ES2061406A1 - Nuevos derivados de la 2-(quinolina) con actividad farmacologica. - Google Patents
Nuevos derivados de la 2-(quinolina) con actividad farmacologica.Info
- Publication number
- ES2061406A1 ES2061406A1 ES09300982A ES9300982A ES2061406A1 ES 2061406 A1 ES2061406 A1 ES 2061406A1 ES 09300982 A ES09300982 A ES 09300982A ES 9300982 A ES9300982 A ES 9300982A ES 2061406 A1 ES2061406 A1 ES 2061406A1
- Authority
- ES
- Spain
- Prior art keywords
- quinoline derivatives
- pharmacological activity
- new quinoline
- new
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
NUEVOS DERIVADOS DE LA 2-(QUINOLINA) CON ACTIVIDAD FARMACOLOGICA. NUEVOS DERIVADOS DE LA 2-(QUINOLINA) DE FORMULA I, EN DONDE N ES 0 O 1, Y SUS SALES Y SOLVATOS. LA PRESENTE INVENCION DESCRIBE TAMBIEN PROCEDIMIENTOS PARA SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN. DICHOS COMPUESTOS SON ANTAGONISTAS DUALES DEL PAF Y LA 5-LIPOXIGENASA, Y POR LO TANTO, SON UTILES EN EL TRATAMIENTO Y/O PREVENCION DE LAS ENFERMEDADES DONDE EL PAF Y/O LA 5-LIPOXIGENASA SE HALLAN IMPLICADOS.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09300982A ES2061406B1 (es) | 1993-05-07 | 1993-05-07 | Nuevos derivados de la 2-(quinolina) con actividad farmacologica. |
CA002123057A CA2123057A1 (en) | 1993-05-07 | 1994-05-06 | Quinoline derivatives with pharmacological activity |
EP94107134A EP0624588A1 (en) | 1993-05-07 | 1994-05-06 | New quinoline derivatives with pharmacological activity |
JP6119520A JPH072868A (ja) | 1993-05-07 | 1994-05-09 | 薬理活性を有する新規なキノリン誘導体 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09300982A ES2061406B1 (es) | 1993-05-07 | 1993-05-07 | Nuevos derivados de la 2-(quinolina) con actividad farmacologica. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2061406A1 true ES2061406A1 (es) | 1994-12-01 |
ES2061406B1 ES2061406B1 (es) | 1995-06-01 |
Family
ID=8281737
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09300982A Expired - Fee Related ES2061406B1 (es) | 1993-05-07 | 1993-05-07 | Nuevos derivados de la 2-(quinolina) con actividad farmacologica. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0624588A1 (es) |
JP (1) | JPH072868A (es) |
CA (1) | CA2123057A1 (es) |
ES (1) | ES2061406B1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2294139A1 (en) * | 1997-06-25 | 1998-12-30 | Nikken Chemicals Co., Ltd. | Triazolo-1,4-diazepine compounds and medicinal composition containing the same |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0339416A1 (de) * | 1988-04-29 | 1989-11-02 | Bayer Ag | Gegebenenfalls alpha-substituierte 4-(Chinolin-2-yl-methoxy)phenylessigsäuren und -ester |
EP0367110A1 (en) * | 1988-10-31 | 1990-05-09 | Eisai Co., Ltd. | 1,4-diazepine derivative and its pharmaceutical use |
ES2019840A6 (es) * | 1989-05-13 | 1991-07-01 | Scras | Procedimiento para preparar nuevos derivados de tieno-triazolo-diazepina. |
EP0481891A2 (en) * | 1990-10-16 | 1992-04-22 | Terumo Kabushiki Kaisha | Phenoxyacetic acid compounds, method for production thereof, and pharmaceutical preparations containing same |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4732978A (en) * | 1985-10-03 | 1988-03-22 | American Home Products Corporation | Novel substituted naphthyloxymethyl quinoline derivatives as anti-inflammatory and antiallergy agents |
DE3900261A1 (de) * | 1988-05-31 | 1989-12-07 | Bayer Ag | Substituierte 4-(chinolin-2-yl-methoxy) phenyl-essigsaeure-derivate |
GB8907256D0 (en) * | 1989-03-31 | 1989-05-17 | Rech Et D Applic Scient Scras | New derivatives of hetrazepine as anti-asthmatic anti-allergic and gastro-intestinal protectors |
DE3927369A1 (de) * | 1989-08-19 | 1991-02-21 | Bayer Ag | Substituierte n-(chinolin-2-yl-methoxy)benzyl-sulfonyl-harnstoffe |
JP2971901B2 (ja) * | 1990-03-15 | 1999-11-08 | エーザイ株式会社 | トリアゾロ―1,4―ジアゼピン系化合物 |
DE4105551A1 (de) * | 1991-02-22 | 1992-08-27 | Bayer Ag | 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
DE4107521A1 (de) * | 1991-03-08 | 1992-09-10 | Boehringer Ingelheim Kg | Neue acylaminosubstituierte hetrazepine |
DE4125270A1 (de) * | 1991-07-31 | 1993-02-04 | Bayer Ag | Chinolin-2-yl-methoxybenzylhydroxyharnstoffe |
EP0656004A1 (en) * | 1992-08-20 | 1995-06-07 | Cytomed, Inc. | Dual functional anti-inflammatory and immunosuppressive agents |
-
1993
- 1993-05-07 ES ES09300982A patent/ES2061406B1/es not_active Expired - Fee Related
-
1994
- 1994-05-06 CA CA002123057A patent/CA2123057A1/en not_active Abandoned
- 1994-05-06 EP EP94107134A patent/EP0624588A1/en not_active Withdrawn
- 1994-05-09 JP JP6119520A patent/JPH072868A/ja active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0339416A1 (de) * | 1988-04-29 | 1989-11-02 | Bayer Ag | Gegebenenfalls alpha-substituierte 4-(Chinolin-2-yl-methoxy)phenylessigsäuren und -ester |
EP0367110A1 (en) * | 1988-10-31 | 1990-05-09 | Eisai Co., Ltd. | 1,4-diazepine derivative and its pharmaceutical use |
ES2019840A6 (es) * | 1989-05-13 | 1991-07-01 | Scras | Procedimiento para preparar nuevos derivados de tieno-triazolo-diazepina. |
EP0481891A2 (en) * | 1990-10-16 | 1992-04-22 | Terumo Kabushiki Kaisha | Phenoxyacetic acid compounds, method for production thereof, and pharmaceutical preparations containing same |
Also Published As
Publication number | Publication date |
---|---|
JPH072868A (ja) | 1995-01-06 |
ES2061406B1 (es) | 1995-06-01 |
CA2123057A1 (en) | 1994-11-08 |
EP0624588A1 (en) | 1994-11-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20020304 |