ES2055542T3 - N-fenil-n'-alquilsulfonilureas, procedimiento para su preparacion y composiciones antitumor que las contienen. - Google Patents
N-fenil-n'-alquilsulfonilureas, procedimiento para su preparacion y composiciones antitumor que las contienen.Info
- Publication number
- ES2055542T3 ES2055542T3 ES91306391T ES91306391T ES2055542T3 ES 2055542 T3 ES2055542 T3 ES 2055542T3 ES 91306391 T ES91306391 T ES 91306391T ES 91306391 T ES91306391 T ES 91306391T ES 2055542 T3 ES2055542 T3 ES 2055542T3
- Authority
- ES
- Spain
- Prior art keywords
- alquilsulfonilureas
- fenil
- procedure
- contain
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/55—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/56—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/67—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfonamide groups, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN COMPUESTO DE FORMULA: DONDE X ELEVADO 1 ES HALO; X (AL CUADRADO) ES HIDROGENO, HALO O CF SUB 3; A ES ALQUILO C SUB 2 C SUB 8; ALQUILO C SUB 1 C SUB 2 FENILO O ALQILO C SUB 1 UB N, DONDE N ES 1-3, Y Z ES OXIGENO O AZUFRE: Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, PARA LA FABRICACION DE MEDICAMENTOS PARA EL TRATAMIENTO DE NOPLASMAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/554,218 US5216026A (en) | 1990-07-17 | 1990-07-17 | Antitumor compositions and methods of treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2055542T3 true ES2055542T3 (es) | 1994-08-16 |
Family
ID=24212508
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91306391T Expired - Lifetime ES2055542T3 (es) | 1990-07-17 | 1991-07-15 | N-fenil-n'-alquilsulfonilureas, procedimiento para su preparacion y composiciones antitumor que las contienen. |
Country Status (8)
Country | Link |
---|---|
US (2) | US5216026A (es) |
EP (1) | EP0467621B1 (es) |
JP (1) | JPH04234353A (es) |
AT (1) | ATE107275T1 (es) |
CA (1) | CA2047138A1 (es) |
DE (1) | DE69102503T2 (es) |
DK (1) | DK0467621T3 (es) |
ES (1) | ES2055542T3 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5254589A (en) * | 1991-10-15 | 1993-10-19 | Warner-Lambert Company | Sulfonyl urea and carbamate ACAT inhibitors |
JP3196404B2 (ja) * | 1993-03-16 | 2001-08-06 | 王子製紙株式会社 | 感熱記録体 |
US6969303B1 (en) * | 1994-10-12 | 2005-11-29 | Nextec, Inc. | Method and composition for removing coatings which contain hazardous elements |
EP0929540A4 (en) * | 1996-10-04 | 2001-12-12 | Lilly Co Eli | ANTI-TUMOR COMPOSITIONS AND THERAPEUTIC METHODS |
WO1998014185A1 (en) * | 1996-10-04 | 1998-04-09 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
US6174921B1 (en) | 1997-10-02 | 2001-01-16 | Eli Lilly And Company | Antitumor compositions and methods of treatment |
ITMI20010395A1 (it) * | 2001-02-27 | 2002-08-27 | Dompe Spa | Omega-amminoalchilammidi di acidi r-2-aril-propionici come inibitori della chemiotassi di cellule polimorfonucleate e mononucleate |
EP1457485A1 (en) * | 2003-03-14 | 2004-09-15 | Dompé S.P.A. | Sulfonic acids, their derivatives and pharmaceutical compositions containing them |
US8298373B2 (en) | 2008-02-07 | 2012-10-30 | University Of New Brunswick | Combined process of peroxide bleaching of wood pulps and addition of optical brightening agents |
AU2018210525B2 (en) | 2017-01-23 | 2022-06-02 | Genentech, Inc. | Chemical compounds as inhibitors of interleukin-1 activity |
AU2018317800A1 (en) | 2017-08-15 | 2020-02-13 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
