ES2040783T3 - Procedimiento para preparar antagonistas de leucotrienos. - Google Patents
Procedimiento para preparar antagonistas de leucotrienos.Info
- Publication number
- ES2040783T3 ES2040783T3 ES198888111746T ES88111746T ES2040783T3 ES 2040783 T3 ES2040783 T3 ES 2040783T3 ES 198888111746 T ES198888111746 T ES 198888111746T ES 88111746 T ES88111746 T ES 88111746T ES 2040783 T3 ES2040783 T3 ES 2040783T3
- Authority
- ES
- Spain
- Prior art keywords
- leukotrene
- antagonists
- preparing
- procedure
- combinations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873724735 DE3724735A1 (de) | 1987-07-25 | 1987-07-25 | Leukotrienantagonisten, verfahren zu ihrer herstellung, ihre anwendung zur behandlung von krankheiten, sowie vorprodukte |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2040783T3 true ES2040783T3 (es) | 1993-11-01 |
Family
ID=6332390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198888111746T Expired - Lifetime ES2040783T3 (es) | 1987-07-25 | 1988-07-21 | Procedimiento para preparar antagonistas de leucotrienos. |
Country Status (16)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5286895A (en) * | 1992-02-19 | 1994-02-15 | Merck & Co., Inc. | Cholesterol lowering compounds |
| KR100411191B1 (ko) * | 1996-06-12 | 2004-03-30 | 한솔제지주식회사 | 재활용이 용이한 방습지 |
| EP2711352A4 (en) * | 2011-05-19 | 2015-02-18 | Ube Industries | POLYVALENTIC AROMATIC VINYL COMPOUND AND METHOD FOR THE PRODUCTION THEREOF |
| WO2019213499A1 (en) * | 2018-05-04 | 2019-11-07 | Saint Louis University | Compounds and methods targeting gper for treatment of diseases associated with calcium |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3894080A (en) * | 1970-05-05 | 1975-07-08 | Rorer Inc William H | Phenylacetic acids |
| US3867434A (en) * | 1971-11-04 | 1975-02-18 | Rorer Inc William H | Phenyl butyric acids and derivatives thereof |
| AT336589B (de) * | 1974-05-20 | 1977-05-10 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen biphenylderivaten |
| US4513005A (en) * | 1981-06-18 | 1985-04-23 | Lilly Industries Limited | SRS-A antagonists |
| US4785004A (en) * | 1985-12-23 | 1988-11-15 | Ciba-Geigy Corporation | Aromatic thioethers |
| GB2190377A (en) * | 1986-05-14 | 1987-11-18 | Merck Frosst Canada Inc | Phenyldithiaalkanedioic acids as leukotriene antagonists |
-
1987
- 1987-07-25 DE DE19873724735 patent/DE3724735A1/de not_active Withdrawn
-
1988
- 1988-07-21 FI FI883455A patent/FI883455A7/fi not_active Application Discontinuation
- 1988-07-21 DE DE8888111746T patent/DE3866460D1/de not_active Expired - Fee Related
- 1988-07-21 AT AT88111746T patent/ATE69809T1/de not_active IP Right Cessation
- 1988-07-21 ES ES198888111746T patent/ES2040783T3/es not_active Expired - Lifetime
- 1988-07-21 EP EP88111746A patent/EP0301401B1/de not_active Expired - Lifetime
- 1988-07-22 US US07/222,975 patent/US4851440A/en not_active Expired - Fee Related
- 1988-07-22 AU AU19296/88A patent/AU610201B2/en not_active Ceased
- 1988-07-22 NO NO883286A patent/NO167799C/no unknown
- 1988-07-22 IL IL87197A patent/IL87197A0/xx unknown
- 1988-07-22 DK DK412388A patent/DK412388A/da not_active Application Discontinuation
- 1988-07-22 ZA ZA885335A patent/ZA885335B/xx unknown
- 1988-07-22 PT PT88074A patent/PT88074B/pt not_active IP Right Cessation
- 1988-07-22 JP JP63181945A patent/JPS6447759A/ja active Pending
- 1988-07-22 NZ NZ225518A patent/NZ225518A/xx unknown
- 1988-07-23 KR KR1019880009266A patent/KR890001974A/ko not_active Withdrawn
-
1992
- 1992-01-08 GR GR910402037T patent/GR3003525T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ225518A (en) | 1990-08-28 |
| DE3866460D1 (de) | 1992-01-09 |
| NO883286D0 (no) | 1988-07-22 |
| GR3003525T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-03-16 |
