ATE75620T1 - Penetrationsverbesserer fuer die transdermale verabreichung von systemisch wirksamen arzneimitteln. - Google Patents
Penetrationsverbesserer fuer die transdermale verabreichung von systemisch wirksamen arzneimitteln.Info
- Publication number
- ATE75620T1 ATE75620T1 AT87116753T AT87116753T ATE75620T1 AT E75620 T1 ATE75620 T1 AT E75620T1 AT 87116753 T AT87116753 T AT 87116753T AT 87116753 T AT87116753 T AT 87116753T AT E75620 T1 ATE75620 T1 AT E75620T1
- Authority
- AT
- Austria
- Prior art keywords
- sulfur
- transdermal delivery
- penetration enhancers
- represent oxygen
- chem
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 230000009885 systemic effect Effects 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003623 enhancer Substances 0.000 title 1
- 230000035515 penetration Effects 0.000 title 1
- 230000037317 transdermal delivery Effects 0.000 title 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 4
- 229910052760 oxygen Inorganic materials 0.000 abstract 4
- 239000001301 oxygen Substances 0.000 abstract 4
- 229910052717 sulfur Inorganic materials 0.000 abstract 4
- 239000011593 sulfur Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003961 penetration enhancing agent Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93270886A | 1986-11-19 | 1986-11-19 | |
| EP87116753A EP0268218B1 (de) | 1986-11-19 | 1987-11-13 | Penetrationsverbesserer für die transdermale Verabreichung von systemisch wirksamen Arzneimitteln |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE75620T1 true ATE75620T1 (de) | 1992-05-15 |
Family
ID=25462769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87116753T ATE75620T1 (de) | 1986-11-19 | 1987-11-13 | Penetrationsverbesserer fuer die transdermale verabreichung von systemisch wirksamen arzneimitteln. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0268218B1 (de) |
| JP (1) | JPS63150230A (de) |
| KR (1) | KR880005946A (de) |
| AT (1) | ATE75620T1 (de) |
| AU (1) | AU607951B2 (de) |
| DE (1) | DE3778833D1 (de) |
| ES (1) | ES2038154T3 (de) |
| GR (1) | GR3005138T3 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1319613C (en) * | 1986-10-07 | 1993-06-29 | Gevork Minaskanian | Penetration enhancers for transdermal delivery of systemic agents |
| US5518734A (en) * | 1991-09-25 | 1996-05-21 | Beta Pharmaceuticals Co. | Transdermal delivery system for estradiol and process for manufacturing said device |
| US5705185A (en) * | 1991-09-25 | 1998-01-06 | Beta Pharmaceuticals Co. | Transdermal delivery of estradiol and process for manufacturing said device |
| EP0552504B1 (de) * | 1992-01-20 | 1998-04-29 | Schwarz Pharma Ag | 1-Oleoylazacycloheptanon(2) enthaltende Arzneimittel zur Verstärkung des Transports durch biologische Membranen |
| ES2133710T3 (es) * | 1993-11-25 | 1999-09-16 | Warwick Int Group | Composiciones blanqueantes. |
| US6147102A (en) * | 1999-10-26 | 2000-11-14 | Curatek Pharmaceuticals Holding, Inc. | Clonidine preparations |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL246488A (de) * | 1959-12-02 | |||
| FR2152456B1 (de) * | 1971-09-16 | 1974-10-18 | Morelle Jean | |
| SU528848A1 (ru) * | 1975-03-12 | 1977-11-05 | Филиал Всесоюзного Научно-Исследовательского Химико-Фармацевтического Института Имени С.Орджоникидзе | , -(Дитиооксалил)-бис- бутиролактам, про вл ющий антимикробную активность, и способ его получени |
| GB1553310A (en) * | 1975-06-19 | 1979-09-26 | Nelson Res & Dev | Vehicle composition containing 1-substituted azacycloalkan-2-ones |
| US4557934A (en) * | 1983-06-21 | 1985-12-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one |
| US4743588A (en) * | 1984-06-13 | 1988-05-10 | Allergan Pharmaceuticals, Inc. | Compositions and methods of enhancing transdermal and transmembrane penetration systemic agents |
| ES8605233A1 (es) * | 1985-12-06 | 1986-03-16 | Lazlo Int Sa | Procedimiento de obtencion de imidas derivadas de la 2-oxo- pirrolidina |
| EP0257086B1 (de) * | 1986-01-31 | 1993-01-20 | WHITBY RESEARCH, Inc. | Hautpenetration verbessernde Zusammensetzungen |
| US4808414A (en) * | 1986-09-29 | 1989-02-28 | Nelson Research & Development Co. | Amide penetration enhancers for transdermal delivery of systemic agents |
| ZA871586B (en) * | 1987-03-05 | 1987-10-28 | Aromac Proprietary Limited | Fly-trap |
-
1987
- 1987-11-13 AT AT87116753T patent/ATE75620T1/de not_active IP Right Cessation
- 1987-11-13 EP EP87116753A patent/EP0268218B1/de not_active Expired - Lifetime
- 1987-11-13 DE DE8787116753T patent/DE3778833D1/de not_active Expired - Fee Related
- 1987-11-13 ES ES198787116753T patent/ES2038154T3/es not_active Expired - Lifetime
- 1987-11-18 KR KR870012977A patent/KR880005946A/ko not_active Ceased
- 1987-11-18 AU AU81325/87A patent/AU607951B2/en not_active Ceased
- 1987-11-19 JP JP62293090A patent/JPS63150230A/ja active Pending
-
1992
- 1992-07-10 GR GR920401475T patent/GR3005138T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0268218A3 (en) | 1988-09-14 |
| GR3005138T3 (de) | 1993-05-24 |
| JPS63150230A (ja) | 1988-06-22 |
| ES2038154T3 (es) | 1993-07-16 |
| KR880005946A (ko) | 1988-07-21 |
| EP0268218B1 (de) | 1992-05-06 |
| AU8132587A (en) | 1988-05-26 |
| DE3778833D1 (de) | 1992-06-11 |
| EP0268218A2 (de) | 1988-05-25 |
| AU607951B2 (en) | 1991-03-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |