ES2055172T3 - Procedimiento y reactivo para determinar sustancias detectables inmunologicamente. - Google Patents

Procedimiento y reactivo para determinar sustancias detectables inmunologicamente.

Info

Publication number
ES2055172T3
ES2055172T3 ES90101095T ES90101095T ES2055172T3 ES 2055172 T3 ES2055172 T3 ES 2055172T3 ES 90101095 T ES90101095 T ES 90101095T ES 90101095 T ES90101095 T ES 90101095T ES 2055172 T3 ES2055172 T3 ES 2055172T3
Authority
ES
Spain
Prior art keywords
solid phase
bound
binding
detectable substances
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90101095T
Other languages
English (en)
Inventor
Hubert Dr Rer Nat Bayer
Peter Dr Rer Nat Kirch
Erhard Dr Rer Nat Kopetzki
Christian Dr Rer Nat Klein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3901638A external-priority patent/DE3901638C2/de
Priority claimed from DE19893924239 external-priority patent/DE3924239A1/de
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2055172T3 publication Critical patent/ES2055172T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

PARA DETERMINAR SUSTANCIAS INMUNOLOGICAS DEMOSTRABLES SEGUN EL PRINCIPIO DEL HETEROGENEO IMNUNOASSAYS MEDIANTE INCUBACION Y POR LO MENOS DOS RECEPTORES R1 Y R2 DE LOS QUE R1 TRANSMITE LA UNION A LA FASE SOLIDA Y R2 ES UN CONJUGADO DE LIGADOS CON UNA DETERMINADA SUSTANCIA Y UNA MARCACION, UTILIZANDO UNA FASE SOLIDA QUE ESTE LIGADA A UN COMPONENTE DE REACCION ESPECIFICAMENTE FRAGUABLE, SEPARACION DE LA FASE SOLIDA DE LA LIQUIDA Y DETERMINACION DE LA MARCACION EUN UNA DE AMBAS FASES, SE UTILIZA COMO FASE SOLIDA UN MATERIAL A CUYA SUPERFICIE ESTEN UNIDOS ASOCIADOS ESPECIFICAMENTE UNIBLES Y QUE ENCUBRAN LA SOLUCION DE LA PRUEBA CON VARIOS RECEPTORES DIFERENTES R1, PARA LO QUE CADA RECEPTOR R1 TIENE TANTO ZONAS DE UNION PARA LOS ASOCIADOS DE LA FASE SOLIDA ESPECIFICAMENTE UNIBLES COMO TAMBIEN ZONAS DE UNION PARA UNA SUSTANCIA A DETERMINAR.
ES90101095T 1989-01-20 1990-01-19 Procedimiento y reactivo para determinar sustancias detectables inmunologicamente. Expired - Lifetime ES2055172T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3901638A DE3901638C2 (de) 1988-05-25 1989-01-20 Verfahren zur Bestimmung einer immunologisch nachweisbaren Substanz und dazu geeignetes Reaktionsgefäß
DE19893924239 DE3924239A1 (de) 1989-07-21 1989-07-21 Verfahren zur bestimmung von immunologisch nachweisbaren substanzen

Publications (1)

Publication Number Publication Date
ES2055172T3 true ES2055172T3 (es) 1994-08-16

Family

ID=25876968

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90101095T Expired - Lifetime ES2055172T3 (es) 1989-01-20 1990-01-19 Procedimiento y reactivo para determinar sustancias detectables inmunologicamente.

Country Status (8)

