ES2052514T3 - Un procedimiento para la preparacion de composiciones farmaceuticas eficaces contra enfermedades autoinmunes. - Google Patents

Un procedimiento para la preparacion de composiciones farmaceuticas eficaces contra enfermedades autoinmunes.

Info

Publication number
ES2052514T3
ES2052514T3 ES87108976T ES87108976T ES2052514T3 ES 2052514 T3 ES2052514 T3 ES 2052514T3 ES 87108976 T ES87108976 T ES 87108976T ES 87108976 T ES87108976 T ES 87108976T ES 2052514 T3 ES2052514 T3 ES 2052514T3
Authority
ES
Spain
Prior art keywords
pharmaceutical compositions
autoimmune diseases
procedure
preparation
effective pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87108976T
Other languages
English (en)
Inventor
Irun Cohen
Israel Vlodavsky
Amiram Eldor
Yaakov Naparstek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hadassah Medical Organization
Yeda Research and Development Co Ltd
Original Assignee
Hadassah Medical Organization
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hadassah Medical Organization, Yeda Research and Development Co Ltd filed Critical Hadassah Medical Organization
Application granted granted Critical
Publication of ES2052514T3 publication Critical patent/ES2052514T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Soil Working Implements (AREA)
  • Paper (AREA)
  • Fertilizers (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

EL INVENTO SE REFIERE A MEDIOS PARA PREVENIR O RETARDAR EL RECHAZO DE TRANSPLANTES EN SERES HUMANOS Y PARA LA SUAVIZACION DEL MISMO Y PARA EL TRATAMIENTO DE ENFERMEDADES AUTOINMUNES EN SERES HUMANOS. LA COMPOSICION FARMACEUTICA ADECUADA PARA CONSEGUIR LOS FINES ANTERIORMENTE MENCIONADOS SE BASA EN LA HEPARINA, EN LA HEPARINA DESULFATADA, EN LA HEPARINA N ACETILATADA U OTROS DERIVADOS ADECUADOS DE LA HEPARINA. LA DOSIS EFECTIVA ES TAL QUE ES SUSTANCIALMENTE INFERIOR A LA REQUERIDA PARA OBTENER EFECTOS ANTICOAGULANTES EN LOS MAMIFEROS. ES GENERALMENTE DEL ORDEN DE ALREDEDOR DEL 1 AL 10% DE LA DOSIS EFECTIVA ANTICOAGULANTE DE TALES COMPUESTOS.
ES87108976T 1986-06-26 1987-06-23 Un procedimiento para la preparacion de composiciones farmaceuticas eficaces contra enfermedades autoinmunes. Expired - Lifetime ES2052514T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL79254A IL79254A0 (en) 1986-06-26 1986-06-26 Compositions for preventing graft rejection

Publications (1)

Publication Number Publication Date
ES2052514T3 true ES2052514T3 (es) 1994-07-16

Family

ID=11056896

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87108976T Expired - Lifetime ES2052514T3 (es) 1986-06-26 1987-06-23 Un procedimiento para la preparacion de composiciones farmaceuticas eficaces contra enfermedades autoinmunes.

Country Status (10)

Country Link
EP (1) EP0251134B1 (es)
JP (1) JP2527749B2 (es)
AT (1) ATE82502T1 (es)
AU (1) AU608228B2 (es)
DE (1) DE3782686T2 (es)
DK (1) DK169422B1 (es)
ES (1) ES2052514T3 (es)
GR (1) GR3006814T3 (es)
IL (1) IL79254A0 (es)
NO (1) NO872675L (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85145A (en) * 1987-01-23 1994-08-26 Univ Australian Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity
US5541166A (en) * 1987-01-23 1996-07-30 The Australian National University Sulphated polysaccharides having anti-metastatic and/or anti-inflammatory activity
GB8808810D0 (en) * 1988-04-14 1988-05-18 Biopharm Clinical Research Ltd Heparin-containing formulations
IL86753A0 (en) * 1988-06-15 1988-11-30 Hadassah Med Org Pharmaceutical compositions for treatment of lupus
DE3821271A1 (de) * 1988-06-23 1989-12-28 Solco Basel Ag Derivatisiertes heparin, verfahren zu dessen herstellung und arzneimittel, welches dieses enthaelt
IL88554A0 (en) * 1988-12-01 1989-07-31 Hadassah Med Org Compositions containing a compound binding to a heparin receptor
US5158940A (en) * 1990-02-14 1992-10-27 The United States Government As Represented By The Secretary, Dhhs Use of suramin to treat rheumatologic diseases
DE69835016T2 (de) * 1997-07-14 2007-06-28 Muramatsu, Takashi, Nagoya Verwendung von midkin oder von anti-midkin antikörper
US6538028B1 (en) 2000-02-01 2003-03-25 Vanderbilt University Method for inhibiting complement activation
CN1197587C (zh) * 2000-06-09 2005-04-20 中国科学院上海细胞生物学研究所 N－位脱硫酸肝素在预防和治疗炎症中的应用
MXPA04002217A (es) 2001-09-12 2004-07-08 Sigma Tau Ind Farmaceuti Derivados de glucosaminoglucanas parcialmente desulfatados como inhibidores de heparanasa, dotados con actividad antiangiogenica y libres de efectos anticoagulantes.
EP1748781B1 (en) 2004-05-27 2012-12-19 Baxter International Inc. Methods for treating bleeding disorders using sulfated polysaccharides
EP2326334A2 (en) 2008-08-22 2011-06-01 Baxter Healthcare SA Methods for treating bleeding disorders
AU2011205271B2 (en) 2010-01-14 2014-01-30 Baxalta GmbH Methods and compositions for treating bleeding disorders
WO2013012954A2 (en) 2011-07-19 2013-01-24 Baxter International Inc. Resorption enhancers as additives to improve the oral formulation of non-anticoagulant sulfated polysaccharides
EP2885642B1 (en) 2012-08-14 2019-05-15 Baxalta GmbH Methods and systems for screening compositions comprising non-anticoagulant sulfated polysaccharides
US9265791B2 (en) 2013-03-12 2016-02-23 Baxalta GmbH Resorption enhancers as additives to improve the oral formulation of low molecular weight heparins
SE538503C2 (en) 2014-11-11 2016-08-16 Tx Medic Ab New dextran sulfate
CN108367023B (zh) * 2015-06-11 2021-04-20 马斯特里赫特大学 预防宿主中移植物衰竭的方法

