ES2043762T3 - Reactivos desnaturalizantes para la determinacion conveniente de derivados de hemoglobina en sangre. - Google Patents
Reactivos desnaturalizantes para la determinacion conveniente de derivados de hemoglobina en sangre.Info
- Publication number
- ES2043762T3 ES2043762T3 ES88118104T ES88118104T ES2043762T3 ES 2043762 T3 ES2043762 T3 ES 2043762T3 ES 88118104 T ES88118104 T ES 88118104T ES 88118104 T ES88118104 T ES 88118104T ES 2043762 T3 ES2043762 T3 ES 2043762T3
- Authority
- ES
- Spain
- Prior art keywords
- hemoglobin
- blood
- derivative
- measured
- denaturalizing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/723—Glycosylated haemoglobin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Nanotechnology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
UN METODO ANCLITICO PARA DETERMINAR LA RELATIVA CANTIDAD DE UN PARTICULAR DERIVADO DE LA EMOGLOBINA, EJEMPLO: EN UNA MUESTRA DE SANGRE DONDE LAS CANTIDADES TOTALES DE HEMOGLOBINA Y DERIVADO DE LA MISMA SON CALCULADOS Y RELACIONADOS MATEMATICAMENTE, EJEM., ASI COMO UN PORCENTAJE, LA MUESTRA DE SANGRE ES TRATADA CON LA CONVICCION DE UNA SAL TIOCENATADA Y UN OXIDENTE PARA DENATURAR LA HEMOGLOBINA EN UNA MUESTRA, Y PARA CONVERTIR HEMOGLOBINA EN LLET-HEMOGLOBINA. ESTA ULTIMA ES CALCULADA ESPECTROMETRICAMENTE PARA DAR LA CANTIDAD DE HEMOGLOBINA TOTAL PRESENTE Y LA HEMOGLOBINA DENATURADA Y DERIVADA PUEDE SER DISTINGUIDA Y CALCULADA POR UN INMUNOENSAYO. LA PRESENCIA DEL OXIDANTE Y LA SOLUCION DENATURANTE HA SIDO ENCONTRADA PARA INCREMENTAR EL TANTO POR CIENTO DE DESNATURALIZACION DE LA HEDMOGLOBINA ASI COMO REDUCIENDO SOBRE TODO EL TIEMPO DE ENSAYO Y AUMENTANDO LA SEGURIDAD DE LA DETERMINACION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/118,476 US4970171A (en) | 1987-11-09 | 1987-11-09 | Denaturant reagents for convenient determination of hemoglobin derivatives in blood |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2043762T3 true ES2043762T3 (es) | 1994-01-01 |
Family
ID=22378843
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88118104T Expired - Lifetime ES2043762T3 (es) | 1987-11-09 | 1988-10-31 | Reactivos desnaturalizantes para la determinacion conveniente de derivados de hemoglobina en sangre. |
Country Status (11)
Country | Link |
---|---|
US (1) | US4970171A (es) |
EP (1) | EP0315864B1 (es) |
JP (1) | JP2683572B2 (es) |
AT (1) | ATE83561T1 (es) |
AU (1) | AU601086B2 (es) |
CA (1) | CA1340220C (es) |
DE (1) | DE3876761T2 (es) |
DK (1) | DK174495B1 (es) |
ES (1) | ES2043762T3 (es) |
IE (1) | IE62086B1 (es) |
IL (1) | IL87682A (es) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5162237A (en) * | 1988-04-11 | 1992-11-10 | Miles Inc. | Reaction cassette for preforming sequential analytical assays by noncentrifugal and noncapillary manipulations |
US5258311A (en) * | 1989-07-13 | 1993-11-02 | Miles Inc. | Lithium salts as red blood cell lysing and hemoglobin denaturing reagents |
IL94724A (en) * | 1989-07-13 | 1994-02-27 | Miles Inc | Decomposition of red blood cells and denaturation of hemoglobin by the use of lithium salts |
US5151369A (en) * | 1989-07-13 | 1992-09-29 | Miles Inc. | Lithium salts as red blood cell lysing and hemoglobin denaturing reagents |
US5183739A (en) * | 1990-02-27 | 1993-02-02 | Exocell, Inc. | Monoclonal antibodies specific for non-a1c glycated hemoglobin and immunoassay methods |
DE4206932A1 (de) * | 1992-03-05 | 1993-09-09 | Boehringer Mannheim Gmbh | Immunologische methode zur bestimmung eines haemoglobinderivates |
WO1994000592A1 (en) * | 1992-06-26 | 1994-01-06 | Exocell, Inc. | Monoclonal antibodies against glycated low density lipoprotein |
US5372948A (en) | 1993-03-17 | 1994-12-13 | Miles Inc. | Assay and reaction vessel with a compartmentalized solubilization chamber |
US6043043A (en) * | 1993-04-02 | 2000-03-28 | Bayer Corporation | Method for the determination of hemoglobin adducts |
