ES2044043T3 - Procedimiento para preparar n-piridinil-9h-carbazol-9-aminas. - Google Patents
Procedimiento para preparar n-piridinil-9h-carbazol-9-aminas.Info
- Publication number
- ES2044043T3 ES2044043T3 ES89123612T ES89123612T ES2044043T3 ES 2044043 T3 ES2044043 T3 ES 2044043T3 ES 89123612 T ES89123612 T ES 89123612T ES 89123612 T ES89123612 T ES 89123612T ES 2044043 T3 ES2044043 T3 ES 2044043T3
- Authority
- ES
- Spain
- Prior art keywords
- rent
- hydrogen
- halogen
- piridinil
- aminas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical class [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000006949 cholinergic function Effects 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen(.) Chemical compound [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/289,887 US4868190A (en) | 1988-12-27 | 1988-12-27 | N-pyridinyl-9H-carbazol-9-amines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2044043T3 true ES2044043T3 (es) | 1994-01-01 |
Family
ID=23113557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89123612T Expired - Lifetime ES2044043T3 (es) | 1988-12-27 | 1989-12-21 | Procedimiento para preparar n-piridinil-9h-carbazol-9-aminas. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4868190A (en:Method) |
| EP (1) | EP0376155B1 (en:Method) |
| JP (1) | JPH0725749B2 (en:Method) |
| KR (1) | KR900009596A (en:Method) |
| AT (1) | ATE79118T1 (en:Method) |
| AU (1) | AU623205B2 (en:Method) |
| CA (1) | CA2006529C (en:Method) |
| DE (1) | DE68902386T2 (en:Method) |
| DK (1) | DK662189A (en:Method) |
| ES (1) | ES2044043T3 (en:Method) |
| FI (1) | FI896243A7 (en:Method) |
| GR (1) | GR3006140T3 (en:Method) |
| IE (1) | IE894175L (en:Method) |
| IL (1) | IL92867A0 (en:Method) |
| NO (1) | NO895222L (en:Method) |
| NZ (1) | NZ231943A (en:Method) |
| PH (1) | PH27122A (en:Method) |
| PT (1) | PT92696A (en:Method) |
| ZA (1) | ZA899904B (en:Method) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4916135A (en) * | 1989-05-08 | 1990-04-10 | Hoechst Roussel Pharmaceuticals Inc. | N-heteroaryl-4-quinolinamines |
| ATE118002T1 (de) * | 1989-08-02 | 1995-02-15 | Hoechst Roussel Pharma | 2,3-dihydro-1-(pyridinylamino)-indole, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel. |
| US5179099A (en) * | 1989-08-02 | 1993-01-12 | Hoechst-Roussel Pharmaceuticals Incorporated | 2,3-dihydro-1-(pyridinylamino)-indoles |
| US4994472A (en) * | 1989-08-02 | 1991-02-19 | Hoechst-Roussel Pharmaceuticals Incorporated | 1-(pyridinylamino)-2-pyrrolidinones as pain relievers |
| US4983608A (en) * | 1989-09-05 | 1991-01-08 | Hoechst-Roussell Pharmaceuticals, Inc. | N-substituted-4-pyrimidinamines and pyrimidinediamines |
| KR100445629B1 (ko) * | 1995-07-27 | 2004-10-14 | 아벤티스 파마슈티칼스 인크. | 비치환및치환된n-(피롤-1-일)피리딘아민의항경련제로서의용도 |
| US5776955A (en) * | 1995-07-27 | 1998-07-07 | Hoechst Marion Roussel, Inc. | Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents |
| ZA989365B (en) * | 1997-10-15 | 1999-04-15 | Boehringer Mannheim Pharm Corp | Preparation for treating alzheimer's disease |
| EP1305082B1 (en) * | 2000-07-21 | 2004-05-26 | Ortho-McNeil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH475982A (de) * | 1966-11-16 | 1969-07-31 | Wander Ag Dr A | Verfahren zur Herstellung von Carbazolderivaten |
| EP0073849A1 (en) * | 1981-09-03 | 1983-03-16 | Schering Corporation | Novel phenyl-1,2,3,4-tetrahydrocarbazoles, their preparation and pharmaceutical compositions containing them |
