ES2039408T3 - Un procedimiento para preparar un compuesto de tienotriazolodiazepina. - Google Patents

Un procedimiento para preparar un compuesto de tienotriazolodiazepina.

Info

Publication number
ES2039408T3
ES2039408T3 ES198787116880T ES87116880T ES2039408T3 ES 2039408 T3 ES2039408 T3 ES 2039408T3 ES 198787116880 T ES198787116880 T ES 198787116880T ES 87116880 T ES87116880 T ES 87116880T ES 2039408 T3 ES2039408 T3 ES 2039408T3
Authority
ES
Spain
Prior art keywords
compound
tienotriazolodiazepine
preparing
procedure
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787116880T
Other languages
English (en)
Inventor
Tetsuya Tahara
Minoru Moriwaki
Masao Abe
Shunji Yuasa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Application granted granted Critical
Publication of ES2039408T3 publication Critical patent/ES2039408T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

LA INVENCION SE REFIERE A UN COMPUESTO DE TIENOTRIAZOLDIAZEPINA DE FORMULA GENERAL (I): EN LA QUE CADA UNO DE LOS RADICALES VIENE DEFINIDO, Y UNA SAL DE ADICION DE ACIDOFARMACEUTICAMENTE ACEPTABLE, ASI COMO LAS APLICACIONES FARMACEUTICAS DE DICHOS COMPUESTOS. LOS COMPUESTOS DE LA INVENCION PRESENTAN ACTIVIDAD ANTAGONISTA DE FAP Y SON UTILES PARA LA PREVENCION O TRATAMIENTO DE VARIAS ENFERMEDADES INDUCIDAS POR FAP.
ES198787116880T 1986-11-17 1987-11-16 Un procedimiento para preparar un compuesto de tienotriazolodiazepina. Expired - Lifetime ES2039408T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP27339586 1986-11-17
JP9405887 1987-04-15
JP22272187 1987-09-04

Publications (1)

Publication Number Publication Date
ES2039408T3 true ES2039408T3 (es) 1993-10-01

Family

ID=27307466

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787116880T Expired - Lifetime ES2039408T3 (es) 1986-11-17 1987-11-16 Un procedimiento para preparar un compuesto de tienotriazolodiazepina.

Country Status (4)

Country Link
US (1) US4820703A (es)
EP (1) EP0268242B1 (es)
DE (1) DE3777541D1 (es)
ES (1) ES2039408T3 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
US4959361A (en) * 1987-12-18 1990-09-25 Hoffmann-La Roche Inc. Triazolo(4,3-A)(1,4)benzodiazepines and thieno (3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine compounds which have useful activity as platelet activating factor (PAF) antagonists
CA1322367C (en) * 1988-05-17 1993-09-21 Yoshitomi Pharmaceutical Industries Ltd. Thienotriazolodiazepine compounds and pharmaceutical uses thereof
IL91386A0 (en) * 1988-08-24 1990-04-29 Boehringer Ingelheim Kg Method for treating autoimmune diseases by using a paf antagonist and pharmaceutical compositions comprising it
FI95708C (fi) * 1988-10-31 1996-03-11 Eisai Co Ltd Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
RU2117670C1 (ru) * 1988-10-31 1998-08-20 Эйсай Ко., Лтд. Производные триазоло[1,4]диазепина и способы их получения
EP0387613A1 (de) * 1989-03-03 1990-09-19 Boehringer Ingelheim Kg Neue Thienodiazepine
CA2027076A1 (en) * 1989-10-10 1991-04-11 Werner Stransky Process for preparation of 4-(4-isobutylphenyl)-butyr-aldehyde and its use for the preparation of (-)-4(2-chlorophenyl)-2[2-(4-isobutylphenyl)-ethyl]-6,9-dim ethyl-6h-thieno[3,2-f]1,2,4]-triazolo[4,3][1,4]diazepine
US6277846B1 (en) 1990-05-31 2001-08-21 Allergan Sales, Inc. Use of platelet activating factor antagonists as anti-pruritic agents
JP2959598B2 (ja) * 1990-10-12 1999-10-06 吉富製薬株式会社 光学活性なチエノトリアゾロジアゼピン化合物
US5686479A (en) * 1991-12-11 1997-11-11 Yoshitomi Pharmaceutical Industries, Ltd. Immunosuppressive drug
TW219935B (es) * 1991-12-25 1994-02-01 Mitsubishi Chemicals Co Ltd
US5302590A (en) * 1992-12-18 1994-04-12 Hoffmann-La Roche Inc. Compounds useful as dual antagonists of platelet activating factor and leukotriene D4

