ES2053677T3 - Procedimiento para la obtencion de un biocatalizador y su empleo para la disociacion de racematos. - Google Patents

Procedimiento para la obtencion de un biocatalizador y su empleo para la disociacion de racematos.

Info

Publication number
ES2053677T3
ES2053677T3 ES88117889T ES88117889T ES2053677T3 ES 2053677 T3 ES2053677 T3 ES 2053677T3 ES 88117889 T ES88117889 T ES 88117889T ES 88117889 T ES88117889 T ES 88117889T ES 2053677 T3 ES2053677 T3 ES 2053677T3
Authority
ES
Spain
Prior art keywords
biocatalizer
racematos
employment
dissociation
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88117889T
Other languages
English (en)
Inventor
Dieter Dr Urban
Wolfgang Dr Ladner
Axel Dr Paul
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2053677T3 publication Critical patent/ES2053677T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)

Abstract

PROCESO PARA LA PRODUCCION DE UN BIOCATALIZADOR MEDIANTE MEZCLA DE: A) UN COPOLIMERIZADO NO SOLUBLE, SOLO UN POCO ESPONJABLE, DE UNA N - VINILACTAMA CON UNA AMIDA DE ACIDO CICLICA QUE CONTENGA AL MENOS 2 GRUPOS ETILENICOS NO SATURADOS COPOLIMERIZABLES, DE LOS QUE AL MENOS UNO ESTE ENLAZADO DIRECTAMENTE A NITROGENO - AMIDA, B) PANCREALIPASA PORCINA CRUDA, C) AL MENOS UN ALCOHOL HIDROSOLUBLE BI - HASTA HEXAVALENTE CON DE DOS A SEIS ATOMOS DE CARBONO Y D) UNA SOLUCION TAMPON ACUOSA CON UN PH DE 5 A 9, A UNA TEMPERATURA ENTRE 0 Y 40 (GRADOS) C, FILTRANDO LA MEZCLA TRAS UN TIEMPO DE 1 MINUTO A 3 DIAS Y LAVANDO LA TORTA DE FILTRACION. LA PATENTE AFECTA TAMBIEN AL BIOCATALIZADOR MISMO ASI COMO A SU UTILIZACION PARA LA SEPARACION DE RAZEMAT DE ESTERES DE ALCOHOLES RAZEMICOS.
ES88117889T 1987-11-04 1988-10-27 Procedimiento para la obtencion de un biocatalizador y su empleo para la disociacion de racematos. Expired - Lifetime ES2053677T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873737335 DE3737335A1 (de) 1987-11-04 1987-11-04 Verfahren zur herstellung eines biokatalysators und dessen verwendung zur razematspaltung

Publications (1)

Publication Number Publication Date
ES2053677T3 true ES2053677T3 (es) 1994-08-01

Family

ID=6339709

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88117889T Expired - Lifetime ES2053677T3 (es) 1987-11-04 1988-10-27 Procedimiento para la obtencion de un biocatalizador y su empleo para la disociacion de racematos.

Country Status (6)

Country Link
US (1) US5021345A (es)
EP (1) EP0315831B1 (es)
JP (1) JPH01148187A (es)
DE (2) DE3737335A1 (es)
DK (1) DK613088A (es)
ES (1) ES2053677T3 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
US5258516A (en) * 1990-12-20 1993-11-02 Nc State University Optically pure D,E ring intermediates useful for the synthesis of camptothecin and camptothecin analogs
US5212317A (en) * 1990-12-20 1993-05-18 North Carolina State University Methods and intermediates for the assymmetric synthesis of camptothecin and camptothecin analogs
US5264579A (en) * 1990-12-20 1993-11-23 North Carolina State University D ring intermediates for the synthesis of camptothecin and camptothecin analogs
US5315007A (en) * 1990-12-20 1994-05-24 North Carolina State University Process for making DE ring intermediates for the synthesis of camptothecin and camptothecin analogs
US5262571A (en) * 1992-03-20 1993-11-16 North Carolina State University Cycloalkyl-based chiral auxiliaries and method making the same
JPH06335398A (ja) * 1993-05-31 1994-12-06 Chisso Corp シクロヘキセンジオール誘導体
US6730144B2 (en) * 1996-07-25 2004-05-04 Nikki - Universal Co., Ltd. Air purifying filter using modified enzymes
CN1087961C (zh) * 1996-07-25 2002-07-24 日挥通用株式会社 空气净化过滤器
CA2319265A1 (en) 1998-01-26 1999-07-29 Pharm-Eco Laboratories Inc. Enzyme activated supports for enantiomeric separations
DE19931847A1 (de) * 1999-07-09 2001-01-11 Basf Ag Immobilisierte Lipase
CN105002256B (zh) * 2015-08-05 2018-02-23 杭州人可生物制品有限公司 复合酶法拆分制备旋光纯r－（－）坦索洛新的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2437640C3 (de) * 1974-08-05 1978-06-15 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von unlöslichen in Wasser nur wenig quellbaren Polymerisaten von N-Vinyllactamen
DE3138194A1 (de) * 1981-09-25 1983-04-14 Basf Ag, 6700 Ludwigshafen Wasserunloesliches poroeses proteinmaterial, dessen herstellung und verwendung
DE3209224A1 (de) * 1982-03-13 1983-09-15 Basf Ag Verfahren zur herstellung von unloeslichen, nur wenig quellbaren polymerisaten von basischen vinylheterocyclen und deren verwendung
JPS59183691A (ja) * 1983-04-01 1984-10-18 Sumitomo Chem Co Ltd 固定化リパ−ゼの製造法
DK402583D0 (da) * 1983-09-05 1983-09-05 Novo Industri As Fremgangsmade til fremstilling af et immobiliseret lipasepraeparat og anvendelse deraf
DE3344912A1 (de) * 1983-12-13 1985-06-20 Hoechst Ag, 6230 Frankfurt Vernetzte polymerisate, verfahren zu ihrer herstellung und ihre anwendung
US4732853A (en) * 1984-11-21 1988-03-22 President And Fellows Of Harvard College Method of making chiral epoxy alcohols
DE3527014A1 (de) * 1985-07-27 1987-02-05 Basf Ag Verfahren zur immobilisierung von enzymen
US4629742A (en) * 1986-01-27 1986-12-16 Akzo America Inc. Hydrolysis of fats

Also Published As

Publication number Publication date
EP0315831A2 (de) 1989-05-17
JPH01148187A (ja) 1989-06-09
DE3737335A1 (de) 1989-05-18
EP0315831A3 (en) 1990-04-04
DK613088A (da) 1989-06-28
EP0315831B1 (de) 1992-12-30
US5021345A (en) 1991-06-04
DK613088D0 (da) 1988-11-03
DE3877143D1 (de) 1993-02-11

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