KR880001596A - 디하이드로피리딘 화합물-함유 뇌기능이상 치료제 - Google Patents
디하이드로피리딘 화합물-함유 뇌기능이상 치료제 Download PDFInfo
- Publication number
- KR880001596A KR880001596A KR1019870006847A KR870006847A KR880001596A KR 880001596 A KR880001596 A KR 880001596A KR 1019870006847 A KR1019870006847 A KR 1019870006847A KR 870006847 A KR870006847 A KR 870006847A KR 880001596 A KR880001596 A KR 880001596A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- nitrophenyl
- brain dysfunction
- dihydropyridine
- dihydropyridine compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (4)
- 일반식(I)의 디하이드로피리딘 화합물 또는 그들의 약학적으로 유용한 염을 함유하는 뇌기능이상 치료제.상기식에서 R1은 니트로페닐이고 : R2, R3및 R4는 각각 저급알킬이다.
- 제1항에 있어서, 디하이드로 피리딘 화합물이 6-시아노-5-메톡시카보닐-2-메틸-4-(3-니트로페닐)-1,4-디하이드로피리딘-3-카복실 산인 뇌기능이상 치료제.
- 일반식(I)의 화합물 또는 그들의 약학적으로 유용한 염을 사람을 포함하는 포유동물에 투여함을 특징으로 하여, 이들의 뇌기능 이상을 치료하는 방법.상기식에서 R1은 니트로페닐이고 : R2, R3및 R4는 각각 저급알킬이다.
- 사람을 포함하는포유동물의 뇌기능 이상을 치료하기 위한 일반식(I)의 화합물 또는 그들의 약학적으로 유용한 염의 용도.상기식에서 R1은 니트로페닐이고 : R2, R3및 R4는 각각 저급알킬이다.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP61-154739 | 1986-07-01 | ||
JP15473986 | 1986-07-01 | ||
JP154739? | 1986-07-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR880001596A true KR880001596A (ko) | 1988-04-25 |
KR950009093B1 KR950009093B1 (ko) | 1995-08-14 |
Family
ID=15590865
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019870006847A KR950009093B1 (ko) | 1986-07-01 | 1987-07-01 | 디하이드로피리딘 화합물을 포함하는 뇌기능이상 치료제 |
Country Status (5)
Country | Link |
---|---|
US (1) | US4782070A (ko) |
EP (1) | EP0253173B1 (ko) |
JP (1) | JPS63146861A (ko) |
KR (1) | KR950009093B1 (ko) |
DE (1) | DE3778985D1 (ko) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100380834B1 (ko) * | 1998-06-25 | 2003-04-18 | 엔이씨 일렉트로닉스 코포레이션 | 스위칭 커패시터형 d/a 변환기 및 디스플레이 구동회로 |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0323604B1 (en) * | 1987-12-29 | 1994-05-11 | Fujisawa Pharmaceutical Co., Ltd. | A venous extensibility improving and cardiac hypertrophy suppressant agent containing a dihydropyridine compound |
US5002935A (en) * | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
US5017566A (en) * | 1987-12-30 | 1991-05-21 | University Of Florida | Redox systems for brain-targeted drug delivery |
DE68906942T3 (de) * | 1988-03-29 | 1999-05-12 | Univ Florida | Pharmazeutische Zusammensetzungen für die parenterale Anwendung. |
US5258186A (en) * | 1989-03-10 | 1993-11-02 | Yamanouchi Pharmaceutical Co., Ltd. | Drug release controlling coating material for long acting formulations |
US5258393A (en) * | 1990-02-21 | 1993-11-02 | Fujisawa Pharmaceutical Co., Ltd. | Use of a dihydropyridine compound for improving inner ear microcirculation |
RU1804845C (ru) * | 1991-02-15 | 1993-03-30 | Институт Органического Синтеза Латвийской Ан | Ноотропное вещество |
US20070082792A1 (en) * | 2005-10-12 | 2007-04-12 | Gebelein Paul G | Method and apparatus for passively exercising abdominal muscles |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3307422A1 (de) * | 1983-03-03 | 1984-09-06 | Bayer Ag, 5090 Leverkusen | Fluessigzubereitungen von dihydropyridinen, ein verfahren zu ihrer herstellung, sowie ihre verwendung bei der bekaempfung von erkrankungen |