| US4792562A (en) * | 1985-12-04 | 1988-12-20 | Hoechst-Roussel Pharmaceuticals, Inc. | N-(pyrrol-1-yl)pyridinamines having memory enhancing activity |
| US4752610A (en) * | 1985-12-04 | 1988-06-21 | Hoechst-Roussel Pharmaceuticals Inc. | N-(pyrrol-1-yl)pyridinamines having memory enhancing properties |
| ATE115143T1 (de) * | 1987-04-24 | 1994-12-15 | Hoechst Roussel Pharma | N-(pyridinyl)-1h-indol-1-amine, verfahren zu deren herstellung und ihre verwendung als arzneimittel. |
| US4806554A (en) * | 1988-01-11 | 1989-02-21 | Hoechst-Roussel Pharmaceuticals, Inc. | Pyrazol and indazolpyridinamines |
| US4916135A (en) * | 1989-05-08 | 1990-04-10 | Hoechst Roussel Pharmaceuticals Inc. | N-heteroaryl-4-quinolinamines |
| ATE118002T1 (de) * | 1989-08-02 | 1995-02-15 | Hoechst Roussel Pharma | 2,3-dihydro-1-(pyridinylamino)-indole, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel. |
| US5006537A (en) * | 1989-08-02 | 1991-04-09 | Hoechst-Roussel Pharmaceuticals, Inc. | 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones |
-
1988
- 1988-12-27 US US07/289,887 patent/US4868190A/en not_active Expired - Lifetime
-
1989
- 1989-12-21 AT AT89123612T patent/ATE79118T1/de not_active IP Right Cessation
- 1989-12-21 IE IE894175A patent/IE894175L/xx unknown
- 1989-12-21 DE DE8989123612T patent/DE68902386T2/de not_active Expired - Fee Related
- 1989-12-21 NZ NZ231943A patent/NZ231943A/en unknown
- 1989-12-21 ES ES89123612T patent/ES2044043T3/es not_active Expired - Lifetime
- 1989-12-21 EP EP89123612A patent/EP0376155B1/en not_active Expired - Lifetime
- 1989-12-22 FI FI896243A patent/FI896243A7/fi not_active Application Discontinuation
- 1989-12-22 NO NO89895222A patent/NO895222L/no unknown
- 1989-12-22 DK DK662189A patent/DK662189A/da not_active Application Discontinuation
- 1989-12-22 CA CA002006529A patent/CA2006529C/en not_active Expired - Fee Related
- 1989-12-22 PT PT92696A patent/PT92696A/pt unknown
- 1989-12-22 AU AU47203/89A patent/AU623205B2/en not_active Ceased
- 1989-12-25 IL IL92867A patent/IL92867A0/xx unknown
- 1989-12-26 JP JP1335256A patent/JPH0725749B2/ja not_active Expired - Fee Related
- 1989-12-26 KR KR1019890019472A patent/KR900009596A/ko not_active Withdrawn
- 1989-12-26 PH PH39801A patent/PH27122A/en unknown
- 1989-12-27 ZA ZA899904A patent/ZA899904B/xx unknown
-
1992
- 1992-11-04 GR GR920402184T patent/GR3006140T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH02247173A (ja) | 1990-10-02 |
| NO895222D0 (no) | 1989-12-22 |
| ZA899904B (en) | 1991-02-27 |
| FI896243A7 (fi) | 1990-06-28 |
| AU4720389A (en) | 1990-07-05 |
| DK662189D0 (da) | 1989-12-22 |
| PH27122A (en) | 1993-03-16 |
| DE68902386T2 (de) | 1993-02-11 |
| KR900009596A (ko) | 1990-07-05 |
| NZ231943A (en) | 1992-06-25 |
| DK662189A (da) | 1990-06-28 |
| CA2006529A1 (en) | 1990-06-27 |
| IE894175L (en) | 1990-06-27 |
| GR3006140T3 (en:Method) | 1993-06-21 |
| NO895222L (no) | 1990-06-28 |
| FI896243A0 (fi) | 1989-12-22 |
| ATE79118T1 (de) | 1992-08-15 |
| JPH0725749B2 (ja) | 1995-03-22 |
| AU623205B2 (en) | 1992-05-07 |
| EP0376155B1 (en) | 1992-08-05 |
| US4868190A (en) | 1989-09-19 |
| CA2006529C (en) | 1999-08-10 |
| PT92696A (pt) | 1990-06-29 |
| IL92867A0 (en) | 1990-09-17 |
| EP0376155A1 (en) | 1990-07-04 |
| DE68902386D1 (de) | 1992-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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