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904641A (en) * 1971-06-18 1975-09-09 Yoshitomi Pharmaceutical Triazolothienodiazepine compounds
US4155913A (en) * 1973-02-08 1979-05-22 Hoffmann-La Roche Inc. Thienotriazolodiazepine derivatives
AT338799B (de) * 1974-03-02 1977-09-12 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze
US4201712A (en) * 1975-07-16 1980-05-06 Boehringer Ingelheim Gmbh Process for preparation of 6-aryl-4H-s-triazolo-[3,4-c]-thieno-[2,3-e]-1,4-diazepines
DE3502392A1 (de) * 1985-01-25 1986-07-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen

Also Published As

Publication number Publication date
EP0268242B1 (en) 1992-03-18
DE3777541D1 (de) 1992-04-23
US4820703A (en) 1989-04-11
EP0268242A1 (en) 1988-05-25

Similar Documents

Publication Publication Date Title
ES2072323T3 (es) Compuestos de piperidina y su preparacion y empleo.
EA199900494A1 (ru) Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
EA200001223A1 (ru) Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
EA200001224A1 (ru) Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
EA200000759A1 (ru) Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
ES2039408T3 (es) Un procedimiento para preparar un compuesto de tienotriazolodiazepina.
BR9916282A (pt) Composto, uso de um um composto e método de tratamento
EA200000723A1 (ru) Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
ES2181725T3 (es) Inhibidores de hiv proteasa.
HUT35659A (en) Process for producing 4-amino-methylene-chromane- and-chromene-derivatives and pharmaceutical compositions containing them as active agents
SE8702907D0 (sv) Stable pharmaceutical preparation containing granulocyte colony stimulating factor and process for producing the same
PT88930A (pt) Processo para a preparacao de novos analogos de nucleosidos e de composicoes farmaceuticas que os contem
UA19171A (uk) Спосіб одержаhhя фіhілалкіламіhів або їх фармакологічhо прийhятhих солей
ES2040208T3 (es) Pirazolinas insecticidas.
ES2084339T3 (es) Tetrahidropiridinas e hidroxipiperidinas sustituidas utiles como agentes para el sistema nervioso central.
UA45942A (uk) 1,3-оксатіолан, його похідні, спосіб (варіанти) його одержання та фармацевтична композиція
ATE65402T1 (de) Ifosfamid-mesna-lyophilisat und verfahren zu dessen herstellung.
NO870397D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive organiske platinakomplekser.
DK102892D0 (da) Purin-derivater, farmaceutisk praeparat omfattende forbindelserne samt forbindelser til brug som mellemprodukter
DK707988A (da) Fremgangsmaade til at haemme virus
KR880001596A (ko) 디하이드로피리딘 화합물-함유 뇌기능이상 치료제
DK0505400T3 (da) N-substituerede naphthalimider, deres fremstilling og anvendelse
ES2036545T3 (es) Derivados de n-1h-tetrazol-5-il-(anillo de 5 eslabones)-carboxamida, un procedimiento para su preparacion y el uso de los mismos.
FR2766487B1 (fr) Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
DE3778642D1 (de) Therapeutikum zur behandlung von magengeschwueren.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 268242

Country of ref document: ES