ES2051707T3 - Implantes para la liberacion de macromoleculas bioactivas. - Google Patents

Implantes para la liberacion de macromoleculas bioactivas.

Info

Publication number
ES2051707T3
ES2051707T3 ES87106859T ES87106859T ES2051707T3 ES 2051707 T3 ES2051707 T3 ES 2051707T3 ES 87106859 T ES87106859 T ES 87106859T ES 87106859 T ES87106859 T ES 87106859T ES 2051707 T3 ES2051707 T3 ES 2051707T3
Authority
ES
Spain
Prior art keywords
implants
release
bioactive macromolecules
bioactive
macromolecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87106859T
Other languages
English (en)
Inventor
Paul Y Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4133165&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2051707(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2051707T3 publication Critical patent/ES2051707T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Abstract

LA INVENCION TRATA DE PREPARACIONES PARA IMPLANTACION CAPACES DE MOSTRAR ACCION PROLONGADA CUANDO SE INSERTAN, QUE ESTAN CONSTITUIDAS POR POLVO DE SUSTANCIAS LIPOIDES NATURALES MEZCLADAS CON MACROMOLECULAS BIOACTIVAS, QUE DESPUES SE COMPRIMEN EN FORMA DE DISCO O VARILLA QUE PUEDE TROCEARSE Y UTILIZARSE EN TROCITOS PEQUEÑOS.
ES87106859T 1986-05-20 1987-05-12 Implantes para la liberacion de macromoleculas bioactivas. Expired - Lifetime ES2051707T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000509526A CA1257199A (en) 1986-05-20 1986-05-20 Preparation containing bioactive macromolecular substance for multi-months release in vivo

Publications (1)

Publication Number Publication Date
ES2051707T3 true ES2051707T3 (es) 1994-07-01

Family

ID=4133165

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87106859T Expired - Lifetime ES2051707T3 (es) 1986-05-20 1987-05-12 Implantes para la liberacion de macromoleculas bioactivas.

Country Status (10)