| ZA885335B (en) | 1989-03-29 |
| NO167799C (no) | 1991-12-11 |
| IL87197A0 (en) | 1988-12-30 |
| AU610201B2 (en) | 1991-05-16 |
| NO883286L (no) | 1989-01-26 |
| DE3724735A1 (de) | 1989-02-02 |
| PT88074B (pt) | 1995-03-01 |
| PT88074A (pt) | 1989-06-30 |
| KR890001974A (ko) | 1989-04-07 |
| NO167799B (no) | 1991-09-02 |
| US4851440A (en) | 1989-07-25 |
| DK412388D0 (da) | 1988-07-22 |
| ATE69809T1 (de) | 1991-12-15 |
| EP0301401A3 (en) | 1989-05-10 |
| FI883455A7 (fi) | 1989-01-26 |
| FI883455A0 (fi) | 1988-07-21 |
| JPS6447759A (en) | 1989-02-22 |
| AU1929688A (en) | 1989-01-27 |
| DK412388A (da) | 1989-01-26 |
| EP0301401A2 (de) | 1989-02-01 |
| EP0301401B1 (de) | 1991-11-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2053451T3 (es) | Un procedimiento para la preparacion de un compuesto que tiene propiedades farmacologicas utiles. | |
| ES2082755T3 (es) | Derivados de acido 3-desmetil-mevalonico, procedimiento para su preparacion, preparados farmaceuticos a base de estos compuestos, su utilizacion asi como productos intermedios. | |
| ES467828A1 (es) | Un procedimiento para preparar nuevos compuestos de cefem y cefam | |
| ES2033400T3 (es) | Procedimiento para producir preparados farmaceuticos estables. | |
| ES2054860T5 (es) | Derivados de 9-halogeno-(z)-prostaglandinas, procedimiento para su preparacion y su utilizacion como medicamentos. | |
| SE8602723L (sv) | Tiazoler, deras framstellning och farmaceutiska kompositioner innehallande dem | |
| ES2055860T3 (es) | Derivados 2-aminopirimidinona. | |
| ES2058061T3 (es) | Derivado de piperidina, su preparacion y su uso como medicamento. | |
| ES2111092T3 (es) | Derivados de acidos biliares, procedimiento para su preparacion y utilizacion de estos compuestos como medicamentos. | |
| ATE84032T1 (de) | Benzimidazolderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate. | |
| IT8747630A0 (it) | Derivati di dicloroanilina, composizioni farmaceutiche che li contengono e procedimento per produrli | |
| ES2129485T3 (es) | Derivados de acidos guanidinoalquil-1,1-bisfosfonicos, procedimiento para su preparacion y su utilizacion. | |
| ES2037013T3 (es) | Procedimiento para preparar tieno-1,4-diazepinas. | |
| ES2009723T3 (es) | Derivados de acidos biliares, procedimientos para la preparacion de los mismos y composiciones farmaceuticas conteniendolos. | |
| MX10059A (es) | Procedimiento para la preparacion de antagonistas de leucotrienos novedosos y producto obtenido | |
| MX9205123A (es) | Derivados de 5-hidroxi-2-pirimidinilmetileno utiles como agentes anti-inflamatorios. | |
| DK561089A (da) | Anvendelse af lactamimider til fremstilling af laegemidler | |
| ES2054738T3 (es) | Derivados de acido 3-desmetil-4-fluoromevalonico, procedimiento para su preparacion, preparados farmaceuticos a base de estos compuestos, su empleo y productos intermedios. | |
| MX9303572A (es) | Inhibidores de proteasa del sindrome de inmunodeficiencia humana, procedimiento para su preparacion y formualcion farmaceutica que los contiene. | |
| ES2040783T3 (es) | Procedimiento para preparar antagonistas de leucotrienos. | |
| ES2127263T3 (es) | Nuevos trien-derivados cromenicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
| ES2032317T3 (es) | Derivados de quinazolina tetraciclicos, obtencion y empleo. | |
| ES2043943T3 (es) | Procedimiento para la preparacion de compuestos con actividad analgesica central. | |
| ES534859A0 (es) | Procedimiento para la obtencion de derivados de 1-(4'-alquilsulfonilfenil)-2-amino-1,3-propandiol n-substituidos | |
| ES2062997T3 (es) | Vinilcefalosporinas sustituidas, procedimiento para su fabricacion y su uso como medicamento. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 301401 Country of ref document: ES |