ES2052471T1 - Preparacion farmaceutica fijante de acido gastrico. - Google Patents

Preparacion farmaceutica fijante de acido gastrico.

Info

Publication number
ES2052471T1
ES2052471T1 ES90912814T ES90912814T ES2052471T1 ES 2052471 T1 ES2052471 T1 ES 2052471T1 ES 90912814 T ES90912814 T ES 90912814T ES 90912814 T ES90912814 T ES 90912814T ES 2052471 T1 ES2052471 T1 ES 2052471T1
Authority
ES
Spain
Prior art keywords
acid
pct
active substance
effervescent system
date mar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES90912814T
Other languages
English (en)
Other versions
ES2052471T3 (es
Inventor
Gerhard Gergely
Thomas Gergely
Irmgard Gergely
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES2052471T1 publication Critical patent/ES2052471T1/es
Application granted granted Critical
Publication of ES2052471T3 publication Critical patent/ES2052471T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/29Antimony or bismuth compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/245Bismuth; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

UN GRANULADO, POSIBLEMENTE COMPRIMIDO A MODO DE PASTILLAS, CONTIENE AL MENOS UN ENLACE COMPLEJO, INDISOLUBLE O UN MATERIAL A PENAS DISOLUBLE EN POLVO, QUE PUEDE FIJAR O NEUTRALIZAR ACIDOS, Y QUE NO REACCIONA CON EL ACIDO DEL SISTEMA EFERVESCENTE, Y UN SISTEMA EFERVESCENTE, QUE CONSISTE EN AL MENOS UN ACIDO COMESTIBLE, ORGANICO Y AL MENOS UN CARBONATO ALCALINO O ALCALINOTERREO Y/O BICARBONATO. EL MATERIAL ACTIVO SE ENCUENTRA PRESENTE EN UNA CANTIDAD DEL 5 AL 50%, PREFERENTEMENTE DEL 8 AL 30%, Y EN PARTICULAR DEL 12 AL 25% EN PESO. TIENE UN POLVO FIJADOR DE ACIDO DE ENTRE 2 Y 40, PREFERENTEMENTE 3,5 A 25 MEQ/G, NO REACCIONA CON EL ACIDO DEL SISTEMA EFERVESCENTE Y ELEVA EL VALOR DEL PH EN 0,1 N HCL DURANTE 2 MIN. HASTA UN MAXIMO DE 0,5. CONSISTE EN PARTICULAR EN TRISILICATO DE MAGNESIO, SUCRALFATO Y/O UNA SAL DE BISMUTO. CADA GRANULO CONTIENE AL MENOS UN COMPONENTE ACIDO, AL MENOS UN COMPONENTE DE CARBONATO Y AL MENOS UN MATERIAL ACTIVO ENLAZADO A OTRO. LA FIJACION DE LOS COMPONENTES GRANULADOS ENTRE SI ES EFECTUADA POR UN PRODUCTO DE REACCION DE UN ACIDO CON UN COMPONENTE DE CARBONATO Y/O POR AL MENOS UN HIDROCOLOIDE, EN PARTICULAR XANTANO, MALTODEXTRINA, GALACTOMANANO Y/O TRAGACANTO.
ES90912814T 1989-09-07 1990-09-06 Preparado farmaceutico fijador del acido gastrico. Expired - Lifetime ES2052471T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH326089 1989-09-07
CH336689 1989-09-15
CH53290 1990-02-20

Publications (2)

Publication Number Publication Date
ES2052471T1 true ES2052471T1 (es) 1994-07-16
ES2052471T3 ES2052471T3 (es) 1994-12-16

Family

ID=27172187

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90912814T Expired - Lifetime ES2052471T3 (es) 1989-09-07 1990-09-06 Preparado farmaceutico fijador del acido gastrico.

Country Status (9)

