ES2051977T3 - Procedimiento para la inmovilizacion de proteinas en una fase solida, fase solida que soporta las proteinas asi producidas, asi como su empleo. - Google Patents

Procedimiento para la inmovilizacion de proteinas en una fase solida, fase solida que soporta las proteinas asi producidas, asi como su empleo.

Info

Publication number
ES2051977T3
ES2051977T3 ES89123321T ES89123321T ES2051977T3 ES 2051977 T3 ES2051977 T3 ES 2051977T3 ES 89123321 T ES89123321 T ES 89123321T ES 89123321 T ES89123321 T ES 89123321T ES 2051977 T3 ES2051977 T3 ES 2051977T3
Authority
ES
Spain
Prior art keywords
solid phase
proteins
procedure
well
immobilization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89123321T
Other languages
English (en)
Inventor
Josef Maier
Dieter Dr Rer Nat Mangold
Reiner Dr Schlipfenbacher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2051977T3 publication Critical patent/ES2051977T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/813—Carrier is a saccharide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/813—Carrier is a saccharide
    • Y10S530/814—Cellulose or derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer
    • Y10S530/817—Entrapped within the carrier, e.g. gel, hollow fibre

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

EL OBJETO DEL INVENTO LO CONSTITUYEN UN PROCEDIMIENTO PARA INMOVILIZAR A UNA PROTEINA SOBRE UNA FASE SOLIDA, CARACTERIZADO PORQUE SE AGREGA LA PROTEINA A INMOVILIZAR, SE PONE EN CONTACTO CON UNA FASE HIDROFILA EN EL SENO DE UN LIQUIDO Y, UNA VEZ REALIZADO EL CONTACTO, SE SECA LA FASE SOLIDA, ASI COMO TAMBIEN UNA FASE SOLIDA OBTENIDA DE ESTE MODO QUE CONTENGA UNA PROTEINA UNIDA DE FORMA NO COVALENTE Y SU UTILIZACION PARA REALIZAR VALORACIONES ANALITICAS.
ES89123321T 1988-12-19 1989-12-16 Procedimiento para la inmovilizacion de proteinas en una fase solida, fase solida que soporta las proteinas asi producidas, asi como su empleo. Expired - Lifetime ES2051977T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3842700A DE3842700A1 (de) 1988-12-19 1988-12-19 Verfahren zur proteinimmobilisierung an einer festphase, so hergestellte protein tragende festphase sowie deren verwendung

Publications (1)

Publication Number Publication Date
ES2051977T3 true ES2051977T3 (es) 1994-07-01

Family

ID=6369520

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89123321T Expired - Lifetime ES2051977T3 (es) 1988-12-19 1989-12-16 Procedimiento para la inmovilizacion de proteinas en una fase solida, fase solida que soporta las proteinas asi producidas, asi como su empleo.

Country Status (8)

