ES2042528T3 - Un procedimiento de preparacion de una composicion para potenciar la penetracion por membranas de al menos un agente sistematicamente activo. - Google Patents
Un procedimiento de preparacion de una composicion para potenciar la penetracion por membranas de al menos un agente sistematicamente activo.Info
- Publication number
- ES2042528T3 ES2042528T3 ES87116755T ES87116755T ES2042528T3 ES 2042528 T3 ES2042528 T3 ES 2042528T3 ES 87116755 T ES87116755 T ES 87116755T ES 87116755 T ES87116755 T ES 87116755T ES 2042528 T3 ES2042528 T3 ES 2042528T3
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- membrane penetration
- preparing
- procedure
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M13/00—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment
- D06M13/322—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with compounds containing nitrogen
- D06M13/402—Amides imides, sulfamic acids
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M16/00—Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic
-
- D—TEXTILES; PAPER
- D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
- D06P—DYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
- D06P1/00—General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed
- D06P1/44—General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed using insoluble pigments or auxiliary substances, e.g. binders
- D06P1/64—General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed using insoluble pigments or auxiliary substances, e.g. binders using compositions containing low-molecular-weight organic compounds without sulfate or sulfonate groups
- D06P1/642—Compounds containing nitrogen
- D06P1/649—Compounds containing carbonamide, thiocarbonamide or guanyl groups
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Textile Engineering (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Wood Science & Technology (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LA INVENCION SE REFIERE A UN METODO PARA ADMINISTRAR AGENTES ACTIVOS SISTEMICAMENTE INCLUYENDO AGENTES TERAPEUTICOS, A TRAVES DE LA PIEL O DE LAS MUCOSAS, EN HOMBRES Y ANIMALES EN UN DISPOSITIVO O FORMULACION TRANSDERMICOS QUE CONSISTE EN ADMINISTRAR TOPICAMENTE CON DICHO AGENTE SISTEMICO, UNA CANTIDAD EFECTIVA DE UN MEJORADOR DE LA PENETRACION EN MEMBRANAS, DE FORMULA ESTRUCTURAL (I), EN LA QUE R1 Y R2 SE SELECCIONAN INDEPENDIENTEMENTE DEL GRUPO FORMADO POR RADICALES ALQUILO Y CICLOALQUILO DE 1 A 20 ATOMOS DE C, Y R SE SELECCIONA DEL GRUPO FORMADO POR RADICALES ALQUILO Y CICLOALQUILO DE 1 A 30 C, CON LA CONDICION DE QUE EL NUMERO TOTAL DE ATOMOS DE C EN DICHOS COMPUESTOS SEA 15 O MAYOR Y EL NUMERO TOTAL DE ATOMOS DE C EN R1 Y R2 SEA 5 O MAYOR.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/932,651 US4808414A (en) | 1986-09-29 | 1986-11-19 | Amide penetration enhancers for transdermal delivery of systemic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2042528T3 true ES2042528T3 (es) | 1993-12-16 |
Family
ID=25462662
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES87116755T Expired - Lifetime ES2042528T3 (es) | 1986-11-19 | 1987-11-13 | Un procedimiento de preparacion de una composicion para potenciar la penetracion por membranas de al menos un agente sistematicamente activo. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4808414A (es) |
EP (1) | EP0268220B1 (es) |
JP (1) | JPS63139136A (es) |
KR (1) | KR880005945A (es) |
AT (1) | ATE76303T1 (es) |
AU (1) | AU624573B2 (es) |
DE (1) | DE3779260D1 (es) |
ES (1) | ES2042528T3 (es) |
GR (1) | GR3005442T3 (es) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4973579A (en) * | 1985-06-28 | 1990-11-27 | Merck & Co., Inc. | Enhancment of absorption of drugs from gastrointestinal tract using choline ester salts |
US4902676A (en) * | 1986-09-29 | 1990-02-20 | Nelson Research & Development Co. | Compositions comprising N,N-dialkylalkanamides |
ES2038154T3 (es) * | 1986-11-19 | 1993-07-16 | Whitby Research, Inc. | Un procedimiento para preparar una composicion para potenciar la penetracion de membranas de al menos un agente sistematicamente activo. |
US5234959A (en) * | 1988-04-08 | 1993-08-10 | Whitby Research, Inc. | Penetration enhancers for transdermal delivery of systemic agents |
US5472946A (en) * | 1988-04-08 | 1995-12-05 | Peck; James V. | Transdermal penetration enhancers |
US4927626A (en) * | 1988-10-28 | 1990-05-22 | Devillez Richard L | Method for enhancement of unguis growth |
US5059603A (en) * | 1989-06-12 | 1991-10-22 | Centuries Laboratories, Inc. | Method and composition for treating impotence |
AU6712090A (en) * | 1989-10-13 | 1991-05-16 | Watson Laboratories, Inc. | Drug delivery systems and matrix therefor |
US5518734A (en) * | 1991-09-25 | 1996-05-21 | Beta Pharmaceuticals Co. | Transdermal delivery system for estradiol and process for manufacturing said device |
US5705185A (en) * | 1991-09-25 | 1998-01-06 | Beta Pharmaceuticals Co. | Transdermal delivery of estradiol and process for manufacturing said device |
