ES2056046T3 - Dipeptidos y procedimiento. - Google Patents
Dipeptidos y procedimiento.Info
- Publication number
- ES2056046T3 ES2056046T3 ES86308176T ES86308176T ES2056046T3 ES 2056046 T3 ES2056046 T3 ES 2056046T3 ES 86308176 T ES86308176 T ES 86308176T ES 86308176 T ES86308176 T ES 86308176T ES 2056046 T3 ES2056046 T3 ES 2056046T3
- Authority
- ES
- Spain
- Prior art keywords
- het
- substd
- opt
- dipeptides
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
- C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
LA HIDROXI-ASPARTAMA Y SUS DERIVADOS SE OBTIENEN POR ACOPLAMIENTO ENZIMATICO DE FENILSERINA O UN DERIVADO SUYO CON ACIDO ASPARTICO O UN DERIVADO SUYO. LA INVENCION TAMBIEN PROPORCIONA NUEVOS ESTERES DE FENILSERINA QUE PUEDEN OBTENERSE (1) A PARTIR DE BENZALDEHIDO Y UN ESTER DE GLICINA EMPLEANDO HIDROXIMETILTRANSFERASA DE SERINA O (2) A PARTIR DE ACETATO DE METIL BENZOILO. LA HIDROXI-ASPARTAMA Y SUS DERIVADOS PUEDE SER HIDROGENADA PARA PRODUCIR ASPARTAMA O UN DERIVADO SUYO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78959385A | 1985-10-21 | 1985-10-21 | |
US06/789,595 US4710583A (en) | 1985-10-21 | 1985-10-21 | Dipeptides and process |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2056046T3 true ES2056046T3 (es) | 1994-10-01 |
Family
ID=27120931
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93110704T Expired - Lifetime ES2090789T3 (es) | 1985-10-21 | 1986-10-21 | Analogos dipeptidos de aspertamo y procedimiento para su preparacion asi como una nueva preparacion de aspertamo. |
ES86308176T Expired - Lifetime ES2056046T3 (es) | 1985-10-21 | 1986-10-21 | Dipeptidos y procedimiento. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93110704T Expired - Lifetime ES2090789T3 (es) | 1985-10-21 | 1986-10-21 | Analogos dipeptidos de aspertamo y procedimiento para su preparacion asi como una nueva preparacion de aspertamo. |
Country Status (5)
Country | Link |
---|---|
EP (2) | EP0574028B1 (es) |
AT (1) | ATE141927T1 (es) |
DE (2) | DE3689817T2 (es) |
ES (2) | ES2090789T3 (es) |
NZ (1) | NZ217813A (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5102792A (en) * | 1987-08-13 | 1992-04-07 | W. R. Grace & Co.-Conn. | Selective production of L-serine derivative isomers |
DE3738908A1 (de) * | 1987-11-17 | 1989-05-24 | Hoechst Ag | Verfahren zur enzymatischen peptidsynthese mit mindestens einer nicht-proteinogenen aminosaeure sowie die neuen, bei der synthese anfallenden peptide |
DK163435C (da) * | 1988-08-12 | 1992-07-20 | Carlsberg Biotechnology Ltd | Fremgangsmaade til enzymatisk fremstilling af dipeptider og derivater deraf |
IL109729A0 (en) * | 1993-05-25 | 1994-08-26 | Lilly Co Eli | Process for preparing serine hydroxymethyl-transferase |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3475403A (en) * | 1967-01-20 | 1969-10-28 | Searle & Co | Aspartic acid containing dipeptide lower alkyl esters |
JPS543952B2 (es) | 1973-03-22 | 1979-02-28 | ||
US4086136A (en) * | 1975-10-23 | 1978-04-25 | (Zaidanhojin) Sagami Chemical Research Center | Process for producing a peptide using a serine or thiol proteinase |
JPS55135595A (en) * | 1979-04-03 | 1980-10-22 | Toyo Soda Mfg Co Ltd | Preparation of dipeptide |
ATE9995T1 (de) * | 1981-07-10 | 1984-11-15 | Pfizer Inc. | Verzweigte amide von l-aspartyl-daminos[uredipeptiden und deren verbindungen. |
HU187215B (en) | 1983-01-26 | 1985-11-28 | Egyt Gyogyszervegyeszeti Gyar | Method for producing pharmaceutical product of high actor content and prolonged effect |
HU190864B (en) * | 1983-12-08 | 1986-11-28 | Alkaloida Vegyeszeti Gyar | Process for production of phenil-alanin derivatives |
IT1175926B (it) * | 1984-01-13 | 1987-08-12 | Debi Derivati Biologici | Procedimento per la preparazione dell'estere metilico di alfa-l-aspartil-l-fenilalanina |
-
1986
- 1986-10-06 NZ NZ217813A patent/NZ217813A/xx unknown
- 1986-10-21 ES ES93110704T patent/ES2090789T3/es not_active Expired - Lifetime
- 1986-10-21 EP EP93110704A patent/EP0574028B1/en not_active Expired - Lifetime
- 1986-10-21 DE DE3689817T patent/DE3689817T2/de not_active Expired - Fee Related
- 1986-10-21 ES ES86308176T patent/ES2056046T3/es not_active Expired - Lifetime
- 1986-10-21 AT AT93110704T patent/ATE141927T1/de not_active IP Right Cessation
- 1986-10-21 DE DE3650564T patent/DE3650564T2/de not_active Expired - Fee Related
- 1986-10-21 EP EP86308176A patent/EP0220923B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU6429486A (en) | 1987-04-30 |
EP0574028B1 (en) | 1996-08-28 |
DE3650564D1 (de) | 1996-10-02 |
DE3689817T2 (de) | 1994-12-08 |
NZ217813A (en) | 1991-01-29 |
DE3689817D1 (de) | 1994-06-01 |
AU607123B2 (en) | 1991-02-28 |
ES2090789T3 (es) | 1996-10-16 |
ATE141927T1 (de) | 1996-09-15 |
EP0220923A2 (en) | 1987-05-06 |
EP0220923B1 (en) | 1994-04-27 |
EP0574028A1 (en) | 1993-12-15 |
DE3650564T2 (de) | 1997-01-16 |
EP0220923A3 (en) | 1989-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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