ATE76303T1 - Penetrationsverbesserer fuer die transdermale verabreichung von systemisch wirksamen arzneimitteln. - Google Patents

Penetrationsverbesserer fuer die transdermale verabreichung von systemisch wirksamen arzneimitteln.

Info

Publication number
ATE76303T1
ATE76303T1 AT87116755T AT87116755T ATE76303T1 AT E76303 T1 ATE76303 T1 AT E76303T1 AT 87116755 T AT87116755 T AT 87116755T AT 87116755 T AT87116755 T AT 87116755T AT E76303 T1 ATE76303 T1 AT E76303T1
Authority
AT
Austria
Prior art keywords
carbon atoms
transdermal delivery
penetration enhancers
systemic drugs
total number
Prior art date
Application number
AT87116755T
Other languages
English (en)
Inventor
James V Peck
Gevork Nmi Minaskanian
Original Assignee
Whitby Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Whitby Research Inc filed Critical Whitby Research Inc
Application granted granted Critical
Publication of ATE76303T1 publication Critical patent/ATE76303T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
    • D06M13/00—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment
    • D06M13/322—Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with non-macromolecular organic compounds; Such treatment combined with mechanical treatment with compounds containing nitrogen
    • D06M13/402—Amides imides, sulfamic acids
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
    • D06M16/00—Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06P—DYEING OR PRINTING TEXTILES; DYEING LEATHER, FURS OR SOLID MACROMOLECULAR SUBSTANCES IN ANY FORM
    • D06P1/00—General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed
    • D06P1/44—General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed using insoluble pigments or auxiliary substances, e.g. binders
    • D06P1/64—General processes of dyeing or printing textiles, or general processes of dyeing leather, furs, or solid macromolecular substances in any form, classified according to the dyes, pigments, or auxiliary substances employed using insoluble pigments or auxiliary substances, e.g. binders using compositions containing low-molecular-weight organic compounds without sulfate or sulfonate groups
    • D06P1/642—Compounds containing nitrogen
    • D06P1/649—Compounds containing carbonamide, thiocarbonamide or guanyl groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Textile Engineering (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT87116755T 1986-11-19 1987-11-13 Penetrationsverbesserer fuer die transdermale verabreichung von systemisch wirksamen arzneimitteln. ATE76303T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/932,651 US4808414A (en) 1986-09-29 1986-11-19 Amide penetration enhancers for transdermal delivery of systemic agents
EP87116755A EP0268220B1 (de) 1986-11-19 1987-11-13 Penetrationsverbesserer für die transdermale Verabreichung von systemisch wirksamen Arzneimitteln

Publications (1)

Publication Number Publication Date
ATE76303T1 true ATE76303T1 (de) 1992-06-15

Family

ID=25462662

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87116755T ATE76303T1 (de) 1986-11-19 1987-11-13 Penetrationsverbesserer fuer die transdermale verabreichung von systemisch wirksamen arzneimitteln.

Country Status (9)