Country Link
US (1) US5260304A (es)
EP (1) EP0490920B1 (es)
JP (1) JP2907299B2 (es)
AT (1) ATE98122T1 (es)
DE (1) DE59003811D1 (es)
DK (1) DK0490920T3 (es)
ES (1) ES2052471T3 (es)
FI (1) FI100855B (es)
WO (1) WO1991003241A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
NL9220009A (nl) * 1991-01-30 1993-11-01 Wellcome Found In water-dispergeerbare tabletten.
US5447918A (en) * 1992-07-27 1995-09-05 Mccullough; Ricky W. Gastrointestinal anti-irritant composition comprising sucralfate and methods of use
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
FR2703250A1 (fr) * 1993-03-30 1994-10-07 Chicouri Marcel Nouvelles compositions pharmaceutiques à base de bismuth et leur procédé de préparation.
US5993860A (en) * 1993-06-17 1999-11-30 Venture Lending NSADI delivery employing a powdered hydrocolloid gum obtainable from higher plants
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
US5399356A (en) * 1994-03-24 1995-03-21 The Procter & Gamble Company Process for making solid dose forms containing bismuth
US5834002A (en) 1994-05-02 1998-11-10 Josman Laboratories, Inc. Chewing gum containing colloidal bismuth subcitrate
US6426085B1 (en) 1994-05-02 2002-07-30 Josman Laboratories Inc. Use of bismuth-containing compounds in topical oral dosage forms for the treatment of halitosis
US6902738B2 (en) * 1994-05-02 2005-06-07 Josman Laboratories, Inc. Topical oral dosage forms containing bismuth compounds
GB9501560D0 (en) * 1995-01-26 1995-03-15 Nycomed Imaging As Contrast agents
HUP9900428A2 (hu) * 1995-01-26 1999-06-28 Nycomed Imaging A/S Bizmutvegyületek, ezeket tartalmazó diagnosztikai kontrasztanyag, ennek alkalmazása és ezt tartalmazó gyógyászati készítmény
EP0808629A4 (en) * 1995-02-02 1998-03-04 Chugai Pharmaceutical Co Ltd PREPARATION OF SUCRALFATE
US6372784B1 (en) 1995-02-07 2002-04-16 Josman Laboratories, Inc. Bismuth-containing compounds in topical dosage forms for treatment of corneal and dermal wounds
US6379651B1 (en) 1995-02-07 2002-04-30 Josman Laboratories Oral-topical dosage forms for delivering antibacterials/antibiotics to oral cavity to eradicate H. pylori as a concomitant treatment for peptic ulcers and other gastro-intestinal diseases
KR19980703526A (ko) * 1995-04-03 1998-11-05 나가야마오사무 수크랄페이트 함유 제제 조성물
KR20000019144A (ko) * 1998-09-09 2000-04-06 이수근 태양전지를이용한휴대용다중전원장치
US6683043B1 (en) * 1998-12-08 2004-01-27 The Procter & Gamble Company Process for manufacturing effervescence components
US20040142903A1 (en) * 2003-01-16 2004-07-22 Par Pharmaceutical Inc. Bioavailable fenofibrate compositions, methods for treating hyperlipidemia and hypercholesterolemia and processes for the preparation of such compositions
US8216610B2 (en) 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
AU2006317530B2 (en) 2005-11-28 2011-09-01 Imaginot Pty Ltd Oral therapeutic compound delivery system
DE102006054260A1 (de) * 2006-02-28 2007-09-27 Lohmann Animal Health Gmbh & Co. Kg Wasser stabilisierende Zusammensetzung, Verfahren zu deren Herstellung und deren Verwendung
KR20170003414A (ko) * 2015-06-30 2017-01-09 (주)아모레퍼시픽 속붕해형 과립환 모발 세정용 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB514888A (en) * 1937-03-20 1939-11-21 Alfred Washington Pauley Effervescent composition containing magnesium hydroxide and method of making same
GB524756A (en) * 1938-03-17 1940-08-14 Chas H Phillips Chemical Co Medicinal preparations of magnesium hydroxide and precess of obtaining the same
AU1087883A (en) * 1982-02-02 1983-08-11 Bayer Aktiengesellschaft Water dispersible, soluble granules
US4678661A (en) * 1983-09-28 1987-07-07 Gerhard Gergely Effervescent composition and method of making same
DE3440288A1 (de) * 1984-11-05 1986-05-07 Gergely, Gerhard, Dr.-Ing., Wien Pharmazeutische zubereitung mit einem gehalt an mindestens einer schleimhautreizenden substanz oder dergleichen, insbesondere profen, sowie verfahren zu ihrer herstellung
DE3627475A1 (de) * 1986-06-26 1988-01-14 Gergely Gerhard Verfahren zum herstellen eines brausegranulates, danach hergestelltes brausegranulat sowie dessen verwendung
US4801454A (en) * 1986-07-17 1989-01-31 The Proctor & Gamble Company Processes for making colored pharmaceutical compositions
DK179687D0 (da) * 1987-04-08 1987-04-08 Farma Food As Praeparat

Also Published As

Publication number Publication date
JPH05500052A (ja) 1993-01-14
FI100855B (fi) 1998-03-13
JP2907299B2 (ja) 1999-06-21
WO1991003241A1 (de) 1991-03-21
EP0490920B1 (de) 1993-12-08
DK0490920T3 (da) 1994-04-25
FI910802A0 (fi) 1991-02-19
DE59003811D1 (de) 1994-01-20
ATE98122T1 (de) 1993-12-15
US5260304A (en) 1993-11-09
EP0490920A1 (de) 1992-06-24
ES2052471T3 (es) 1994-12-16

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