Country Link
US (1) US5310885A (es)
EP (1) EP0374778B1 (es)
JP (1) JPH087213B2 (es)
AT (1) ATE103936T1 (es)
AU (1) AU607088B2 (es)
CA (1) CA2005926C (es)
DE (2) DE3842700A1 (es)
ES (1) ES2051977T3 (es)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5512169A (en) * 1992-12-30 1996-04-30 Dow Corning Corporation Liquid column packing materials
US5599660A (en) * 1993-01-19 1997-02-04 Pharmacia Biotech Inc. Method and preparation for sequential delivery of wax-embedded, inactivated biological and chemical reagents
BR9607204A (pt) 1995-03-14 1997-11-11 Kimberly Clark Co Artigo umedecivel
ES2184236T3 (es) 1997-02-06 2003-04-01 Therasense Inc Sensor in vitro de analitos de pequeño volumen.
IL121116A (en) * 1997-06-19 2000-12-06 Savyon Diagnostics Ltd Stabilization of polypeptides for use in immunoassay procedures
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6251260B1 (en) 1998-08-24 2001-06-26 Therasense, Inc. Potentiometric sensors for analytic determination
US6591125B1 (en) 2000-06-27 2003-07-08 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
US6338790B1 (en) 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
KR100307294B1 (ko) * 1998-12-29 2001-12-17 김영환 반도체장치의제조방법
AU5747100A (en) 1999-06-18 2001-01-09 Therasense, Inc. Mass transport limited in vivo analyte sensor
US6616819B1 (en) 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
GB0016836D0 (en) * 2000-07-07 2000-08-30 Lee Helen Improved dipstick assays (1)
US6528325B1 (en) * 2000-10-13 2003-03-04 Dexall Biomedical Labs, Inc. Method for the visual detection of specific antibodies in human serum by the use of lateral flow assays
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US7041468B2 (en) 2001-04-02 2006-05-09 Therasense, Inc. Blood glucose tracking apparatus and methods
AU2003303597A1 (en) 2002-12-31 2004-07-29 Therasense, Inc. Continuous glucose monitoring system and methods of use
US7587287B2 (en) 2003-04-04 2009-09-08 Abbott Diabetes Care Inc. Method and system for transferring analyte test data
FR2855177B1 (fr) * 2003-05-23 2005-07-08 Raymond Robert Composition contenant des acides nucleiques lyophilises en presence de collagene et de disaccharides
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
EP1718198A4 (en) 2004-02-17 2008-06-04 Therasense Inc METHOD AND SYSTEM FOR PROVIDING DATA COMMUNICATION IN A CONTINUOUS BLOOD SUGAR MONITORING AND MANAGEMENT SYSTEM
US7393453B2 (en) * 2004-06-23 2008-07-01 Kham Lin Method for analysis of perchlorate
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
WO2007143225A2 (en) 2006-06-07 2007-12-13 Abbott Diabetes Care, Inc. Analyte monitoring system and method
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US20100213057A1 (en) 2009-02-26 2010-08-26 Benjamin Feldman Self-Powered Analyte Sensor
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
US9184490B2 (en) 2009-05-29 2015-11-10 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
WO2011026148A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
EP2473098A4 (en) 2009-08-31 2014-04-09 Abbott Diabetes Care Inc ANALYTICAL SIGNAL PROCESSING APPARATUS AND METHOD
WO2011041469A1 (en) 2009-09-29 2011-04-07 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
US9980669B2 (en) 2011-11-07 2018-05-29 Abbott Diabetes Care Inc. Analyte monitoring device and methods
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4004979A (en) * 1968-03-29 1977-01-25 Agence Nationale De Valorisation De La Recherche (Anvar) Preparation of active proteins cross-linked to inactive proteins
US4081329A (en) * 1972-12-08 1978-03-28 Boehringer Mannheim Gmbh Preparation of carrier-bound macromolecular compounds
BE821053A (fr) * 1974-08-01 1975-04-14 Produit pour diagnostic par determination immunochimique
CA1056746A (en) * 1974-09-06 1979-06-19 Chung J. Lai Biologically active membrane material
JPS6057127B2 (ja) * 1976-09-28 1985-12-13 富士写真フイルム株式会社 磁気記録媒体
US4338398A (en) * 1979-03-20 1982-07-06 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Immobilization of starch degrading enzymes
US4410634A (en) * 1979-10-26 1983-10-18 Dynasciences Corporation Method of passively adsorbing immuno-reactive haptens to solid phases
US4461829A (en) * 1981-09-14 1984-07-24 Miles Laboratories, Inc. Homogeneous specific binding assay element and lyophilization production method
JPS5875063A (ja) * 1981-10-30 1983-05-06 Japan Synthetic Rubber Co Ltd 免疫学的診断試薬の製造方法
FR2543972B1 (fr) * 1983-04-06 1985-12-27 Immunotech Sa Procede de fixation de macromolecules biologiques sur des supports
JPS59224565A (ja) * 1983-04-28 1984-12-17 Morinaga Milk Ind Co Ltd 抗原検出用試薬
IL75828A (en) * 1985-07-17 1991-06-10 Univ Ramot Immobilization by biologically active proteins
US4742158A (en) * 1986-04-25 1988-05-03 Merck & Co., Inc. Purification of hepatitis pre-S antigens by polymerized serum albumin affinity binding
US4794090A (en) * 1986-09-26 1988-12-27 W. R. Grace & Co.-Conn. Immobilization support for biologicals
DE3640412A1 (de) * 1986-11-26 1988-06-09 Boehringer Mannheim Gmbh Verfahren zur bestimmung einer spezifisch bindefaehigen substanz
DE3725504A1 (de) * 1987-07-31 1989-02-09 Thraenhart Olaf Priv Doz Dr Verfahren und vorrichtung zum nachweis von antikoerpern und antigenen
JPH04501313A (ja) * 1988-10-11 1992-03-05 クールター　コーポレイション 新規な生体適合性中間コーティングを有する免疫反応体キャリアー及びその製造方法