Country Link
US (2) US5110595A (es)
EP (1) EP0246540B1 (es)
JP (1) JPS6322012A (es)
AT (1) ATE79024T1 (es)
AU (1) AU603793B2 (es)
CA (1) CA1257199A (es)
DE (1) DE3780862T2 (es)
DK (1) DK251287A (es)
ES (1) ES2051707T3 (es)
GR (1) GR3005395T3 (es)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863736A (en) * 1987-03-16 1989-09-05 Monsanto Company Somatotropin prolonged release
US5688519A (en) * 1987-04-06 1997-11-18 Leonard; Robert J. Flash-flow fused medicinal implants
EP0353045B1 (en) * 1988-07-26 1995-11-15 Rutgers, The State University of New Jersey Devices and methods for growth promotion in poultry roasters
WO1990010437A1 (en) * 1989-03-09 1990-09-20 Endocon, Inc. Partially fused peptide pellet
DE3919982A1 (de) * 1989-06-19 1990-12-20 Liedtke Pharmed Gmbh Orale lipidarzneiform
AU6430190A (en) * 1989-10-10 1991-05-16 Pitman-Moore, Inc. Sustained release composition for macromolecular proteins
NZ237084A (en) * 1990-02-12 1993-10-26 Lucky Ltd Composition for the prolonged release of somatotropin comprising the somatotropin, a tocopherol component, and an assistant delaying agent
WO1992014449A1 (en) * 1991-02-20 1992-09-03 Nova Pharmaceutical Corporation Controlled release microparticulate delivery system for proteins
US5801141A (en) * 1991-06-24 1998-09-01 American Cyanamid Company Implant compositions containing a biologically active protein, peptide or polypeptide
SG47955A1 (en) * 1991-06-24 1998-04-17 American Cyanamid Co Implant compositions containing a biologically active protein peptide or polypeptide
YU87892A (sh) * 1991-10-01 1995-12-04 Eli Lilly And Company Lilly Corporate Center Injektibilne formulacije produženog otpuštanja i postupci za njihovo dobijanje i primenu
US5374616A (en) * 1991-10-18 1994-12-20 Georgetown University Compositions containing sphingosylphosphorylcholine and the use thereof as a cellular growth factor
KR100260632B1 (ko) * 1992-12-28 2000-07-01 성재갑 이식형 소마토트로핀 조성물
JPH07112940A (ja) * 1993-08-26 1995-05-02 Takeda Chem Ind Ltd 徐放性非経口投与製剤およびその製造方法
GB9325445D0 (en) 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
US5449679A (en) * 1994-07-29 1995-09-12 Leonard; Robert J. Process and products for reducing biological fluid levels of a lipid soluble waste
USRE40546E1 (en) * 1996-05-01 2008-10-21 Scarista, Ltd. 1,3-Propane diol esters and ethers and methods for their use in drug delivery
DK0823897T3 (da) * 1995-05-01 2004-12-06 Scarista Ltd Nicotinsyreestere og farmaceutiske præparater indeholdende disse
MY118354A (en) * 1995-05-01 2004-10-30 Scarista Ltd 1,3-propane diol derivatives as bioactive compounds
AUPN366795A0 (en) * 1995-06-20 1995-07-13 Peptide Technology Limited Formulation for preventing reproductive function
US5827904A (en) * 1996-09-27 1998-10-27 Hahn; David Medical implant composition
GB9705102D0 (en) * 1997-03-12 1997-04-30 Scotia Holdings Inc Presentation of fatty acids
US5874098A (en) * 1997-05-28 1999-02-23 Ivy Laboratories, Inc. Pellet implant system
GB9723068D0 (en) * 1997-10-31 1998-01-07 Patel Atulkumar S A skin-moisturing preparation
KR19990071255A (ko) 1998-02-28 1999-09-15 성재갑 소마토트로핀과 비타민의 합제 조성물
US6263880B1 (en) 1998-06-22 2001-07-24 Neovasys, Inc. Method of enhancing blood flow in tissue
US20010033839A1 (en) * 1999-10-04 2001-10-25 Emilio Barbera-Guillem Vaccine and immunotherapy for solid nonlymphoid tumor and related immune dysregulation
US6488649B1 (en) 1998-11-24 2002-12-03 Edward M. Lichten Implant device
RU2271196C2 (ru) * 1999-06-04 2006-03-10 Элзэ Копэрейшн Имплантируемая композиция (варианты) и способ ее приготовления
JP2001058955A (ja) * 1999-06-17 2001-03-06 Inst Of Physical & Chemical Res 生理活性ペプチド徐放性製剤
CN1278438C (zh) 2000-09-25 2006-10-04 三星Sdi株式会社 用于可充电锂电池的正电极活性材料及其制备方法
GB0121709D0 (en) * 2001-09-07 2001-10-31 Imp College Innovations Ltd Food inhibition agent
EP2050460A1 (en) * 2001-09-24 2009-04-22 Imperial Innovations Limited PYY and agonists thereof for modification of feeding behaviour
JP4733922B2 (ja) 2002-01-10 2011-07-27 インペリアル・イノベ−ションズ・リミテッド 摂食行動の修正
