ES2026824A6 - Procedimiento de obtencion de eritromicina 9-(0-(2-metoxietoxi)metil)oxima). - Google Patents

Procedimiento de obtencion de eritromicina 9-(0-(2-metoxietoxi)metil)oxima).

Info

Publication number
ES2026824A6
ES2026824A6 ES9100777A ES9100777A ES2026824A6 ES 2026824 A6 ES2026824 A6 ES 2026824A6 ES 9100777 A ES9100777 A ES 9100777A ES 9100777 A ES9100777 A ES 9100777A ES 2026824 A6 ES2026824 A6 ES 2026824A6
Authority
ES
Spain
Prior art keywords
erythromycin
oxime
methoxyethoxy
methyl
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9100777A
Other languages
English (en)
Inventor
Cruz Alba Agustin
Vilarelle Eduardo Elias
Marti Antonio Ginebra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prodesfarma SA
Original Assignee
Prodesfarma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prodesfarma SA filed Critical Prodesfarma SA
Priority to ES9100777A priority Critical patent/ES2026824A6/es
Publication of ES2026824A6 publication Critical patent/ES2026824A6/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE ERITROMICINA 9-[O-[(2-METOXI]METIL] OXIMA (ROXITROMICINA), EN EL QUE LA REACCION ENTRE ERITROMICINA 9-OXIMA Y UN COMPUESTO DE FORMULA CHSI3-O-CHSI2CHSI2-O-CHSI2-X*C (X ES UN GRUPO SALIENTE FRENTE A LA SUSTITUCION NUCLEOFILA), SE REALIZA AGITANDO A TEMPERATURA AMBIENTE UNA DISOLUCION DE AMBOS COMPUESTOS EN UN DISOLVENTE ORGANICO INMISCIBLE EN AGUA CON UNA DISOLUCION ACUOSA DE HIDOXIDO SODICO O POTASICO, EN PRESENCIA DE UN CATALIZADOR DE TRANSFERENCIA DE FASE. LA ROXITROMICINA ES UN MACROLIDO RELACIONADO CON LA ERITROMICINA, QUE MUESTRA ACTIVIDAD ANTIBIOTICA FRENTE A BACTERIAS GRAM POSITIVAS, ASI COMO TAMBIEN FRENTE A OTROS GERMENES.
ES9100777A 1991-03-26 1991-03-26 Procedimiento de obtencion de eritromicina 9-(0-(2-metoxietoxi)metil)oxima). Expired - Fee Related ES2026824A6 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9100777A ES2026824A6 (es) 1991-03-26 1991-03-26 Procedimiento de obtencion de eritromicina 9-(0-(2-metoxietoxi)metil)oxima).

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9100777A ES2026824A6 (es) 1991-03-26 1991-03-26 Procedimiento de obtencion de eritromicina 9-(0-(2-metoxietoxi)metil)oxima).

Publications (1)

Publication Number Publication Date
ES2026824A6 true ES2026824A6 (es) 1992-05-01

Family

ID=8271820

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9100777A Expired - Fee Related ES2026824A6 (es) 1991-03-26 1991-03-26 Procedimiento de obtencion de eritromicina 9-(0-(2-metoxietoxi)metil)oxima).

Country Status (1)

Country Link
ES (1) ES2026824A6 (es)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204368B1 (en) 1998-09-10 2001-03-20 Hovione Inter Ltd. Process for the purification of roxithromycin
ES2181546A1 (es) * 1999-07-30 2003-02-16 Biochemie Sa Una eritromicina de oxima y un procedimiento para su obtencion.
EP1435359A1 (en) * 2002-12-31 2004-07-07 Alembic Limited A process for the purification of roxithromycin
CN102887850A (zh) * 2011-07-18 2013-01-23 海洋王照明科技股份有限公司 含吡咯烷离子液体、其制备方法和应用

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204368B1 (en) 1998-09-10 2001-03-20 Hovione Inter Ltd. Process for the purification of roxithromycin
ES2181546A1 (es) * 1999-07-30 2003-02-16 Biochemie Sa Una eritromicina de oxima y un procedimiento para su obtencion.
EP1435359A1 (en) * 2002-12-31 2004-07-07 Alembic Limited A process for the purification of roxithromycin
CN102887850A (zh) * 2011-07-18 2013-01-23 海洋王照明科技股份有限公司 含吡咯烷离子液体、其制备方法和应用

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201