ES2034413T3 - Procedimiento para la obtencion de piperraznina n,n'-disubstituida. - Google Patents
Procedimiento para la obtencion de piperraznina n,n'-disubstituida.Info
- Publication number
- ES2034413T3 ES2034413T3 ES198989101520T ES89101520T ES2034413T3 ES 2034413 T3 ES2034413 T3 ES 2034413T3 ES 198989101520 T ES198989101520 T ES 198989101520T ES 89101520 T ES89101520 T ES 89101520T ES 2034413 T3 ES2034413 T3 ES 2034413T3
- Authority
- ES
- Spain
- Prior art keywords
- sulfur
- alkyl
- oxygen
- heterocycloalkylmethyl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/60—1,4-Diazines; Hydrogenated 1,4-diazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PIPERACINAS N,N''- DISUSTITUIDAS DE FORMULA GENERAL I, EN LA QUE EL GRUPO - ES NO SATURADO (-) O SATURADO (-) Y LOS SUTITUYENTES R1, R2 Y A TIENEN LA SIGNIFICACION SIGUIENTE: A ES -, - CH -, - CH2 -, - CH2 CH2 -; R1 ES ALQUILO, ALQUENILO, ALQUINILO, CICLOALQUILO, CICLOALQUENILO, ALQUIL-CICLOALQUILO, CICLOALQUENIL - ALQUILO, ALQUILO - CICLOALQUENILO, BICICLOALQUILO, BICICLOALQUILALQUILO, ALQUIL BICICLOALQUILO, PUDIENDO ESTAR ESTOS RESTOS SUSTITUIDOS POR HIDROXI, HALOGENO, ALCOXI O TRIALQUILSILILO; R1 PUED SER ADEMAS HETEROCICLOALQUILO CON OXIGENO Y/O AZUFRE, HETEROCICLOALQUILMETILO CON OXIGENO Y/O AZUFRE, ALQUIL - SUSTITUIDO HETEROCICLOALQUILMETILO CON OXIGENO Y/O AZUFRE; R2 ES ALQUILO, ALCOXI, TRIMETILSILIL, CICLOALQUILO O ALQUILTIO. LA INVENCION AFECTA TAMBIEN A LAS SALES COMPATIBLES FITOFISIOLOGICAMENTE DE ESTOS COMPUESTOS Y A LOS FUNGICIDAS QUE CONTIENEN ESTOS COMPUESTOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3803860A DE3803860A1 (de) | 1988-02-09 | 1988-02-09 | N,n'-disubstituierte piperazine |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2034413T3 true ES2034413T3 (es) | 1993-04-01 |
Family
ID=6346955
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198989101520T Expired - Lifetime ES2034413T3 (es) | 1988-02-09 | 1989-01-30 | Procedimiento para la obtencion de piperraznina n,n'-disubstituida. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4935426A (es) |
EP (1) | EP0327912B1 (es) |
JP (1) | JPH0228171A (es) |
AT (1) | ATE74599T1 (es) |
DE (2) | DE3803860A1 (es) |
ES (1) | ES2034413T3 (es) |
GR (1) | GR3005059T3 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1320724C (en) * | 1985-07-19 | 1993-07-27 | Koichi Kanehira | Terpene amino alcohols and medicinal uses thereof |
USH2007H1 (en) * | 1996-01-19 | 2001-12-04 | Fmc Corporation | Insecticidal N-heterocyclylalkyl-or N-[(polycyclyl)alkyl]-N′substituted piperazines |
BR0307429A (pt) * | 2002-02-05 | 2004-12-28 | Novo Nordisk As | Composto, uso do mesmo, composição farmacêutica, e, método para o tratamento de distúrbios ou doenças relacionadas com receptor de histamina h3 |
US20030236259A1 (en) * | 2002-02-05 | 2003-12-25 | Rolf Hohlweg | Novel aryl- and heteroarylpiperazines |
EP2386554A1 (en) | 2005-07-04 | 2011-11-16 | High Point Pharmaceuticals, LLC | Compounds active at the histamine H3 receptor |
CA2653062A1 (en) | 2006-05-23 | 2007-11-29 | Transtech Pharma, Inc. | 6- (4-cyclopropylpiperazin-1-yl) -2 ' -methyl- [3, 4 ' ] -bipyridine and its use as a medicament |
ATE538116T1 (de) | 2006-05-29 | 2012-01-15 | High Point Pharmaceuticals Llc | 3-(1,3-benyodioxol-5-yl)-6- (4- cyclopropylpiperazin-1-yl)-pyridazin, dessen salze und solvate und dessen verwendung als histamin-h3-rezeptorantagonist |
EP2014656A3 (en) | 2007-06-11 | 2011-08-24 | High Point Pharmaceuticals, LLC | New heteocyclic h3 antagonists |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1108226B (de) * | 1956-10-22 | 1961-06-08 | Parke Davis & Co | Verfahren zur Herstellung von hypotensiv wirkenden Phenylpiperazinen |
US2927924A (en) * | 1958-04-03 | 1960-03-08 | Lilly Co Eli | Novel phenethyl-substituted piperazines |
