DK662189A - Pyridinylcarbazolaminer, deres fremstilling og anvendelse som laegemidler - Google Patents

Pyridinylcarbazolaminer, deres fremstilling og anvendelse som laegemidler Download PDF

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Publication number
DK662189A
DK662189A DK662189A DK662189A DK662189A DK 662189 A DK662189 A DK 662189A DK 662189 A DK662189 A DK 662189A DK 662189 A DK662189 A DK 662189A DK 662189 A DK662189 A DK 662189A
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DK
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Prior art keywords
loweralkyl
hydrogen
preparation
halogen
carbzolamines
Prior art date
Application number
DK662189A
Other languages
Danish (da)
English (en)
Other versions
DK662189D0 (da
Inventor
Richard Charles Effland
Joseph Thomas Klein
Larry Davis
Gordon Edward Olsen
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK662189D0 publication Critical patent/DK662189D0/da
Publication of DK662189A publication Critical patent/DK662189A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK662189A 1988-12-27 1989-12-22 Pyridinylcarbazolaminer, deres fremstilling og anvendelse som laegemidler DK662189A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/289,887 US4868190A (en) 1988-12-27 1988-12-27 N-pyridinyl-9H-carbazol-9-amines

Publications (2)

Publication Number Publication Date
DK662189D0 DK662189D0 (da) 1989-12-22
DK662189A true DK662189A (da) 1990-06-28

Family

ID=23113557

Family Applications (1)

Application Number Title Priority Date Filing Date
DK662189A DK662189A (da) 1988-12-27 1989-12-22 Pyridinylcarbazolaminer, deres fremstilling og anvendelse som laegemidler

Country Status (19)

Country Link
US (1) US4868190A (en:Method)
EP (1) EP0376155B1 (en:Method)
JP (1) JPH0725749B2 (en:Method)
KR (1) KR900009596A (en:Method)
AT (1) ATE79118T1 (en:Method)
AU (1) AU623205B2 (en:Method)
CA (1) CA2006529C (en:Method)
DE (1) DE68902386T2 (en:Method)
DK (1) DK662189A (en:Method)
ES (1) ES2044043T3 (en:Method)
FI (1) FI896243A7 (en:Method)
GR (1) GR3006140T3 (en:Method)
IE (1) IE894175L (en:Method)
IL (1) IL92867A0 (en:Method)
NO (1) NO895222L (en:Method)
NZ (1) NZ231943A (en:Method)
PH (1) PH27122A (en:Method)
PT (1) PT92696A (en:Method)
ZA (1) ZA899904B (en:Method)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
ATE118002T1 (de) * 1989-08-02 1995-02-15 Hoechst Roussel Pharma 2,3-dihydro-1-(pyridinylamino)-indole, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel.
US5179099A (en) * 1989-08-02 1993-01-12 Hoechst-Roussel Pharmaceuticals Incorporated 2,3-dihydro-1-(pyridinylamino)-indoles
US4994472A (en) * 1989-08-02 1991-02-19 Hoechst-Roussel Pharmaceuticals Incorporated 1-(pyridinylamino)-2-pyrrolidinones as pain relievers
US4983608A (en) * 1989-09-05 1991-01-08 Hoechst-Roussell Pharmaceuticals, Inc. N-substituted-4-pyrimidinamines and pyrimidinediamines
KR100445629B1 (ko) * 1995-07-27 2004-10-14 아벤티스 파마슈티칼스 인크. 비치환및치환된n-(피롤-1-일)피리딘아민의항경련제로서의용도
US5776955A (en) * 1995-07-27 1998-07-07 Hoechst Marion Roussel, Inc. Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents
ZA989365B (en) * 1997-10-15 1999-04-15 Boehringer Mannheim Pharm Corp Preparation for treating alzheimer's disease
EP1305082B1 (en) * 2000-07-21 2004-05-26 Ortho-McNeil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH475982A (de) * 1966-11-16 1969-07-31 Wander Ag Dr A Verfahren zur Herstellung von Carbazolderivaten
EP0073849A1 (en) * 1981-09-03 1983-03-16 Schering Corporation Novel phenyl-1,2,3,4-tetrahydrocarbazoles, their preparation and pharmaceutical compositions containing them
US4792562A (en) * 1985-12-04 1988-12-20 Hoechst-Roussel Pharmaceuticals, Inc. N-(pyrrol-1-yl)pyridinamines having memory enhancing activity
US4752610A (en) * 1985-12-04 1988-06-21 Hoechst-Roussel Pharmaceuticals Inc. N-(pyrrol-1-yl)pyridinamines having memory enhancing properties
ATE115143T1 (de) * 1987-04-24 1994-12-15 Hoechst Roussel Pharma N-(pyridinyl)-1h-indol-1-amine, verfahren zu deren herstellung und ihre verwendung als arzneimittel.
US4806554A (en) * 1988-01-11 1989-02-21 Hoechst-Roussel Pharmaceuticals, Inc. Pyrazol and indazolpyridinamines
US4916135A (en) * 1989-05-08 1990-04-10 Hoechst Roussel Pharmaceuticals Inc. N-heteroaryl-4-quinolinamines
ATE118002T1 (de) * 1989-08-02 1995-02-15 Hoechst Roussel Pharma 2,3-dihydro-1-(pyridinylamino)-indole, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel.
US5006537A (en) * 1989-08-02 1991-04-09 Hoechst-Roussel Pharmaceuticals, Inc. 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones

Also Published As

Publication number Publication date
JPH02247173A (ja) 1990-10-02
NO895222D0 (no) 1989-12-22
ZA899904B (en) 1991-02-27
FI896243A7 (fi) 1990-06-28
AU4720389A (en) 1990-07-05
DK662189D0 (da) 1989-12-22
PH27122A (en) 1993-03-16
DE68902386T2 (de) 1993-02-11
KR900009596A (ko) 1990-07-05
NZ231943A (en) 1992-06-25
CA2006529A1 (en) 1990-06-27
IE894175L (en) 1990-06-27
GR3006140T3 (en:Method) 1993-06-21
NO895222L (no) 1990-06-28
FI896243A0 (fi) 1989-12-22
ES2044043T3 (es) 1994-01-01
ATE79118T1 (de) 1992-08-15
JPH0725749B2 (ja) 1995-03-22
AU623205B2 (en) 1992-05-07
EP0376155B1 (en) 1992-08-05
US4868190A (en) 1989-09-19
CA2006529C (en) 1999-08-10
PT92696A (pt) 1990-06-29
IL92867A0 (en) 1990-09-17
EP0376155A1 (en) 1990-07-04
DE68902386D1 (de) 1992-09-10

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ATS Application withdrawn