WO2019043610A1 (en) * | 2017-08-31 | 2019-03-07 | Cadila Healthcare Limited | NEW SUBSTITUTED SULFONYLUREA DERIVATIVES |
EP3823726A1 (en) | 2018-07-20 | 2021-05-26 | F. Hoffmann-La Roche SA | Sulfonylurea compounds as inhibitors of interleukin-1 activity |
US12084416B2 (en) * | 2019-01-14 | 2024-09-10 | Zydus Lifesciences Limited | Substituted sulfonylurea derivatives |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA601648A (en) * | 1960-07-12 | Korger Gerhard | Sulphonyl-ureas and a process for their manufacture | |
US3083207A (en) * | 1963-03-26 | Indolinesulfonylureas | ||
DE1144259B (de) * | 1956-05-29 | 1963-02-28 | Hoechst Ag | Verfahren zur Herstellung von Sulfonylharnstoffen |
DE1174306B (de) * | 1956-05-23 | 1964-07-23 | Hoechst Ag | Verfahren zur Herstellung von Sulfonylharnstoffen |
US3097241A (en) * | 1956-08-10 | 1963-07-09 | Hoechst Ag | Nu-cyclohexane-sulphonyl-n'-(beta-phenylethyl)-urea |
US2990326A (en) * | 1957-07-09 | 1961-06-27 | Hoechst Ag | Sulfonyl-urethanes and a process for preparing them |
US2979437A (en) * | 1958-09-02 | 1961-04-11 | Pfizer & Co C | Substituted styryl, and thienylethenyl, pyridylethenyl sulfonylureas and method of treating diabetes |
NL218580A (es) * | 1960-04-28 | |||
US3097242A (en) * | 1960-06-29 | 1963-07-09 | Olin Mathieson | Hydrindene sulfonylureas |
DE1159937B (de) * | 1960-06-29 | 1963-12-27 | Heyden Chem Fab | Verfahren zur Herstellung von Hydrindensulfonylharnstoffen |
US3102121A (en) * | 1961-06-29 | 1963-08-27 | Olin Mathieson | Novel cumaransulfonylureas and 2,3-dihydrothionaphthenesulfonylureas |
DE1240866B (de) * | 1961-06-29 | 1967-05-24 | Heyden Chem Fab | Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen |
US3155721A (en) * | 1961-11-30 | 1964-11-03 | Lilly Co Eli | Novel sulfonylureas |
BE634577A (es) * | 1962-04-11 | |||
US3849110A (en) * | 1963-01-07 | 1974-11-19 | Lilly Co Eli | Herbicidal method employing aryl-sulfonylureas or salts thereof |
CH435243A (de) * | 1964-03-26 | 1967-05-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen N'-substituierten N-Arylsulfonyl-harnstoffen |
BE791449A (fr) * | 1971-11-17 | 1973-05-16 | Roussel Uclaf | Nouvelles urees substituees et procede de |
AR208187A1 (es) * | 1973-12-05 | 1976-12-09 | Pfizer | Metodo para la preparacion derivados de n-carbamoil-2-feniletensulfonamida |
US3983107A (en) * | 1973-12-05 | 1976-09-28 | Pfizer Inc. | Hypolipidemic alkenesulfonamides |
US4276290A (en) * | 1977-10-10 | 1981-06-30 | Rohm And Haas Company | Phosphonoureide and phosphonothioureide anthelmintics |
US4365990A (en) * | 1979-09-21 | 1982-12-28 | Stauffer Chemical Company | Sulfonylurea herbicidal antidotes |
AU1862083A (en) * | 1982-09-02 | 1984-03-08 | Duphar International Research B.V. | Tumor growth inhibitors |
IT1161220B (it) * | 1983-04-21 | 1987-03-18 | Montedison Spa | Diidro-benzofurano derivati ad attivita' erbicida |
DE3330603A1 (de) * | 1983-08-25 | 1985-03-21 | Hoechst Ag, 6230 Frankfurt | Neue 2-amino-alkenylsulfonylharnstoffe |
CA1208561A (en) * | 1984-01-19 | 1986-07-29 | Marius S. Brouwer | Pharmaceutical compositions containing benzoylurea compounds |
US4845128A (en) * | 1984-06-27 | 1989-07-04 | Eli Lilly And Company | N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides |
GR862353B (en) * | 1985-09-23 | 1987-01-19 | Lilly Co Eli | Anti-tumor method and compounds |