US8058233B2 (en) * 2002-01-10 2011-11-15 Oregon Health And Science University Modification of feeding behavior using PYY and GLP-1
GB0300571D0 (en) * 2003-01-10 2003-02-12 Imp College Innovations Ltd Modification of feeding behaviour
KR100486028B1 (ko) * 2004-04-20 2005-05-03 주식회사 펩트론 단백질 함유 서방성 리피드 임플란트 및 이의 제조방법
CA2910494C (en) 2004-07-19 2018-10-23 Biocon Limited Insulin-oligomer conjugates, formulations and uses thereof
AU2005325213B2 (en) * 2004-08-04 2010-10-07 Evonik Corporation Methods for manufacturing delivery devices and devices thereof
WO2006134340A2 (en) 2005-06-13 2006-12-21 Imperial Innovations Limited Oxyntomodulin analogues and their effects on feeding behaviour
GB0511986D0 (en) * 2005-06-13 2005-07-20 Imp College Innovations Ltd Novel compounds and their effects on feeding behaviour
CA3163418A1 (en) 2006-10-06 2008-05-22 Jeffrey S. Isenberg Prevention of tissue ischemia, related methods and compositions
TWI428346B (zh) 2006-12-13 2014-03-01 Imp Innovations Ltd 新穎化合物及其等對進食行為影響
RU2506273C2 (ru) 2007-07-09 2014-02-10 Импиэриэл Инноувейшнс Лимитид Аналог панкреатического полипептида человека (варианты), фармацевтическая композиция на его основе, способ лечения ожирения или диабета, способ снижения аппетита, уменьшения поглощения пищи или снижения потребления калорий и способ косметического снижения массы посредством указанного аналога
MX2010003979A (es) 2007-10-16 2010-06-02 Biocon Ltd Composicion farmaceutica oralmente administrable y proceso para su preparacion.
ES2718612T3 (es) 2007-12-20 2019-07-03 Evonik Corp Procedimiento para preparar micropartículas que tienen un bajo volumen de disolvente residual
JP2010229284A (ja) 2009-03-27 2010-10-14 Fujifilm Corp 光硬化性組成物
GB0918579D0 (en) 2009-10-22 2009-12-09 Imp Innovations Ltd Gadd45beta targeting agents
GB201001333D0 (en) 2010-01-27 2010-03-17 Imp Innovations Ltd Novel compounds and their effects on feeding behaviour
GB201101459D0 (en) 2011-01-27 2011-03-16 Imp Innovations Ltd Novel compounds and thier effects on fedding behaviour
US9944687B2 (en) 2011-07-04 2018-04-17 Imperial Innovations Limited Compounds and their effects on feeding behaviour
WO2013039916A1 (en) 2011-09-12 2013-03-21 The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services Compositions for and methods of treatment and enhanced detection of non-pituitary tumors
US9879012B2 (en) 2012-03-29 2018-01-30 Regents Of The University Of Colorado, A Body Corporate Click nucleic acids
WO2014160183A1 (en) 2013-03-13 2014-10-02 The United States Of America,As Represented By The Secretary,Department Of Health And Human Services Methods for modulating chemotherapeutic cytotoxicity
IL242979B2 (en) 2013-07-02 2023-03-01 Cortice Biosciences Inc A method for treating degenerative nerve diseases
CA2923835C (en) 2013-09-11 2022-11-29 The Administrators Of The Tulane Educational Fund Novel anthranilic amides and the use thereof
WO2015057583A1 (en) 2013-10-14 2015-04-23 The United States Of America, As Represented By The Secretary Treatment of chronic kidney disease with sahps
DE102013018193A1 (de) 2013-10-30 2015-05-13 Martin-Luther-Universität Halle-Wittenberg, Körperschaft des öffentlichen Rechts Injizierbare Depotformulierungen zur kontrollierten Wirkstofffreisetzung
DE102014005782A1 (de) 2014-04-23 2015-10-29 Martin-Luther-Universität Halle-Wittenberg lnjizierbare und implantierbare Trägersysteme auf Basis von modifizierten Poly(dikarbonsäure-multiol estern) zur kontrollierten Wirkstofffreisetzung
WO2015177572A1 (en) 2014-05-23 2015-11-26 Imperial Innovations Limited Peptide yy (pyy) analogues
WO2016164412A1 (en) 2015-04-07 2016-10-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Hypoxia-inducible factor 1 (hif-1) inhibitors
GB201720188D0 (en) 2017-12-04 2018-01-17 Imperial Innovations Ltd Analogues of PYY
GB201908424D0 (en) 2019-06-12 2019-07-24 Imp College Innovations Ltd Novel compounds
GB201908426D0 (en) 2019-06-12 2019-07-24 Imp College Innovations Ltd Appetite suppressing compounds
KR20230125802A (ko) 2020-12-11 2023-08-29 아이피2아이피오 이노베이션스 리미티드 신규 화합물