Also Published As

Publication number Publication date
DE3782686T2 (de) 1993-06-09
JPS6388127A (ja) 1988-04-19
JP2527749B2 (ja) 1996-08-28
ATE82502T1 (de) 1992-12-15
NO872675D0 (no) 1987-06-25
GR3006814T3 (es) 1993-06-30
DK169422B1 (da) 1994-10-31
AU608228B2 (en) 1991-03-28
EP0251134B1 (en) 1992-11-19
IL79254A0 (en) 1986-09-30
EP0251134A3 (en) 1989-05-03
DE3782686D1 (de) 1992-12-24
AU7470687A (en) 1988-01-07
EP0251134A2 (en) 1988-01-07
DK331287D0 (da) 1987-06-26
NO872675L (no) 1987-12-28
DK331287A (da) 1987-12-27

Similar Documents

Publication Publication Date Title
ES2052514T3 (es) Un procedimiento para la preparacion de composiciones farmaceuticas eficaces contra enfermedades autoinmunes.
DE3587266T2 (de) Verfahren und system zur entfernung von immunosuppressiven bestandteilen aus saeugetierblut.
ES2152998T3 (es) Agente anticomplementario obtenido a partir de fucanos de algas pardas.
ATE190496T1 (de) Behandlung von autoimmunkrankheiten durch verabreichung von autoantigenen in form von aerosol
DK602387D0 (da) Fremgangsmaade til fremstilling af glucosaminer med lav molekylvaegt og anvendelse af saadanne glucosaminer
AU560251B2 (en) Pharmaceutical compositions of mopidamol
BR8802852A (pt) Processo para a preparacao de compostos,processo para a preparacao de uma composicao,processo e composicoes para combater ou impedir uma infestacao das plantas
ATE10340T1 (de) Stabilisierung der aktivitaet des faktors viii im blutplasma.
DE69009684T2 (de) Pharmazeutische Zusammensetzungen zur Behandlung gastrointestinaler Störungen.
EP0711134A4 (en) PROTECTIVE MEDICINE AGAINST NEUROLOGICAL ALTERATIONS
DE3584560D1 (de) Arzneimittelzusammensetzung geeignet zur behandlung oder prophylaxe von herzstoerungen.
DK0506658T3 (da) Sammensætninger og fremgangsmåde til behandling af smertefulde, inflammatoriske eller allergiske lidelser
DE68929388D1 (de) Aus Harn isolierte antikoagulierende Verbindung
DK416089D0 (da) Heparinfragmenter og -fraktioner med anti-hiv virkning
ZA9010080B (en) 4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol-3-ones and their use as anticonvulsants
GR3017358T3 (en) 5-Aryl-3H-1,2,4-triazol-3-ones and their use as anticonvulsants.
EP0346810A3 (en) Heparin for the treatment of lupus
ES2036174T3 (es) Un procedimiento para la preparacion de una combinacion broncodilatadora de prazosin-pirbuterol.
ES2096559T3 (es) Interferon gamma humano, procedimiento para la preparacion de dicho interferon gamma humano, y su uso.
KR890017363A (ko) 스트로빌루린 유도체, 이들의 제법 및 용도
ZA873928B (en) Topical methotrexate preparation for the treatment of hyperproliferative epithelial disease
ES2100941T3 (es) Uso de cromakalim/brl 38227 para el tratamiento de la hiperreactividad de las vias respiratorias.
Kaiser Importance of corticosteroids in the treatment of infectious diseases.
ES2106922T3 (es) 3-beta-derivados de digitoxigenina y dihidrodigitoxigenina y composiciones farmaceuticas que los contienen para el tratamiento de la hipertension.
Kim et al. Colles' Fracture Treated with Radial Slab or U-cast

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 251134

Country of ref document: ES