GB998509A (en) * | 1960-11-11 | 1965-07-14 | Chinoin Gyogyszer Es Vegyeszet | A process for the preparation of 1,4-disubstituted piperazine derivatives |
AT227269B (de) * | 1961-03-16 | 1963-05-10 | Henri Morren | Verfahren zur Herstellung neuer Piperazine |
DE2263211A1 (de) * | 1972-12-23 | 1974-07-04 | Boehringer Sohn Ingelheim | Neue arylpiperazine und verfahren zu ihrer herstellung |
DE2727482A1 (de) * | 1977-06-18 | 1979-01-11 | Basf Ag | Derivate cyclischer amine |
US4523014A (en) * | 1983-01-17 | 1985-06-11 | Usv Pharmaceutical Corporation | Piperazines 1-hexyl-4(3-ketohexyl) |
-
1988
- 1988-02-09 DE DE3803860A patent/DE3803860A1/de not_active Withdrawn
-
1989
- 1989-01-30 AT AT89101520T patent/ATE74599T1/de active
- 1989-01-30 DE DE8989101520T patent/DE58901104D1/de not_active Expired - Lifetime
- 1989-01-30 ES ES198989101520T patent/ES2034413T3/es not_active Expired - Lifetime
- 1989-01-30 EP EP89101520A patent/EP0327912B1/de not_active Expired - Lifetime
- 1989-02-08 JP JP1027760A patent/JPH0228171A/ja active Pending
- 1989-02-08 US US07/307,525 patent/US4935426A/en not_active Expired - Fee Related
-
1992
- 1992-06-30 GR GR920401391T patent/GR3005059T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0327912B1 (de) | 1992-04-08 |
US4935426A (en) | 1990-06-19 |
GR3005059T3 (es) | 1993-05-24 |
JPH0228171A (ja) | 1990-01-30 |
DE3803860A1 (de) | 1989-08-17 |
ATE74599T1 (de) | 1992-04-15 |
EP0327912A1 (de) | 1989-08-16 |
DE58901104D1 (de) | 1992-05-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE8804586L (sv) | 1,4-dihydro-4-oxonaftyridinderivat och salter daerav foerfarande foer framstaellning av dessa jaemte antibakteriella medel innefattande dessa | |
BR8800473A (pt) | Processos para preparacao de compostos,e composicoes | |
ES2034413T3 (es) | Procedimiento para la obtencion de piperraznina n,n'-disubstituida. | |
HUT54350A (en) | Insecticidal and nematocidal plant protective compositions, process for producing veterinary compositions suitable for killing helminths and protozoa, as well as process for producing 1-arylimidazoles used as active ingredient | |
ES2059903T3 (es) | Procedimiento para la lucha contra las pestes con ayuda de pirimidinas. | |
ATE2432T1 (de) | Maytansinoide, ihre herstellung und sie enthaltende therapeutischen zusammensetzungen. | |
SE9001269D0 (sv) | 2-substituted n,n-ditrimethoxybenzoyl piperazines,a preparation process of the same and therapeutic compositions containing them | |
SE8005120L (sv) | Acylkarbamider och sett att framstella dess samt insekticida medel, innehallande dessa foreningar | |
HUT43930A (en) | Fungicides comprising naphthimidazolone derivatives as active substance and process for preparing the active substance | |
DE59003191D1 (de) | Oxiran-phenylester und diese enthaltende Fungizide. | |
ATE70050T1 (de) | 1-benzoyl-2-oxo-5-alkoxy-pyrrolidin-derivate, ihre herstellung und verwendung als heilmittel und zubereitungen, die sie enthalten. | |
SE8503054D0 (sv) | Catecholcarboxamides | |
DE3374124D1 (de) | 5-phenylethenylbenzimidazoles | |
JPS5692863A (en) | Novel aminopropanol derivative* its manufacture and heart disease remedy containing it | |
SE8701524L (sv) | Nya sulfonamider och deras framstaellningsfoerfarande | |
JPS56104889A (en) | Nnmethyllnnsilyllcarbamate* its manufacture and and noxious insect repellant containing it | |
ATE98232T1 (de) | 0-(1,2,4-triazolyl-1)-0-phenyl-acetale und diese enthaltende fungizide. | |
ATE189813T1 (de) | Prostaglandin-i-analoga | |
GR3005867T3 (es) | ||
AU8292787A (en) | Fluorine-containing macrolide compounds and their use | |
IL78748A0 (en) | Phosphorimidates,their preparation and their use as pesticides | |
GB2005263A (en) | 8-substituted-3-(1H-tetrazol-5- yl)-4H-1-benzopyran-4-one |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 327912 Country of ref document: ES |