US5874229A (en) * | 1995-08-07 | 1999-02-23 | Kyoto Daiichi Kagaku Co., Ltd. | Method for avoiding influence of hemoglobin |
JP3269765B2 (ja) | 1995-12-14 | 2002-04-02 | 富士写真フイルム株式会社 | ヘモグロビン誘導体の免疫学的測定方法及びその方法に用いる処理試薬 |
US5902731A (en) * | 1998-09-28 | 1999-05-11 | Lifescan, Inc. | Diagnostics based on tetrazolium compounds |
AU2001282550A1 (en) * | 2000-09-07 | 2002-03-22 | Wako Pure Chemical Industries, Ltd. | Method of quantifying total hemoglobin and glycohemoglobin |
DE10054055A1 (de) | 2000-10-31 | 2002-05-23 | Nmi Univ Tuebingen | Verfahren zur Analyse von Proteinen |
ATE453668T1 (de) * | 2001-04-26 | 2010-01-15 | Dako Denmark As | Pan-spezifischer monoklonaler antikörper der gegen glycosiliertes hämoglobin gerichtet ist |
US6562581B2 (en) | 2001-08-31 | 2003-05-13 | Portascience | Method for quantitative determination of glycated hemoglobin |
US7459127B2 (en) | 2002-02-26 | 2008-12-02 | Siemens Healthcare Diagnostics Inc. | Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces |
US7618788B2 (en) * | 2002-05-10 | 2009-11-17 | Millipore Corporation | Proteome epitope tags and methods of use thereof in protein modification analysis |
US7460960B2 (en) * | 2002-05-10 | 2008-12-02 | Epitome Biosystems, Inc. | Proteome epitope tags and methods of use thereof in protein modification analysis |
US7094354B2 (en) | 2002-12-19 | 2006-08-22 | Bayer Healthcare Llc | Method and apparatus for separation of particles in a microfluidic device |
US7125711B2 (en) | 2002-12-19 | 2006-10-24 | Bayer Healthcare Llc | Method and apparatus for splitting of specimens into multiple channels of a microfluidic device |
DE10305050A1 (de) * | 2003-02-07 | 2004-08-19 | Roche Diagnostics Gmbh | Analytisches Testelement und Verfahren für Blutuntersuchungen |
US7347617B2 (en) | 2003-08-19 | 2008-03-25 | Siemens Healthcare Diagnostics Inc. | Mixing in microfluidic devices |
US20050227370A1 (en) * | 2004-03-08 | 2005-10-13 | Ramel Urs A | Body fluid analyte meter & cartridge system for performing combined general chemical and specific binding assays |
JP4957547B2 (ja) * | 2005-04-14 | 2012-06-20 | パナソニック株式会社 | ヘモグロビン誘導体の測定方法、それに用いる試薬組成物、測定キット、分析デバイス、及び分析システム |
WO2007077579A1 (en) * | 2006-01-04 | 2007-07-12 | Jawaharlal Nehru University | A novelprocess for detecting human haemoglobin variants |
US7855057B2 (en) * | 2006-03-23 | 2010-12-21 | Millipore Corporation | Protein splice variant/isoform discrimination and quantitative measurements thereof |
WO2008093722A1 (ja) * | 2007-01-30 | 2008-08-07 | Arkray, Inc. | フェノチアジン誘導体色素の検出方法およびそれに用いる発色剤試薬 |
ES2541114T3 (es) * | 2007-11-20 | 2015-07-16 | Siemens Healthcare Diagnostics Inc. | Métodos para la detección de hemoglobina glicosilada |
WO2010067612A1 (ja) | 2008-12-11 | 2010-06-17 | 積水メディカル株式会社 | 糖化ヘモグロビン含有試料の前処理法 |
ES2961300T3 (es) | 2010-03-31 | 2024-03-11 | Sekisui Medical Co Ltd | Método para analizar hemoglobinas |
WO2016054033A1 (en) * | 2014-09-30 | 2016-04-07 | Siemens Healthcare Diagnostics Inc. | Processes, systems, and devices for hemolysis detection via measurement of methemoglobin |
WO2018081161A1 (en) | 2016-10-24 | 2018-05-03 | Biomatrica, Inc. | Stabilization of nucleic acids on paper |
WO2019203302A1 (ja) * | 2018-04-18 | 2019-10-24 | 積水メディカル株式会社 | ヘモグロビン分析方法 |
CN112113955B (zh) * | 2020-09-15 | 2022-03-18 | 四川行之智汇知识产权运营有限公司 | 血红蛋白检测卡 |
CN113866406B (zh) * | 2021-10-18 | 2022-09-27 | 深圳上泰生物工程有限公司 | 一种特异性检测糖缺失性转铁蛋白的试剂盒 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4247533A (en) * | 1978-05-01 | 1981-01-27 | The Rockefeller University | Hemoglobin A1c radioimmunoassay |
US4255385A (en) * | 1979-10-23 | 1981-03-10 | Abbott Laboratories | Reagent and test kit for determining glycosylated hemoglobin |
US4260516A (en) * | 1979-12-07 | 1981-04-07 | Abbott Laboratories | Glycosylated hemoglobin standards |
US4649122A (en) * | 1980-09-02 | 1987-03-10 | Leeco Diagnostics, Inc. | Means for determining percentage of glycohemoglobin in whole blood |