GB8431119D0 (en) * | 1984-12-10 | 1985-01-16 | Fujisawa Pharmaceutical Co | Anti-arteriosclerotic composition |
-
1987
- 1987-06-19 US US07/063,911 patent/US4782070A/en not_active Expired - Lifetime
- 1987-06-26 EP EP87109187A patent/EP0253173B1/en not_active Expired - Lifetime
- 1987-06-26 DE DE8787109187T patent/DE3778985D1/de not_active Expired - Fee Related
- 1987-06-29 JP JP62161648A patent/JPS63146861A/ja active Granted
- 1987-07-01 KR KR1019870006847A patent/KR950009093B1/ko not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100380834B1 (ko) * | 1998-06-25 | 2003-04-18 | 엔이씨 일렉트로닉스 코포레이션 | 스위칭 커패시터형 d/a 변환기 및 디스플레이 구동회로 |
Also Published As
Publication number | Publication date |
---|---|
KR950009093B1 (ko) | 1995-08-14 |
JPS63146861A (ja) | 1988-06-18 |
US4782070A (en) | 1988-11-01 |
EP0253173A3 (en) | 1989-07-26 |
DE3778985D1 (de) | 1992-06-17 |
EP0253173B1 (en) | 1992-05-13 |
EP0253173A2 (en) | 1988-01-20 |
JPH0546326B2 (ko) | 1993-07-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP9600448A2 (hu) | Naftilvegyületek, e vegyületeket tartalmazó gyógyszerkészítmények, eljárás előállításukra, intermedierjeik és alkalmazásuk | |
ATE83659T1 (de) | Verwendung von indolon-derivaten zur herstellung von arzneimitteln zur behandlung des parkinsonismus. | |
KR880006193A (ko) | 피페리딘 화합물 및 그의 제조 및 용도 | |
KR940005274A (ko) | 쇼그렌(Sjoegren)증후군 치료제 | |
KR890011596A (ko) | 불면증 치료용 의약품의 제조에 있어서 1,4-이치환-피페리디닐 화합물의 용도 | |
KR890003691A (ko) | 피페리딘 유도체 및 그를 함유하는 부정맥을 위한 치료예방제 | |
DE68923151D1 (de) | Verwendung von Trifluormethylphenyl-Tetrahydropyridinen zur Herstellung von Arzneimitteln zur Behandlung anxio-depressiver Erkrankungen. | |
KR880010770A (ko) | 테트라하이드로벤즈[c,d]인돌-6-카복스아미드를 사용한 불안증 치료 방법 | |
KR880001596A (ko) | 디하이드로피리딘 화합물-함유 뇌기능이상 치료제 | |
RU94019425A (ru) | Производные изатиноксима, способ их получения, фармацевтическая композиция и способ лечения | |
FR2585572B3 (fr) | Nouvelles compositions pharmaceutiques a base d'un sel de l'acide p. chlorophenoxyacetique destinees au traitement des neuropathies et assurant la regeneration nerveuse | |
HUT34186A (en) | Process for producing new 1,4-dihydropyridines substituted with chromone and thio-chromone,and pharmaceutical comositions containing them | |
EA200000693A1 (ru) | Антагонисты хемокинного рецептора и способы их применения | |
DE68900516D1 (de) | Therapeutische mittel zur behandlung von magengeschwueren. | |
KR890012942A (ko) | 5-치환된 오르니틴 유도체 | |
KR880004810A (ko) | 소화성 궤양 치료제 | |
EP0228314A3 (en) | Use of ethanol/amine derivatives in treating or preventing hyperlipemia | |
KR910015301A (ko) | 수면 무호흡증의 치료방법 | |
KR880009656A (ko) | 국소 치근막 질환의 치료 또는 예방법 | |
BR9708922A (pt) | Piridil-e pirimidil-piperazinas no tratamento de doenças causadas por substâncias usadas em excesso | |
KR900701273A (ko) | 진토성 에르골린 유도체 | |
KR870001144A (ko) | Nn-디메틸에틸옥사이드가 함유된 약제조성물 및 그의 생산방법 | |
KR890009397A (ko) | 디하이드로피리딘 화합물을 함유하는 뇌뉴우론 보호제 | |
KR880009644A (ko) | 궤양성 대장질환 치료용 약한 조성물 | |
KR910011258A (ko) | 녹내장의 치료방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
G160 | Decision to publish patent application | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20030807 Year of fee payment: 9 |
|
LAPS | Lapse due to unpaid annual fee |