NZ244862A (en) * | 1991-10-23 | 1995-07-26 | Block Drug Co | Use of vitamin e in topical pharmaceuticals to enhance penetration of the active agent |
JP3202777B2 (ja) * | 1992-01-24 | 2001-08-27 | リンテック株式会社 | 経皮吸収促進剤及びテープ製剤 |
TW224048B (es) * | 1992-03-30 | 1994-05-21 | Hoechst Roussel Pharma | |
EP0746294B1 (en) * | 1993-10-07 | 2004-12-22 | Odontex, Inc. | Absorption enhancers for topical pharmaceutical formulations |
WO1995022351A1 (fr) * | 1994-02-18 | 1995-08-24 | Institute For Advanced Skin Research Inc. | Composition pour application locale |
US6414028B1 (en) | 1997-11-05 | 2002-07-02 | Nexmed Holdings, Inc. | Topical compositions containing prostaglandin E1 |
US6046244A (en) * | 1997-11-05 | 2000-04-04 | Nexmed Holdings, Inc. | Topical compositions for prostaglandin E1 delivery |
US6147102A (en) * | 1999-10-26 | 2000-11-14 | Curatek Pharmaceuticals Holding, Inc. | Clonidine preparations |
DE10041478A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
US6638981B2 (en) * | 2001-08-17 | 2003-10-28 | Epicept Corporation | Topical compositions and methods for treating pain |
US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
ES2239196T3 (es) * | 2002-12-02 | 2005-09-16 | Schwarz Pharma Ag | Suministro iontoforetico de rotigotina para el tratamiento de la enfermedad de parkinson. |
PL1814531T3 (pl) | 2004-10-21 | 2010-11-30 | Durect Corp | Transdermalne systemy dostarczania |
US8252319B2 (en) | 2004-10-21 | 2012-08-28 | Durect Corporation | Transdermal delivery system for sufentanil |
US20060223786A1 (en) * | 2005-04-01 | 2006-10-05 | Smith David J | Transdermal pain control method and device |
US20070248657A1 (en) * | 2006-04-25 | 2007-10-25 | Smith David J | Multi-compartment transdermal pain control device |
EP1987815A1 (en) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders |
AU2009296457A1 (en) | 2008-09-27 | 2010-04-01 | Taraxos Inc. | Topical formulations for treatment of neuropathy |
US20100221313A1 (en) * | 2008-12-01 | 2010-09-02 | Innovative Pharmaceuticals, Llc | Transdermal reservoir patch |
WO2021010843A1 (en) | 2019-07-16 | 2021-01-21 | Donaghys Limited | Transdermal solvent system and methods of use |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3954966A (en) * | 1970-06-08 | 1976-05-04 | Ceskoslovenska Akademie Ved | Infusion solutions and method of manufacturing same |
NL7214924A (es) * | 1971-11-09 | 1973-05-11 | ||
GB1421743A (en) * | 1972-04-18 | 1976-01-21 | Wilkinson Sword Ltd | Ingestible topical and other compositions |
GB1427744A (en) * | 1973-05-11 | 1976-03-10 | Whitlock Inc | Protective wrapping for an elongate member |
DE2947648A1 (de) * | 1979-11-27 | 1981-08-06 | C.F. Spiess & Sohn GmbH & Co, 6719 Kleinkarlbach | Verwendung tertiaerer heterocyclischer amine als potenzierungsmittel fuer insektizide |
DE3009546A1 (de) * | 1980-03-13 | 1981-09-24 | Henkel KGaA, 4000 Düsseldorf | Desodorierende kosmetische zusammensetzungen |
US4590190A (en) * | 1983-07-01 | 1986-05-20 | Nitto Electric Industrial Co., Ltd. | Method for percutaneously administering physiologically active agents using an alcohol adjuvant and a solvent |
US4743588A (en) * | 1984-06-13 | 1988-05-10 | Allergan Pharmaceuticals, Inc. | Compositions and methods of enhancing transdermal and transmembrane penetration systemic agents |
US4680172A (en) * | 1985-03-05 | 1987-07-14 | Ciba-Geigy Corporation | Devices and methods for treating memory impairment |
CH666621A5 (de) * | 1986-06-27 | 1988-08-15 | Ciba Geigy Ag | Topisch applizierbare pharmazeutische zusammensetzungen mit systemischer wirkung. |
US4902676A (en) * | 1986-09-29 | 1990-02-20 | Nelson Research & Development Co. | Compositions comprising N,N-dialkylalkanamides |
-
1986
- 1986-11-19 US US06/932,651 patent/US4808414A/en not_active Expired - Lifetime
-
1987
- 1987-11-13 AT AT87116755T patent/ATE76303T1/de not_active IP Right Cessation
- 1987-11-13 EP EP87116755A patent/EP0268220B1/en not_active Expired - Lifetime
- 1987-11-13 ES ES87116755T patent/ES2042528T3/es not_active Expired - Lifetime
- 1987-11-13 DE DE8787116755T patent/DE3779260D1/de not_active Expired - Fee Related
- 1987-11-18 AU AU81326/87A patent/AU624573B2/en not_active Ceased
- 1987-11-18 KR KR870012976A patent/KR880005945A/ko not_active Application Discontinuation
- 1987-11-19 JP JP62293092A patent/JPS63139136A/ja active Pending
-
1992
- 1992-08-19 GR GR920401763T patent/GR3005442T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3005442T3 (es) | 1993-05-24 |
ATE76303T1 (de) | 1992-06-15 |
EP0268220A2 (en) | 1988-05-25 |
AU624573B2 (en) | 1992-06-18 |
DE3779260D1 (de) | 1992-06-25 |
US4808414A (en) | 1989-02-28 |
EP0268220B1 (en) | 1992-05-20 |
KR880005945A (ko) | 1988-07-21 |
JPS63139136A (ja) | 1988-06-10 |
AU8132687A (en) | 1988-05-26 |
EP0268220A3 (en) | 1988-09-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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