Country Link
US (1) US4808414A (de)
EP (1) EP0268220B1 (de)
JP (1) JPS63139136A (de)
KR (1) KR880005945A (de)
AT (1) ATE76303T1 (de)
AU (1) AU624573B2 (de)
DE (1) DE3779260D1 (de)
ES (1) ES2042528T3 (de)
GR (1) GR3005442T3 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973579A (en) * 1985-06-28 1990-11-27 Merck & Co., Inc. Enhancment of absorption of drugs from gastrointestinal tract using choline ester salts
US4902676A (en) * 1986-09-29 1990-02-20 Nelson Research & Development Co. Compositions comprising N,N-dialkylalkanamides
DE3778833D1 (de) * 1986-11-19 1992-06-11 Whitby Research Inc Penetrationsverbesserer fuer die transdermale verabreichung von systemisch wirksamen arzneimitteln.
US5472946A (en) * 1988-04-08 1995-12-05 Peck; James V. Transdermal penetration enhancers
US5234959A (en) * 1988-04-08 1993-08-10 Whitby Research, Inc. Penetration enhancers for transdermal delivery of systemic agents
US4927626A (en) * 1988-10-28 1990-05-22 Devillez Richard L Method for enhancement of unguis growth
US5059603A (en) * 1989-06-12 1991-10-22 Centuries Laboratories, Inc. Method and composition for treating impotence
WO1991005529A1 (en) * 1989-10-13 1991-05-02 Watson Laboratories, Inc. Drug delivery systems and matrix therefor
US5518734A (en) * 1991-09-25 1996-05-21 Beta Pharmaceuticals Co. Transdermal delivery system for estradiol and process for manufacturing said device
US5705185A (en) * 1991-09-25 1998-01-06 Beta Pharmaceuticals Co. Transdermal delivery of estradiol and process for manufacturing said device
AU658681B2 (en) * 1991-10-23 1995-04-27 Block Drug Company Inc., The Penetration enhancement of topically applied formulations
JP3202777B2 (ja) * 1992-01-24 2001-08-27 リンテック株式会社 経皮吸収促進剤及びテープ製剤
TW224048B (de) * 1992-03-30 1994-05-21 Hoechst Roussel Pharma
WO1995009590A1 (en) * 1993-10-07 1995-04-13 Odontex, Inc. Absorption enhancers for topical pharmaceutical formulations
US5759528A (en) * 1994-02-18 1998-06-02 Institute For Advanced Skin Research, Inc. Topical composition for promoting transdermal absorption of therapeutic agents
US6414028B1 (en) 1997-11-05 2002-07-02 Nexmed Holdings, Inc. Topical compositions containing prostaglandin E1
US6046244A (en) * 1997-11-05 2000-04-04 Nexmed Holdings, Inc. Topical compositions for prostaglandin E1 delivery
US6147102A (en) * 1999-10-26 2000-11-14 Curatek Pharmaceuticals Holding, Inc. Clonidine preparations
DE10041478A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
US20030026830A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine
US20030027793A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal treatment of parkinson's disease
US6638981B2 (en) * 2001-08-17 2003-10-28 Epicept Corporation Topical compositions and methods for treating pain
US20040048779A1 (en) * 2002-05-06 2004-03-11 Erwin Schollmayer Use of rotigotine for treating the restless leg syndrome
DK1426049T3 (da) * 2002-12-02 2005-08-22 Sanol Arznei Schwarz Gmbh Iontophoretisk tilförsel af rotigotin til behandling af Parkinsons sygdom
US8252319B2 (en) 2004-10-21 2012-08-28 Durect Corporation Transdermal delivery system for sufentanil
DE602005021909D1 (de) 2004-10-21 2010-07-29 Durect Corp Transdermale verabreichungssysteme
US20060223786A1 (en) * 2005-04-01 2006-10-05 Smith David J Transdermal pain control method and device
US20070248657A1 (en) * 2006-04-25 2007-10-25 Smith David J Multi-compartment transdermal pain control device
EP1987815A1 (de) * 2007-05-04 2008-11-05 Schwarz Pharma Ag Im Mund-Nasen-Rachenraum verabreichbare pharmazeutische Zusammensetzungen enthaltend Dopaminagonisten zur Vorbeugung und/oder Behandlung von unruhigen Gliedmassen
WO2010036937A1 (en) 2008-09-27 2010-04-01 Taraxos Inc. Topical formulations for treatment of neuropathy
US20100221313A1 (en) * 2008-12-01 2010-09-02 Innovative Pharmaceuticals, Llc Transdermal reservoir patch
BR112022000767A2 (pt) 2019-07-16 2022-03-15 Donaghys Ltd Sistema de solvente transdérmico e métodos de uso