US4407961A (en) * | 1981-03-16 | 1983-10-04 | Sanders James L | Ion-exchange system and method for isolation and determination of glycosylated hemoglobin in human blood |
DE3141146A1 (de) * | 1981-10-16 | 1983-04-28 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und reagens zur bestimmung von glykosiliertem haemoglobin |
US4880749A (en) * | 1984-06-05 | 1989-11-14 | Eastman Kodak Company | Analytical element and its use in a whole blood hemoglobin assay |
US4658022A (en) * | 1985-08-08 | 1987-04-14 | Molecular Diagnostics, Inc. | Binding of antibody reagents to denatured protein analytes |
CA1339952C (en) * | 1984-10-29 | 1998-07-14 | William J. Knowles | Immunoassays for denatured protein analytes, particularly hb alc, and monoclonal antibodies thereto |
US4647654A (en) * | 1984-10-29 | 1987-03-03 | Molecular Diagnostics, Inc. | Peptides useful in preparing hemoglobin A1c immunogens |
DK145385D0 (da) * | 1985-03-29 | 1985-04-01 | Novo Industri As | Monoklonalt antistof til immunkemisk analyse |
US4800167A (en) * | 1987-04-10 | 1989-01-24 | Abbott Laboratories | Reagent and process for the determination of hemoglobin in blood |
-
1987
- 1987-11-09 US US07/118,476 patent/US4970171A/en not_active Expired - Lifetime
-
1988
- 1988-09-06 IL IL87682A patent/IL87682A/xx not_active IP Right Cessation
- 1988-09-08 CA CA000576787A patent/CA1340220C/en not_active Expired - Lifetime
- 1988-10-31 DE DE8888118104T patent/DE3876761T2/de not_active Expired - Lifetime
- 1988-10-31 ES ES88118104T patent/ES2043762T3/es not_active Expired - Lifetime
- 1988-10-31 AT AT88118104T patent/ATE83561T1/de not_active IP Right Cessation
- 1988-10-31 EP EP88118104A patent/EP0315864B1/en not_active Expired - Lifetime
- 1988-11-03 AU AU24655/88A patent/AU601086B2/en not_active Ceased
- 1988-11-08 IE IE335688A patent/IE62086B1/en not_active IP Right Cessation
- 1988-11-08 JP JP63280552A patent/JP2683572B2/ja not_active Expired - Lifetime
- 1988-11-08 DK DK198806227A patent/DK174495B1/da not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IE883356L (en) | 1989-05-09 |
AU2465588A (en) | 1989-05-11 |
DK622788A (da) | 1989-05-10 |
DK622788D0 (da) | 1988-11-08 |
EP0315864A1 (en) | 1989-05-17 |
ATE83561T1 (de) | 1993-01-15 |
JPH01155268A (ja) | 1989-06-19 |
AU601086B2 (en) | 1990-08-30 |
DK174495B1 (da) | 2003-04-22 |
IL87682A (en) | 1992-08-18 |
IL87682A0 (en) | 1989-02-28 |
US4970171A (en) | 1990-11-13 |
CA1340220C (en) | 1998-12-15 |
IE62086B1 (en) | 1994-12-14 |
DE3876761T2 (de) | 1993-04-22 |
EP0315864B1 (en) | 1992-12-16 |
JP2683572B2 (ja) | 1997-12-03 |
DE3876761D1 (de) | 1993-01-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2043762T3 (es) | Reactivos desnaturalizantes para la determinacion conveniente de derivados de hemoglobina en sangre. | |
ATE193378T1 (de) | Immunologische methode zur bestimmung von hbaic | |
CA2096250A1 (en) | Assay for glycated blood proteins | |
ATE249049T1 (de) | Verfahren zur bestimmung des prozentualen anteils von glykosiliertem hämoglobin | |
Leslie et al. | Determination of mercapto groups in proteins with N-ethylmaleimide | |
GR3006991T3 (es) | ||
DE3683532D1 (de) | Bestimmung von glycohaemoglobin (glycosyliertem haemoglobin) in blut. | |
ATE271220T1 (de) | Borathaltige speicherpuffer und probenverdünner | |
AU625137B2 (en) | Lithium salts as red blood cell lysing and hemoglobin denaturing reagents | |
CA2019426A1 (en) | Lithium salts as red blood cells lysing hemoglobin denaturing reagents | |
ES2061537T3 (es) | Reactivo y procedimiento para la determinacion de hemoglobina en la sangre. | |
CA1263590C (en) | CYANIDE-FREE REAGENT FOR THE DETERMINATION OF HEMOGLOBIN | |
EP0175577A3 (en) | Microchemiluminescent assay system | |
ES2028124T3 (es) | Metodo para la determinacion de albumina en fluidos biologicos. | |
DE60003106T2 (de) | Reagenz zur Bestimmung von Leukozyten und zur Messung von Hämoglobin in einer Blutprobe |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 315864 Country of ref document: ES |