ES2033242T3 - Compuestos organicos y su uso farmaceutico. - Google Patents

Compuestos organicos y su uso farmaceutico.

Info

Publication number
ES2033242T3
ES2033242T3 ES198686309402T ES86309402T ES2033242T3 ES 2033242 T3 ES2033242 T3 ES 2033242T3 ES 198686309402 T ES198686309402 T ES 198686309402T ES 86309402 T ES86309402 T ES 86309402T ES 2033242 T3 ES2033242 T3 ES 2033242T3
Authority
ES
Spain
Prior art keywords
sub
sup
alkyl
hydrogen
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198686309402T
Other languages
English (en)
Inventor
Stephen Richard Baker
Alec Todd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Application granted granted Critical
Publication of ES2033242T3 publication Critical patent/ES2033242T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A COMPUESTOS FARMACEUTICOS DE FORMULA (I): EN LA QUE N ES 0, 1 O 2; R1 ES UN GRUPO HIDROCARBILO QUE CONTIENE DE 6 A 30 ATOIMOS DE C, Y PUEDE ESTAR SUSTITUIDO CON UN GRUPO FENILO QUE PUEDE A SU VEZ ESTAR SUSTITUIDO; R2 ES TETRAZOLILO OPCIONALMENTE PROTEGIDO, O BIEN -COR6 O -NR7 PARA DIFERENTES OPCIONES DE R6 Y R7; Y R3, R4 Y R5 SE SELECCIONAN CADA UNO DE HIDROGENO CARBOXILO, ALCOXICARBONILO DE 2 A 5 C, ALQUILO O ALCOXI DE 1 A 4 C, HIDROXILO, TETRAZOLILO OPCIONALMENTE PROTEGIDO, HALOGENO, TRIFLUORMETILO, NITRILO, NITRO Y -CONR11 2 SIENDO R11 HIDROGENO O ALQUILO DE 1 A 4 C. TAMBIEN SE REFIERE LA INVENCION A LAS SALES DE LOS INDICADOS COMPUESTOS.
ES198686309402T 1985-12-07 1986-12-03 Compuestos organicos y su uso farmaceutico. Expired - Lifetime ES2033242T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858530222A GB8530222D0 (en) 1985-12-07 1985-12-07 Organic compounds

Publications (1)

Publication Number Publication Date
ES2033242T3 true ES2033242T3 (es) 1993-03-16

Family

ID=10589419

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198686309402T Expired - Lifetime ES2033242T3 (es) 1985-12-07 1986-12-03 Compuestos organicos y su uso farmaceutico.

Country Status (8)

Country Link
US (1) US4845110A (es)
EP (1) EP0235452B1 (es)
JP (1) JPS62187445A (es)
AT (1) ATE73781T1 (es)
DE (1) DE3684457D1 (es)
ES (1) ES2033242T3 (es)
GB (2) GB8530222D0 (es)
GR (1) GR3004104T3 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143931A (en) * 1982-06-24 1992-09-01 Smithkline Beecham Corporation Leukotriene antagonists containing tetrazolyl groups
US4939279A (en) * 1985-04-19 1990-07-03 Smithkline Beecham Corporation Leukotriene antagonists
DE3604050A1 (de) * 1986-02-08 1987-08-13 Boehringer Mannheim Gmbh Thioether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
PT87616B (pt) * 1987-06-24 1992-09-30 Smithkline Beecham Corp Processo de preparacao de antagonistas do leucotrieno e de composicoes farmaceuticas
GB8725260D0 (en) * 1987-10-28 1987-12-02 Lilly Industries Ltd Organic compounds
GB8807016D0 (en) * 1988-03-24 1988-04-27 Lilly Industries Ltd Organic compounds & their pharmaceutical use
US5221760A (en) * 1988-05-13 1993-06-22 Bayer Aktiengesellschaft Alkenoic acid derivatives
GB2218416A (en) * 1988-05-13 1989-11-15 Bayer Ag Leukotriene disease antagonists
US4954513A (en) * 1988-12-23 1990-09-04 Smithkline Beecham Corporation Leukotriene antagonists
GB9100493D0 (en) * 1991-01-10 1991-02-20 Bayer Ag Substituted alkenoic acid and its derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8320943D0 (en) * 1983-08-03 1983-09-07 Lilly Industries Ltd Organic compounds
GB8432144D0 (en) * 1984-12-20 1985-01-30 Lilly Industries Ltd Organic compounds
GB8502258D0 (en) * 1985-01-30 1985-02-27 Lilly Industries Ltd Organic compounds

Also Published As

Publication number Publication date
GB8530222D0 (en) 1986-01-15
GB8628960D0 (en) 1987-01-07
EP0235452A2 (en) 1987-09-09
EP0235452A3 (en) 1988-10-26
US4845110A (en) 1989-07-04
EP0235452B1 (en) 1992-03-18
GB2184121A (en) 1987-06-17
ATE73781T1 (de) 1992-04-15
GB2184121B (en) 1990-04-11
JPS62187445A (ja) 1987-08-15
DE3684457D1 (de) 1992-04-23
GR3004104T3 (es) 1993-03-31

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