ES2024371A6 - Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima). - Google Patents

Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima).

Info

Publication number
ES2024371A6
ES2024371A6 ES9100302A ES9100302A ES2024371A6 ES 2024371 A6 ES2024371 A6 ES 2024371A6 ES 9100302 A ES9100302 A ES 9100302A ES 9100302 A ES9100302 A ES 9100302A ES 2024371 A6 ES2024371 A6 ES 2024371A6
Authority
ES
Spain
Prior art keywords
erythromycin
oxime
methyl
roxitromycin
methoxyethoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9100302A
Other languages
English (en)
Inventor
Cruz Alba Agusti
Vilarelle Eduardo Elias
Marti Antonio Ginebreda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prodesfarma SA
Original Assignee
Prodesfarma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prodesfarma SA filed Critical Prodesfarma SA
Priority to ES9100302A priority Critical patent/ES2024371A6/es
Publication of ES2024371A6 publication Critical patent/ES2024371A6/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE ERITROMICINA 9-[O-[(2-METOXI]METIL] OXIMA (ROXITROMICINA), EN EL QUE LA REACCION ENTRE ERITROMICINA 9-OXIMA Y UN COMPUESTO DE FORMULA CHSI3-O-CHSI2CHSI2-O-CHSI2-X*C *C (X) ES UN GRUPO SALIENTE FRENTE A LA SUSTITUCION NUCLEOFILA), SE REALIZA AGITANDO A TEMPERATURA AMBIENTE UNA DISOLUCION DE AMBOS COMPUESTOS EN UN DISOLVENTE ORGANICO INMISCIBLE EN AGUA CON UNA DISOLUCION ACUOSA DE HIDROXIDO SODICO O POTASICO, EN PRESENCIA DE UN CATALIZADOR DE TRANSFERENCIA DE FASE. LA ROXITROMICINA ES UN MACROLIDO RELACIONADO CON LA ERITROMICINA, QUE MUESTRA ACTIVIDAD ANTIBIOTICA FRENTE A BACTERIAS GRAM POSITIVAS, ASI COMO TAMBIEN FRENTE A OTROS GERMENES.
ES9100302A 1991-02-06 1991-02-06 Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima). Expired - Fee Related ES2024371A6 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9100302A ES2024371A6 (es) 1991-02-06 1991-02-06 Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima).

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9100302A ES2024371A6 (es) 1991-02-06 1991-02-06 Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima).

Publications (1)

Publication Number Publication Date
ES2024371A6 true ES2024371A6 (es) 1992-02-16

Family

ID=8271092

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9100302A Expired - Fee Related ES2024371A6 (es) 1991-02-06 1991-02-06 Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima).

Country Status (1)

Country Link
ES (1) ES2024371A6 (es)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0985680A1 (en) * 1998-09-10 2000-03-15 Hovione Inter Ltd. A process for the purification of roxithromycin
EP1004591A1 (en) * 1998-11-24 2000-05-31 Max India Limited Process for preparing roxithromycin and derivatives thereof
ES2181546A1 (es) * 1999-07-30 2003-02-16 Biochemie Sa Una eritromicina de oxima y un procedimiento para su obtencion.

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0985680A1 (en) * 1998-09-10 2000-03-15 Hovione Inter Ltd. A process for the purification of roxithromycin
US6204368B1 (en) 1998-09-10 2001-03-20 Hovione Inter Ltd. Process for the purification of roxithromycin
EP1004591A1 (en) * 1998-11-24 2000-05-31 Max India Limited Process for preparing roxithromycin and derivatives thereof
ES2181546A1 (es) * 1999-07-30 2003-02-16 Biochemie Sa Una eritromicina de oxima y un procedimiento para su obtencion.

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201