Also Published As

Publication number Publication date
US5310885A (en) 1994-05-10
EP0374778A3 (de) 1991-10-09
JPH087213B2 (ja) 1996-01-29
DE58907404D1 (de) 1994-05-11
CA2005926A1 (en) 1990-06-19
EP0374778B1 (de) 1994-04-06
DE3842700A1 (de) 1990-06-21
CA2005926C (en) 1999-11-16
JPH02262600A (ja) 1990-10-25
AU607088B2 (en) 1991-02-21
AU4616589A (en) 1990-06-21
ATE103936T1 (de) 1994-04-15
EP0374778A2 (de) 1990-06-27

Similar Documents

Publication Publication Date Title
ES2051977T3 (es) Procedimiento para la inmovilizacion de proteinas en una fase solida, fase solida que soporta las proteinas asi producidas, asi como su empleo.
AT352256B (de) Behaelter zur aufnahme und aufbewahrung von blut u.dgl.
ES491654A0 (es) Perfeccionamientos en las juntas de carrocera,especialmente de automoviles
ATE7920T1 (de) Rapamycin-derivate.
NL190397B (nl) Dialysesonde voor toepassing in een biologisch weefsel, zoals hersenweefsel.
IT7951016A0 (it) Veicolo farmaceutico a base di gliceridi e sostanze organiche e composizione farmaceutica che lo contiene
BR8004905A (pt) Protese de valvula cardiaca
ES268587Y (es) Perfeccionamientos introducidos en la estructuracion de calzados especialmente los de uso deportivo.
NL182733B (nl) Kunststofsamenstelling, alsmede gevormd voortbrengsel geheel of gedeeltelijk bestaande uit, respectievelijk verkregen onder toepassing van deze kunststofsamenstelling.
ES523145A0 (es) Mejoras introducidas en el procedimiento de fabricacion de acumuladores.
ES497684A0 (es) Valvula de retencion mecano-accionada
SE7707889L (sv) Haptoglobinpreparat
SU462015A1 (ru) Расширитель
SU621529A1 (ru) Выдвижной призматический рукав с направл ющими качени
BR7302546D0 (pt) Colar de aperto com dispositivo tensor colar de aperto com dispositivo tensor
IT8604764V0 (it) Sex-collant,guaina-collantanatomica,riposante in pizzo bielastico con elastomero
FI47463C (fi) Tapa valmistaa varsinkin vaneriliimoihin tasaisesti sekoittuvia lahone sto- ja/tai hyönteissuoja-aineita.
BE865258A (fr) Pansement ou bandage rapide
IT8559841V0 (it) Suoletta con calzino in pelle morbida.
IT8809341A0 (it) Filato comune incamiciato divera pelle
ES243931Y (es) Dispositivo de fijacion de patas en somieres.
BR7204085D0 (pt) Aplicacao decorativa em biqueiras de calcados
ES518097A0 (es) Procedimiento de homogeneizacion en la fabricacion de zapatillas y calzados similares.
ES1012971Y (es) Dispositivo para medir el grado de rigidez del pene.
KR870018034U (ko) 내대를 삽설케한 안대

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 374778

Country of ref document: ES