CA1331464C (en) * | 1987-05-12 | 1994-08-16 | Eli Lilly And Company | Anti-tumor method and compounds |
-
1990
- 1990-07-17 US US07/554,218 patent/US5216026A/en not_active Expired - Fee Related
-
1991
- 1991-07-15 DK DK91306391.3T patent/DK0467621T3/da active
- 1991-07-15 EP EP91306391A patent/EP0467621B1/en not_active Expired - Lifetime
- 1991-07-15 AT AT91306391T patent/ATE107275T1/de active
- 1991-07-15 ES ES91306391T patent/ES2055542T3/es not_active Expired - Lifetime
- 1991-07-15 DE DE69102503T patent/DE69102503T2/de not_active Expired - Fee Related
- 1991-07-16 JP JP3175062A patent/JPH04234353A/ja active Pending
- 1991-07-16 CA CA002047138A patent/CA2047138A1/en not_active Abandoned
-
1993
- 1993-03-24 US US08/036,640 patent/US6147115A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69102503T2 (de) | 1994-11-24 |
US6147115A (en) | 2000-11-14 |
DE69102503D1 (de) | 1994-07-21 |
DK0467621T3 (da) | 1994-07-11 |
US5216026A (en) | 1993-06-01 |
EP0467621A1 (en) | 1992-01-22 |
CA2047138A1 (en) | 1992-01-18 |
EP0467621B1 (en) | 1994-06-15 |
ATE107275T1 (de) | 1994-07-15 |
JPH04234353A (ja) | 1992-08-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2055542T3 (es) | N-fenil-n'-alquilsulfonilureas, procedimiento para su preparacion y composiciones antitumor que las contienen. | |
DK0565549T3 (da) | Anvendelse af 1,3-oxathiolannucleosidanaloger til fremstilling af et præparat til behandling af hepatitis B | |
TW229156B (es) | ||
ZA9710292B (en) | Atherosclerosis treatment | |
PT95852A (pt) | Processo para a preparacao de agentes hipoglicemicos de oxazolidinediona | |
DE69305276D1 (de) | Arylglycinamidderivate, Verfahren zur deren Herstellung und deren Verwendung zur Therapie der Dysurie | |
DK148844C (da) | Analogifremgangsmaade til fremstilling af dihydroxyalkylsubstituerede xanthinderivater | |
ES523658A0 (es) | Procedimiento para la obtencion de azolil-cetonas y -alcoholes sustituidos. | |
GR79245B (es) | ||
DE69105572D1 (de) | 4-Phenylphthalazin-Derivate. | |
DE3879258D1 (de) | Praeparat gegen ulcus. | |
DK0617959T3 (da) | Lægemiddel til behandling af hudsygdomme | |
ES2124379T3 (es) | Nuevos benzo-espiro-alquenos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
ES8607265A1 (es) | Un procedimiento para la preparacion de nuevos derivados de aminoalcoholes | |
BR8707184A (pt) | Processo para preparacao de composto | |
DK0469782T3 (da) | Behandling af katarakt med prostacyclinforbindelser | |
ES2168119T3 (es) | Derivados de quinoxalina para el tratamiento de tinnitus. | |
GB8801289D0 (en) | Oxadiazole compounds their preparation & their use as pesticides | |
DK0635011T3 (da) | Hydrazid-derivater af 3,4-dihydro-2H-1-benzopyraner | |
BR8600203A (pt) | Processo para a preparacao de furazanos substituidos,composicoes praguicidas,processos para combater pragas e para a preparacao de composicoes | |
ES2101269T3 (es) | Nuevos derivados de 1-fenil-biciclo-(2.2.2)-octano, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
HUT58471A (en) | Herbicidal composition comprising (sulfamidosulfonyl)-urea derivatives as active ingredient and process for producing the active ingredients | |
DE3470882D1 (en) | N-substituted tetrahydrothiazines, process for their preparation, and their use as pesticides | |
FI941850A0 (fi) | Uusi yhdiste, joka on leustroduksiini H, sen valmistus ja terapeuttinen käyttö |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 467621 Country of ref document: ES |