Country Link
EP (1) EP0379216B1 (es)
JP (1) JPH0827284B2 (es)
AT (1) ATE107030T1 (es)
AU (1) AU633041B2 (es)
CA (1) CA2008100A1 (es)
DE (1) DE59005973D1 (es)
DK (1) DK0379216T3 (es)
ES (1) ES2055172T3 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4211108A1 (de) * 1992-04-03 1993-10-07 Boehringer Mannheim Gmbh Viruslösung zum Einsatz bei Immunoassays
DE4218257A1 (de) * 1992-06-03 1993-12-09 Behringwerke Ag Verfahren zur immunchemischen Bestimmung eines Analyten
WO1994003807A1 (en) * 1992-08-03 1994-02-17 Gec-Marconi Limited Separation method
GB2271634B (en) * 1992-09-18 1997-04-09 Marconi Gec Ltd Separation method
DE4236189A1 (de) * 1992-10-27 1994-04-28 Boehringer Mannheim Gmbh Verfahren zur simultanen Bestimmung von Antigenen und Antikörpern
GB2273157A (en) * 1992-11-27 1994-06-08 Marconi Gec Ltd Immunological detection/separation using a plurality of immobilised binding agents
CZ315094A3 (en) * 1993-04-14 1996-01-17 Int Murex Tech Corp Immunoassay
GB2282884A (en) * 1993-04-14 1995-04-19 Int Murex Tech Corp Immunoassay
US6383740B2 (en) 1999-07-30 2002-05-07 Bioergonomics, Inc. Methods for simultaneously detecting both members of a binding pair
JP5500423B2 (ja) * 2009-12-24 2014-05-21 東洋紡株式会社 アレルギー検査方法
CN116879550A (zh) * 2019-12-31 2023-10-13 科美博阳诊断技术(上海)有限公司 一种人类免疫缺陷病毒抗体检测试剂盒及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5510590A (en) * 1978-05-04 1980-01-25 Wellcome Found Enzyme immunity quantity analysis
IL55816A (en) * 1978-10-30 1982-04-30 Ames Yissum Ltd Method for simultaneous immunoassay of several different antibodies and a kit therefor
US4378344A (en) * 1979-09-28 1983-03-29 Ventrex Laboratories, Inc. Method and apparatus for performing multiple, simultaneous in vitro diagnostic tests using a solid phase system
ZA855031B (en) * 1984-08-31 1986-02-26 New York Blood Center Inc Assay for simultaneous detection of antigen and antibody in given serum
GB2181840B (en) * 1985-10-16 1989-11-29 Farmos Group Ltd Method for the immunoassay of a macromolecular analyte
US4772550A (en) * 1986-02-10 1988-09-20 Miles Inc. Heterogeneous specific binding assay employing an aggregatable binding reagent
US4778751A (en) * 1986-05-12 1988-10-18 Diagnostic Products Corporation Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies
FR2601455B1 (fr) * 1986-07-11 1989-08-04 Stallergenes Lab Nouveaux reactifs biologiques en phase solide et leur procede d'obtention
DE3705686C2 (de) * 1987-02-23 1995-11-30 Boehringer Mannheim Gmbh Verfahren zur Bestimmung von Antikörpern

Also Published As

Publication number Publication date
JPH0827284B2 (ja) 1996-03-21
JPH02228561A (ja) 1990-09-11
EP0379216A1 (de) 1990-07-25
CA2008100A1 (en) 1990-07-20
DE59005973D1 (de) 1994-07-14
ATE107030T1 (de) 1994-06-15
AU633041B2 (en) 1993-01-21
AU4858290A (en) 1990-07-26
EP0379216B1 (de) 1994-06-08
DK0379216T3 (da) 1994-10-31

Similar Documents

Publication Publication Date Title
ATE221997T1 (de) Immunoassays zum nachweis von antiphospholipid- antikörpern
ES2068844T3 (es) Dispositivo analitico en fase solida y metodo para su utilizacion.
KR890012165A (ko) 이온-포획 분석방법 및 장치
ES2055172T3 (es) Procedimiento y reactivo para determinar sustancias detectables inmunologicamente.
ATE113723T1 (de) Verfahren zur bestimmung von antikörpern.
KR970074793A (ko) 올리고머화된 수용체를 사용한 결정 방법
CA2007532A1 (en) Threshold ligand-receptor assay
ES2123578T3 (es) Elemento de analisis para inmunoensayos.
DE59409947D1 (de) Verringerung des Hook-Effekts in Immuntests mit teilchenförmigem Trägermaterial
KR900003632A (ko) 특이적으로 결합가능한 물질의 정량방법
DK0378175T3 (da) Diagnostisk påvisning under anvendelse af kimære antistoffer
KR900002075A (ko) 특이적으로 결합가능한 물질의 정량 방법 및 시약
ES2023868B3 (es) Procedimiento de determinacion inmunometrico
ES2061881T3 (es) Procedimiento para la determinacion de anticuerpos especificos de la clase de un antigeno asi como un reactivo apropiado para ello.
DE68909479D1 (de) Immunoassay mit phasentrennschritt und geraet dafuer.
FR2582103B1 (fr) Procede de determination d'une substance biologique dans un echantillon
EP0274198A3 (en) Immuno assays
ES2097851T3 (es) Procedimiento para la determinacion de una sustancia capaz de fijarse inmunologicamente.
ES2036189T3 (es) Un metodo para efectuar un inmunoensayo de diagnostico.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 379216

Country of ref document: ES