ES2059683T3 - Composiciones farmaceuticas microencapsuladas con separacion de fases, perfeccionadas, utiles para aliviar enfermedades dentales. - Google Patents

Composiciones farmaceuticas microencapsuladas con separacion de fases, perfeccionadas, utiles para aliviar enfermedades dentales.

Info

Publication number
ES2059683T3
ES2059683T3 ES89121887T ES89121887T ES2059683T3 ES 2059683 T3 ES2059683 T3 ES 2059683T3 ES 89121887 T ES89121887 T ES 89121887T ES 89121887 T ES89121887 T ES 89121887T ES 2059683 T3 ES2059683 T3 ES 2059683T3
Authority
ES
Spain
Prior art keywords
severe
perfected
relief
useful
dental diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89121887T
Other languages
English (en)
Inventor
James Ronald Lawter
Michael Gerard Lanzilotti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2059683T3 publication Critical patent/ES2059683T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

COMPOSICIONES ORALES PARA LA ADMINISTRACION LOCAL DE UN AGENTE TERAPEUTICO A UNA BOLSA PERIODONTAL DE UN PACIENTE PARA ALIVIAR ENFERMEDADES DENTALES COMPRENDE UNA PLURALIDAD DE MICROPARTICULAS DISTINTAS, SECAS CADA UNA DE LAS CUALES COMPRENDE UNA CANTIDAD EFECTIVA DE AL MENOS UN AGENTE TERAPEUTICO DISPERSADO EN UNA MATRIZ QUE COMPRENDE UN POLIMERO BIOCOMPATIBLE Y BIODEGRADABLE DE PREFERIBLEMENTE, LAS MICROPARTICULAS SECAS Y DISPERSADAS DENTRO DE LA BOLSA PERIODONTAL POR EL QUE EN CONTACTO CON EL ENTORNO HUMEDO DE LA BOLSA, SE HIDRATA, SE CONVIERTE PEGAJOSO Y SE ADHIERE A OTRO Y AL TEJIDO QUE RODEA LA BOLSA PARA MANTENER EL CONTACTO INTIMO CON EL TEJIDO EN CUESTION PARA INDUCIR BENEFICIOS TERAPEUTICOS LARGO TIEMPO
ES89121887T 1988-12-22 1989-11-27 Composiciones farmaceuticas microencapsuladas con separacion de fases, perfeccionadas, utiles para aliviar enfermedades dentales. Expired - Lifetime ES2059683T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28873988A 1988-12-22 1988-12-22

Publications (1)

Publication Number Publication Date
ES2059683T3 true ES2059683T3 (es) 1994-11-16

Family

ID=23108436

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89121887T Expired - Lifetime ES2059683T3 (es) 1988-12-22 1989-11-27 Composiciones farmaceuticas microencapsuladas con separacion de fases, perfeccionadas, utiles para aliviar enfermedades dentales.

Country Status (15)

Country Link
EP (1) EP0374532B1 (es)
JP (1) JP2901673B2 (es)
AR (1) AR243768A1 (es)
AT (1) ATE111729T1 (es)
AU (1) AU635913B2 (es)
CA (1) CA2006106C (es)
DE (1) DE68918419T2 (es)
DK (1) DK175150B1 (es)
ES (1) ES2059683T3 (es)
HK (1) HK1000314A1 (es)
IE (1) IE65813B1 (es)
IL (1) IL92699A (es)
NZ (1) NZ231792A (es)
PT (1) PT92618B (es)
ZA (1) ZA899863B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0374531B1 (en) * 1988-12-22 1994-05-04 American Cyanamid Company Method for the treatment of periodontal disease by sustained delivery of a therapeutic agent to the periodontal pocket, composition of matter therefor and apparatus for the administration thereof
EP3242318A1 (en) * 2003-12-19 2017-11-08 The University of North Carolina at Chapel Hill Monodisperse micro-structure or nano-structure product
US8865198B2 (en) 2010-10-25 2014-10-21 Dexcel Pharma Technologies Ltd. Method for treating a periodontal disease
JP6376850B2 (ja) * 2014-06-06 2018-08-22 株式会社ファンケル 表面処理剤
WO2017039435A1 (en) * 2015-08-28 2017-03-09 Rijksuniversiteit Groningen Means and methods for sustained oxygen release in situ

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4685883A (en) * 1983-09-12 1987-08-11 Jernberg Gary R Local delivery of chemotherapeutic agents for the treatment of periodontal disease
US4701320A (en) * 1984-11-29 1987-10-20 Lederle (Japan), Ltd. Composition stably containing minocycline for treating periodontal diseases
JPS62223112A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
US4780320A (en) * 1986-04-29 1988-10-25 Pharmetrix Corp. Controlled release drug delivery system for the periodontal pocket
US5000886A (en) * 1987-05-26 1991-03-19 American Cyanamid Company Silicone-hardened pharmaceutical microcapsules and process of making the same
EP0374531B1 (en) * 1988-12-22 1994-05-04 American Cyanamid Company Method for the treatment of periodontal disease by sustained delivery of a therapeutic agent to the periodontal pocket, composition of matter therefor and apparatus for the administration thereof

Also Published As

Publication number Publication date
IE894146L (en) 1990-06-22
ZA899863B (en) 1990-10-31
JP2901673B2 (ja) 1999-06-07
IE65813B1 (en) 1995-11-15
DK655989A (da) 1990-06-23
PT92618A (pt) 1990-06-29
DE68918419D1 (de) 1994-10-27
ATE111729T1 (de) 1994-10-15
DK175150B1 (da) 2004-06-14
AU635913B2 (en) 1993-04-08
PT92618B (pt) 1995-09-12
EP0374532B1 (en) 1994-09-21
CA2006106C (en) 1999-10-26
CA2006106A1 (en) 1990-06-22
DE68918419T2 (de) 1995-05-04
HK1000314A1 (en) 1998-02-27
NZ231792A (en) 1992-04-28
IL92699A (en) 1994-08-26
JPH02212418A (ja) 1990-08-23
IL92699A0 (en) 1990-09-17
AR243768A1 (es) 1993-09-30
AU4707889A (en) 1990-06-28
EP0374532A2 (en) 1990-06-27
DK655989D0 (da) 1989-12-21
EP0374532A3 (en) 1991-08-07

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