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3954966A (en) * 1970-06-08 1976-05-04 Ceskoslovenska Akademie Ved Infusion solutions and method of manufacturing same
NL7214924A (de) * 1971-11-09 1973-05-11
GB1421743A (en) * 1972-04-18 1976-01-21 Wilkinson Sword Ltd Ingestible topical and other compositions
GB1427744A (en) * 1973-05-11 1976-03-10 Whitlock Inc Protective wrapping for an elongate member
DE2947648A1 (de) * 1979-11-27 1981-08-06 C.F. Spiess & Sohn GmbH & Co, 6719 Kleinkarlbach Verwendung tertiaerer heterocyclischer amine als potenzierungsmittel fuer insektizide
DE3009546A1 (de) * 1980-03-13 1981-09-24 Henkel KGaA, 4000 Düsseldorf Desodorierende kosmetische zusammensetzungen
US4590190A (en) * 1983-07-01 1986-05-20 Nitto Electric Industrial Co., Ltd. Method for percutaneously administering physiologically active agents using an alcohol adjuvant and a solvent
US4743588A (en) * 1984-06-13 1988-05-10 Allergan Pharmaceuticals, Inc. Compositions and methods of enhancing transdermal and transmembrane penetration systemic agents
US4680172A (en) * 1985-03-05 1987-07-14 Ciba-Geigy Corporation Devices and methods for treating memory impairment
CH666621A5 (de) * 1986-06-27 1988-08-15 Ciba Geigy Ag Topisch applizierbare pharmazeutische zusammensetzungen mit systemischer wirkung.
US4902676A (en) * 1986-09-29 1990-02-20 Nelson Research & Development Co. Compositions comprising N,N-dialkylalkanamides

Also Published As

Publication number Publication date
GR3005442T3 (de) 1993-05-24
JPS63139136A (ja) 1988-06-10
EP0268220B1 (de) 1992-05-20
DE3779260D1 (de) 1992-06-25
EP0268220A2 (de) 1988-05-25
KR880005945A (ko) 1988-07-21
ES2042528T3 (es) 1993-12-16
US4808414A (en) 1989-02-28
AU8132687A (en) 1988-05-26
AU624573B2 (en) 1992-06-18
EP0268220A3 (en) 1988-09-21

Similar Documents

Publication Publication Date Title
ATE76303T1 (de) Penetrationsverbesserer fuer die transdermale verabreichung von systemisch wirksamen arzneimitteln.
AU568590B2 (en) Penetration enhancers for transdermal drug delivery of systemic agents
EP0164998A3 (de) Mittel und Verfahren zur Erhöhung der transdermalen und transmembranen Penetration topischer und systemischer Wirkstoffe
DE3751761D1 (de) Penetrationsverbesserer für die transdermale Verabreichung von systemisch wirksamen Arzneimitteln
EP0172228A4 (de) Substrat zum verabreichen aktiver arzneimittel auf menschliche haut.
DE3688075D1 (de) Transdermales verabreichungssystem.
MY100947A (en) External pharmaceutical composition.
ATE162725T1 (de) Verbesserte hautpenetrationssysteme fuer erhoehte topische freisetzung von arzneimitteln
DK0674513T3 (da) Retroviral protease-inhiberende forbindelser
ATE131041T1 (de) Galenische zusammensetzung für die topische anwendung.
ATE63220T1 (de) Transdermal resorbierbare, wasserhaltige zubereitungen von arylpropionsaeurederivaten und verfahren zur herstellung derselben.
ATE210966T1 (de) Reduzierung von durch liposome induzierte physiologischen gegenreaktionen
ES2054962T3 (es) Agentes plaguicidas.
ES2148158T3 (es) Uso de adipato de dibutilo y miristato de isopropilo en productos topicos y transdermicos.
ATE75620T1 (de) Penetrationsverbesserer fuer die transdermale verabreichung von systemisch wirksamen arzneimitteln.
SE8101374L (sv) Kompositioner innehallande n,n-dietyl-m-toluamid
ES2005042A6 (es) Procedimiento de preparar derivados de aminoacidos que tienen actividad sobre el sistema nervioso central.
KR900701278A (ko) 바이러스 감염 치료용 담즙산
KR930016417A (ko) 피롤릴벤조디아제핀온
EP0335446A3 (de) Mittel zur Behandlung von Neoplasmen
KR880005929A (ko) 전신 약품의 경피 투여용 침투 증강제
KR920019349A (ko) 불안을 치료하기 위한 r(+)-3-아미노-1-하이드록시-피롤리딘-2-온의 용도
BG48452A3 (en) Insecticide composition
UA26326C2 (uk) Спосіб лікуваhhя захворюваhь вірусhої та бактеріальhої етіології у людиhи і твариhи та композиція для його реалізації

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee