ES8609280A1 - Procedimiento para preparar derivados azolilalquilicos - Google Patents

Procedimiento para preparar derivados azolilalquilicos

Info

Publication number
ES8609280A1
ES8609280A1 ES539717A ES539717A ES8609280A1 ES 8609280 A1 ES8609280 A1 ES 8609280A1 ES 539717 A ES539717 A ES 539717A ES 539717 A ES539717 A ES 539717A ES 8609280 A1 ES8609280 A1 ES 8609280A1
Authority
ES
Spain
Prior art keywords
processes
preparation
azolyl
derivatives
alkanole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES539717A
Other languages
English (en)
Other versions
ES539717A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES8609280A1 publication Critical patent/ES8609280A1/es
Publication of ES539717A0 publication Critical patent/ES539717A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/60—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS AZOLILALQUILICOS. COMPRENDE: A) HACER REACCIONAR UN C.F. (II) CON UN C.F. (III), PARA OBTENER UN C.F. (IV); B) HACER REACCIONAR EL C.F. (IV) CON UN C.F. (V) PARA OBTENER EL C.F. (I); C) OXIDAR EL C.F. (I) CUANDO Q SEA -S-R2, O REDUCIRLO, CUANDO Q SEA RADICAL DE FORMULA (VI), CON UN HIDRURO METALICO COMPLEJO; D) TRANSFORMAR EL C.F. (I) EN QUE R1 ES H, EN UN ALCOHOLATO METALICO, CON UNA BASE FUERTE; Y E) TRATAR EL ALCOHOLATO CON UN C.F. ER1. SIENDO: A, -CHF, O H; AR, FENILO SUSTITUIDO POR HALOGENOS Y/O ALQUILOS, Y OTROS; R1, H, ALQUILO DE C 1 A 12 Y OTROS; E, GRUPO LABIL REACTIVO; ME, H O METAL ALCALINO O ALCALINOTERREO; N, ENTERO DE 2 A 12; Z, 0 O 1; Y C.F., COMPUESTO DE FORMULA. SE UTILIZA COMO ANTIMICOTICO Y ANTIBACTERIANO PARA GRAM B Y C.
ES539717A 1984-01-23 1985-01-21 Procedimiento para preparar derivados azolilalquilicos Expired ES8609280A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3402166A DE3402166A1 (de) 1984-01-23 1984-01-23 Azolyl-aryl-alkanol-derivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
ES8609280A1 true ES8609280A1 (es) 1986-07-16
ES539717A0 ES539717A0 (es) 1986-07-16

Family

ID=6225645

Family Applications (3)

Application Number Title Priority Date Filing Date
ES539717A Expired ES8609280A1 (es) 1984-01-23 1985-01-21 Procedimiento para preparar derivados azolilalquilicos
ES550961A Expired ES8707720A1 (es) 1984-01-23 1986-01-16 Procedimiento para preparar derivados azolilalquilicos
ES550960A Expired ES8707719A1 (es) 1984-01-23 1986-01-16 Procedimiento para preparar derivados azolialquilicos

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES550961A Expired ES8707720A1 (es) 1984-01-23 1986-01-16 Procedimiento para preparar derivados azolilalquilicos
ES550960A Expired ES8707719A1 (es) 1984-01-23 1986-01-16 Procedimiento para preparar derivados azolialquilicos

Country Status (12)

Country Link
EP (1) EP0150036A1 (es)
JP (1) JPS60174771A (es)
KR (1) KR850005416A (es)
AU (1) AU3797485A (es)
DE (1) DE3402166A1 (es)
DK (1) DK28685A (es)
ES (3) ES8609280A1 (es)
FI (1) FI850266L (es)
GR (1) GR850174B (es)
IL (1) IL74133A0 (es)
PT (1) PT79858B (es)
ZA (1) ZA85487B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3702301A1 (de) * 1986-03-06 1987-09-10 Bayer Ag 2-hydroxyethyl-azol-derivate
ATE54312T1 (de) * 1986-03-06 1990-07-15 Bayer Ag 2-hydroxyethyl-azol-derivate.
JPH0717634B2 (ja) * 1987-11-20 1995-03-01 シェリング・コーポレーション トリ‐およびテトラ‐置換‐オキセタンおよびテトラヒドロフランおよびその中間体
AU621076B2 (en) * 1987-12-25 1992-03-05 Sumitomo Pharmaceuticals Company, Limited Process for preparation of sulfone derivatives
US5039691A (en) * 1989-06-08 1991-08-13 Marion Merrell Dow Inc. 5-(1-(imidazol)methyl)-3,3-disubstituted-2(3H)furanone derivatives
JPH05255089A (ja) * 1991-12-18 1993-10-05 Sanwa Kagaku Kenkyusho Co Ltd 抗ウイルス剤
CA2145458A1 (en) * 1994-03-28 1995-09-29 Hiroki Kodama Triazole compound and production process and use thereof
ES2164238T3 (es) 1995-04-06 2002-02-16 Sankyo Co Agente antifungico de triazol.
CN102803231A (zh) * 2009-06-18 2012-11-28 巴斯夫欧洲公司 杀真菌的1，2，4-三唑衍生物
US10071971B2 (en) 2012-12-19 2018-09-11 Basf Se Substituted [1,2,4]triazole compounds and their use as fungicides
US20150329501A1 (en) 2012-12-19 2015-11-19 Basf Se Substituted [1,2,4]triazole compounds and their use as fungicides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2736122A1 (de) * 1977-08-11 1979-02-22 Basf Ag Fungizide
NZ196075A (en) * 1980-02-04 1982-12-07 Janssen Pharmaceutica Nv Agent to protect wood coatings and detergents from micro-organisms using a triazole
CA1162540A (en) * 1980-12-24 1984-02-21 Ikutaro Saji Imidazolylpropanol compounds and their acid addition salts, and production and use thereof
US4435399A (en) * 1981-07-18 1984-03-06 Pfizer Inc. 2-Aryl-1-(imidazol-1-yl)-8-(4-piperazin-1-ylphenoxy) octan-2-ol antifungal agents
US4940481A (en) * 1982-03-04 1990-07-10 Ciba-Geigy Corporation Microbicidal and growth regulating compositions
DK161382C (da) * 1982-04-01 1991-12-09 Pfizer Fremgangsmaade til fremstilling af 1,2,4-triazol-forbindelser eller farmaceutisk acceptable syreadditionssalte deraf
DE3212388A1 (de) * 1982-04-02 1983-10-13 Bayer Ag, 5090 Leverkusen Substituierte hydroxyalkyl-azole, verfahren zu ihrer herstellung und ihre verwendung als antimykotika

Also Published As

Publication number Publication date
PT79858B (en) 1986-11-20
KR850005416A (ko) 1985-08-26
FI850266L (fi) 1985-07-24
ZA85487B (en) 1985-08-28
ES8707719A1 (es) 1987-08-16
DE3402166A1 (de) 1985-07-25
DK28685A (da) 1985-07-24
ES8707720A1 (es) 1987-08-16
ES550960A0 (es) 1987-08-16
GR850174B (es) 1985-05-13
FI850266A0 (fi) 1985-01-21
ES550961A0 (es) 1987-08-16
DK28685D0 (da) 1985-01-22
PT79858A (en) 1985-02-01
IL74133A0 (en) 1985-04-30
JPS60174771A (ja) 1985-09-09
AU3797485A (en) 1985-08-01
EP0150036A1 (de) 1985-07-31
ES539717A0 (es) 1986-07-16

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