ES2038675T3 - Un procedimiento para preparar compuestos peptidicos. - Google Patents

Un procedimiento para preparar compuestos peptidicos.

Info

Publication number
ES2038675T3
ES2038675T3 ES198787309806T ES87309806T ES2038675T3 ES 2038675 T3 ES2038675 T3 ES 2038675T3 ES 198787309806 T ES198787309806 T ES 198787309806T ES 87309806 T ES87309806 T ES 87309806T ES 2038675 T3 ES2038675 T3 ES 2038675T3
Authority
ES
Spain
Prior art keywords
represent
independently represent
procedure
integers
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787309806T
Other languages
English (en)
Inventor
Ole Didrik Laerum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
Nycomed AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed AS filed Critical Nycomed AS
Application granted granted Critical
Publication of ES2038675T3 publication Critical patent/ES2038675T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C07K7/067—Hemoregulatory peptides based on sequence Glp-Glu-Asp-Cys-Lys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

SE DESCRIBEN NUEVOS COMPUESTOS PEPTIDOS QUE CONSTAN DE CADENAS PEPTIDICAS DIMERAS UNIDAS POR UN PUENTE DISULFURO. TIENEN LA ESTRUCTURA SIGUIENTE:(I) EN LA QUE TODAS LAS UNIDADES DE AMINOACIDOS ESTAN EN LA CONFIGURACION L, A REPRESENTA:(II) O UN ATOMO DE HIDROGENO, B REPRESENTA: (III) O UN ATOMO DE HDROGENO, N Y M INDEPENDIENTEMENTE REPRESENTAN 0 O 1. R, R'' Y R" INDEPENDIENTEMENTE REPRESENTAN UN GRUPO HIDROXI O UN GRUPO AMINO; SUS SALES FISIOLOGICAMENTE COMPATIBLES; CON LA CONDICION DE QUE CUANDO A Y B REPRESNTAN UN ATOMO DE HIDROGENO Y UN GRUPO HIDROXI RESPECTIVAMENTE, B NO PUEDE REPRESENTAR 0. LOS DIMEROS TIENEN UN EFECTO ESTIMULANTE SOBRE LA HEMOPOIESIS, EN CONTRASTE CON EL EFECTO INHIBIDOR DE LOS MONOMEROS ANALOGOS.
ES198787309806T 1986-11-06 1987-11-05 Un procedimiento para preparar compuestos peptidicos. Expired - Lifetime ES2038675T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868626539A GB8626539D0 (en) 1986-11-06 1986-11-06 Peptide compounds

Publications (1)

Publication Number Publication Date
ES2038675T3 true ES2038675T3 (es) 1993-08-01

Family

ID=10606897

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787309806T Expired - Lifetime ES2038675T3 (es) 1986-11-06 1987-11-05 Un procedimiento para preparar compuestos peptidicos.

Country Status (15)

Country Link
US (1) US4987122A (es)
EP (2) EP0267741B1 (es)
JP (1) JP2599947B2 (es)
AT (1) ATE77628T1 (es)
AU (1) AU604279B2 (es)
CA (1) CA1337407C (es)
DE (1) DE3780000T2 (es)
ES (1) ES2038675T3 (es)
FI (1) FI92209C (es)
GB (1) GB8626539D0 (es)
GR (1) GR3005557T3 (es)
IE (1) IE59342B1 (es)
NZ (1) NZ222466A (es)
WO (1) WO1988003535A1 (es)
ZA (1) ZA878349B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO884054D0 (no) * 1988-09-13 1988-09-13 Bio Tech As Nytt pentapeptid og fremgangsmaate for fremstilling derav.
GB8821785D0 (en) * 1988-09-16 1988-10-19 Nycomed As Peptide compounds
ZW11290A1 (en) * 1989-07-14 1990-10-31 Smithkline Beecham Corp Hemoregulatory peptides
HU206372B (en) * 1990-09-03 1992-10-28 Richter Gedeon Vegyeszet Process for producing new oligopeptides which selectively inhibit proliferation of haemopoietic cells and pharmaceutical compositions comprising same
DK53191D0 (da) * 1991-03-25 1991-03-25 Carlbiotech Ltd As Organosvovlforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
IL104323A0 (en) * 1992-01-10 1993-05-13 Smithkline Beecham Corp Hemoregulatory peptides
JPH08501066A (ja) * 1992-06-02 1996-02-06 ハフスルンド・ニユコメド・アクシエセルカペト ペプチド化合物
GB9211677D0 (en) * 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
GB9211668D0 (en) 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
GB9211674D0 (en) 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
US6764693B1 (en) 1992-12-11 2004-07-20 Amaox, Ltd. Free radical quenching composition and a method to increase intracellular and/or extracellular antioxidants
ES2210255T3 (es) * 1993-06-08 2004-07-01 Smithkline Beecham Corporation Metodos para mejorar la actividad biologica de quimiocinas.
GB9314200D0 (en) * 1993-07-09 1993-08-18 Hafslund Nycomed As Peptide compounds
JPH09504301A (ja) * 1993-10-29 1997-04-28 スミスクライン・ビーチャム・コーポレイション 血液調節ペプチド
GB9324691D0 (en) * 1993-12-01 1994-01-19 Hafslund Nycomed As Peptide compounds
WO1997018210A1 (en) * 1995-11-13 1997-05-22 Smithkline Beecham Corporation Hemoregulatory compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI77875C (fi) * 1982-11-26 1989-05-10 Nyegaard & Co As Foerfarande foer framstaellning av nya terapeutiskt anvaendbara peptider.

Also Published As

Publication number Publication date
US4987122A (en) 1991-01-22
DE3780000T2 (de) 1993-02-04
JP2599947B2 (ja) 1997-04-16
IE872983L (en) 1988-05-06
AU8174787A (en) 1988-06-01
GB8626539D0 (en) 1986-12-10
NZ222466A (en) 1990-09-26
FI92209B (fi) 1994-06-30
EP0267741A1 (en) 1988-05-18
FI92209C (fi) 1994-10-10
ZA878349B (en) 1988-05-03
ATE77628T1 (de) 1992-07-15
WO1988003535A1 (en) 1988-05-19
EP0330667A1 (en) 1989-09-06
EP0267741B1 (en) 1992-06-24
FI892185A (fi) 1989-05-05
FI892185A0 (fi) 1989-05-05
GR3005557T3 (es) 1993-06-07
JPH02500517A (ja) 1990-02-22
CA1337407C (en) 1995-10-24
IE59342B1 (en) 1994-02-09
AU604279B2 (en) 1990-12-13
DE3780000D1 (de) 1992-07-30

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