ES2060442T3 - Procedimiento para la preparacion de pentaalquilcromenos sustituidos. - Google Patents
Procedimiento para la preparacion de pentaalquilcromenos sustituidos.Info
- Publication number
- ES2060442T3 ES2060442T3 ES92119637T ES92119637T ES2060442T3 ES 2060442 T3 ES2060442 T3 ES 2060442T3 ES 92119637 T ES92119637 T ES 92119637T ES 92119637 T ES92119637 T ES 92119637T ES 2060442 T3 ES2060442 T3 ES 2060442T3
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- substituted
- pentaalkylchrones
- procedure
- pentaalkylchromenes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
- C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
- C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
- C07C46/08—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring with molecular oxygen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/24—Quinones containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
SE DESCRIBE UN NUEVO PROCEDIMIENTO PARA LA OBTENCION DE PENTAALQUILCROMENOS SUBSTITUIDOS DE LA FORMULA GENERAL. EN EL SE TRANSFORMA UNA TRIALQUILOQUINONA CON UN BUTENOL HALOGENADO, EN UNA TETRAALQUILOHIDROQUINONA, ESTA OXIDA A CONTINUACION EL ATOMO DE HALOGENO, CON UN NUCLEOFILO SUSTITUIDO, Y FINALMENTE SE CICLA EN PRODUCTO FINAL. LOS PENTAALQUILOCROMENOS SON PRODUCTOS INTERMEDIOS ADECUADOS PARA LA OBTENCION DE FARMACOS REDUCTORES DE LIPIDOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH339291 | 1991-11-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2060442T3 true ES2060442T3 (es) | 1994-11-16 |
Family
ID=4254987
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92119637T Expired - Lifetime ES2060442T3 (es) | 1991-11-20 | 1992-11-17 | Procedimiento para la preparacion de pentaalquilcromenos sustituidos. |
Country Status (10)
Country | Link |
---|---|
US (2) | US5364946A (es) |
EP (1) | EP0543346B1 (es) |
JP (1) | JPH0680658A (es) |
KR (1) | KR930010022A (es) |
AT (1) | ATE111095T1 (es) |
CA (1) | CA2082003A1 (es) |
DE (1) | DE59200472D1 (es) |
DK (1) | DK0543346T3 (es) |
ES (1) | ES2060442T3 (es) |
TW (1) | TW213457B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2947503B2 (ja) * | 1994-03-02 | 1999-09-13 | エーザイ株式会社 | アリルキノン誘導体の製造方法および中間体 |
EP0916665A1 (de) * | 1997-11-11 | 1999-05-19 | Lonza A.G. | Verfahren zur Herstellung von Chromanderivaten |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS567737A (en) * | 1979-07-02 | 1981-01-27 | Takeda Chem Ind Ltd | Physiologically active quinone and its preparation |
DE3010505A1 (de) * | 1980-03-19 | 1981-10-01 | Basf Ag, 6700 Ludwigshafen | Chromanderivate, verfahren zu ihrer herstellung, ihre verwendung als stabilisatoren von organischen materialien sowie diese stabilisatoren enthaltende organische materialien |
DE3044109A1 (de) * | 1980-11-24 | 1982-06-24 | Basf Ag, 6700 Ludwigshafen | Chromanderivate sowie verfahren zu deren herstellung |
JPS6051189A (ja) * | 1983-08-30 | 1985-03-22 | Sankyo Co Ltd | チアゾリジン誘導体およびその製造法 |
DK173350B1 (da) * | 1985-02-26 | 2000-08-07 | Sankyo Co | Thiazolidinderivater, deres fremstilling og farmaceutisk paæparat indeholdende dem |
-
1992
- 1992-11-03 CA CA002082003A patent/CA2082003A1/en not_active Abandoned
- 1992-11-16 US US07/977,157 patent/US5364946A/en not_active Expired - Fee Related
- 1992-11-17 ES ES92119637T patent/ES2060442T3/es not_active Expired - Lifetime
- 1992-11-17 AT AT92119637T patent/ATE111095T1/de active
- 1992-11-17 DE DE59200472T patent/DE59200472D1/de not_active Expired - Fee Related
- 1992-11-17 EP EP92119637A patent/EP0543346B1/de not_active Expired - Lifetime
- 1992-11-17 DK DK92119637.4T patent/DK0543346T3/da active
- 1992-11-19 JP JP4310353A patent/JPH0680658A/ja active Pending
- 1992-11-19 KR KR1019920021747A patent/KR930010022A/ko not_active Application Discontinuation
- 1992-12-11 TW TW081109958A patent/TW213457B/zh active
-
1993
- 1993-09-15 US US08/120,789 patent/US5304663A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE111095T1 (de) | 1994-09-15 |
DE59200472D1 (de) | 1994-10-13 |
KR930010022A (ko) | 1993-06-21 |
EP0543346B1 (de) | 1994-09-07 |
US5364946A (en) | 1994-11-15 |
TW213457B (es) | 1993-09-21 |
EP0543346A1 (de) | 1993-05-26 |
US5304663A (en) | 1994-04-19 |
JPH0680658A (ja) | 1994-03-22 |
CA2082003A1 (en) | 1993-05-21 |
DK0543346T3 (da) | 1994-10-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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