 (en) * | 2015-08-20 | 2018-03-29 | Anatara Lifesciences Limited | Enzymatic fractions with anti-inflammatory activity |
ES2909565T3 (es) * | 2016-01-31 | 2022-05-09 | Mediwound Ltd | Composición desbridante para el tratamiento de heridas |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3002891A (en) * | 1958-12-12 | 1961-10-03 | Pineapple Res Inst Of Hawaii | Process for the preparation of pineapple stem bromelain |
US2950227A (en) * | 1959-06-05 | 1960-08-23 | Schering Ag | Ferments of the papain type and process of making same |
US4226854A (en) * | 1974-01-08 | 1980-10-07 | Gerold K. V. Klein | Debridement of devitalized tissue with hydrolytic enzyme product |
US4197291A (en) * | 1974-01-08 | 1980-04-08 | Gerold K. V. Klein | Hydrolytic enzyme material |
US4329430A (en) * | 1979-06-04 | 1982-05-11 | Klein Gerold K V | Enzyme mixture |
US4286064A (en) * | 1979-11-05 | 1981-08-25 | Riker Laboratories, Inc. | Process for isolating active debriding agent from bromelain |
US4361551A (en) * | 1979-11-05 | 1982-11-30 | Riker Laboratories, Inc. | Method of enzymatic debridement |
WO1981001242A1 (en) * | 1979-11-05 | 1981-05-14 | Riker Laboratories Inc | Method of enzymatic debridement |
US4645668A (en) * | 1983-08-04 | 1987-02-24 | Biospecifics, Nv | Method for the prevention and treatment of scars with enzymes |
-
1987
- 1987-10-22 GB GB878724728A patent/GB8724728D0/en active Pending
-
1988
- 1988-10-18 IL IL88078A patent/IL88078A/xx not_active IP Right Cessation
- 1988-10-18 AU AU24059/88A patent/AU628790B2/en not_active Ceased
- 1988-10-20 DE DE3888082T patent/DE3888082T2/de not_active Expired - Fee Related
- 1988-10-20 EP EP88309842A patent/EP0313346B1/en not_active Expired - Lifetime
- 1988-10-20 AT AT88309842T patent/ATE102248T1/de not_active IP Right Cessation
- 1988-10-20 ES ES88309842T patent/ES2061682T3/es not_active Expired - Lifetime
- 1988-10-21 CA CA000580989A patent/CA1319121C/en not_active Expired - Fee Related
- 1988-10-21 DK DK589388A patent/DK589388A/da not_active Application Discontinuation
- 1988-10-22 JP JP63267012A patent/JP2644006B2/ja not_active Expired - Fee Related
-
1990
- 1990-11-30 US US07/622,215 patent/US5106621A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0313346B1 (en) | 1994-03-02 |
AU2405988A (en) | 1989-06-08 |
DE3888082T2 (de) | 1994-06-09 |
IL88078A0 (en) | 1989-06-30 |
IL88078A (en) | 1993-08-18 |
DE3888082D1 (de) | 1994-04-07 |
CA1319121C (en) | 1993-06-15 |
JPH0216977A (ja) | 1990-01-19 |
GB8724728D0 (en) | 1987-11-25 |
JP2644006B2 (ja) | 1997-08-25 |
DK589388A (da) | 1989-04-23 |
EP0313346A3 (en) | 1990-05-09 |
DK589388D0 (da) | 1988-10-21 |
US5106621A (en) | 1992-04-21 |
AU628790B2 (en) | 1992-09-24 |
ATE102248T1 (de) | 1994-03-15 |
EP0313346A2 (en) | 1989-04-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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