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2895875A (en) * 1950-10-20 1959-07-21 Erich M H Radde Subcutaneous hormone pellets
US3312594A (en) * 1963-06-21 1967-04-04 Squibb & Sons Inc Longlasting troche
US3887699A (en) * 1969-03-24 1975-06-03 Seymour Yolles Biodegradable polymeric article for dispensing drugs
US4450150A (en) * 1973-05-17 1984-05-22 Arthur D. Little, Inc. Biodegradable, implantable drug delivery depots, and method for preparing and using the same
US4351337A (en) * 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
CA1076480A (en) * 1975-04-28 1980-04-29 John S. Kent Inert core implant pellet
GB1523965A (en) * 1976-03-19 1978-09-06 Ici Ltd Pharmaceutical compositions containing steroids
US4180560A (en) * 1976-10-26 1979-12-25 Syntex Corporation Inert core implant pellet
DE2843963A1 (de) * 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
US4356166A (en) * 1978-12-08 1982-10-26 University Of Utah Time-release chemical delivery system
GB2051574B (en) * 1979-05-10 1984-01-18 Kyoto Pharma Ind Adjuvant for promoting absorption of pharmacologically active substances through the rectum
US4279812A (en) * 1979-09-12 1981-07-21 Seton Company Process for preparing macromolecular biologically active collagen
JPS56122317A (en) * 1980-02-29 1981-09-25 Koken:Kk Drug transporting material and its preparation
JPS56138111A (en) * 1980-03-28 1981-10-28 Teijin Ltd Suppository containing unsaturated fatty acid or salt thereof
US4393041A (en) * 1980-04-25 1983-07-12 International Minerals & Chemical Corp. Fibrin binder/carrier for active biochemical agents
US4322323A (en) * 1980-12-01 1982-03-30 Alza Corporation Erodible device comprising surfactant for modifying the rate of erosion of the device
US4349530A (en) * 1980-12-11 1982-09-14 The Ohio State University Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal
US4483807A (en) * 1981-01-27 1984-11-20 Japan Atomic Energy Research Institute Process for producing a slow release composite
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
SU1011126A1 (ru) * 1981-07-14 1983-04-15 Всесоюзный научно-исследовательский и испытательный институт медицинской техники Средство дл лечени сахарного диабета
NL193099C (nl) * 1981-10-30 1998-11-03 Novo Industri As Gestabiliseerde insuline-oplossing.
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
DD212185A1 (de) * 1982-12-21 1984-08-08 Adw Ddr Verfahren zur herstellung von phospholipid-wirkstoff-kombinationen
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
IL68769A (en) * 1983-05-23 1986-02-28 Hadassah Med Org Pharmaceutical compositions containing insulin for oral administration
US4882167A (en) * 1983-05-31 1989-11-21 Jang Choong Gook Dry direct compression compositions for controlled release dosage forms
CA1196864A (en) * 1983-06-10 1985-11-19 Mattheus F.A. Goosen Controlled release of injectable and implantable insulin compositions
WO1985000372A1 (fr) * 1983-07-01 1985-01-31 Battelle Memorial Institute Polypeptide biodegradable et son utilisation pour le relargage progressif de medicaments
US4774091A (en) * 1983-10-14 1988-09-27 Sumitomo Pharmaceuticals Company, Ltd. Long-term sustained-release preparation
DE3474511D1 (en) * 1983-11-01 1988-11-17 Terumo Corp Pharmaceutical composition containing urokinase
US4744989A (en) * 1984-02-08 1988-05-17 E. R. Squibb & Sons, Inc. Method of preparing liposomes and products produced thereby
DE3413608A1 (de) * 1984-04-11 1985-10-24 Hoechst Ag, 6230 Frankfurt Implantierbare zubereitungen von regulatorischen peptiden mit gesteuerter freisetzung und verfahren zu ihrer herstellung
US4568536A (en) * 1985-02-08 1986-02-04 Ethicon, Inc. Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
US4638045A (en) * 1985-02-19 1987-01-20 Massachusetts Institute Of Technology Non-peptide polyamino acid bioerodible polymers
US4670249A (en) * 1985-04-12 1987-06-02 International Minerals & Chemical Corp. Growth-promoting compositions
DE3523454A1 (de) * 1985-07-01 1987-01-08 Eberhard Prof Dr Nuernberg Formkoerper
IL79681A (en) * 1985-08-12 1991-06-10 Int Minerals & Chem Corp Transition metal complexes of growth hormones and their prolonged release compositions
US4692441A (en) * 1985-08-16 1987-09-08 Merck & Co., Inc. Chorine esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities
US4775659A (en) * 1985-08-19 1988-10-04 Eli Lilly And Company Injectable semi-solid formulations
US4837381A (en) * 1986-08-11 1989-06-06 American Cyanamid Company Compositions for parenteral administration and their use

Also Published As

Publication number Publication date
DE3780862T2 (de) 1993-01-14
US5110595A (en) 1992-05-05
ATE79024T1 (de) 1992-08-15
AU7108987A (en) 1988-09-15
AU603793B2 (en) 1990-11-29
EP0246540A3 (en) 1988-06-08
JPS6322012A (ja) 1988-01-29
DK251287D0 (da) 1987-05-18
US5939380A (en) 1999-08-17
DE3780862D1 (de) 1992-09-10
CA1257199A (en) 1989-07-11
GR3005395T3 (es) 1993-05-24
EP0246540A2 (en) 1987-11-25
DK251287A (da) 1987-11-21
EP0246540B1 (en) 1992-08-05

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