ES2024969A6 - Procedimiento para la obtencion de tetralonas. - Google Patents

Procedimiento para la obtencion de tetralonas.

Info

Publication number
ES2024969A6
ES2024969A6 ES9003308A ES9003308A ES2024969A6 ES 2024969 A6 ES2024969 A6 ES 2024969A6 ES 9003308 A ES9003308 A ES 9003308A ES 9003308 A ES9003308 A ES 9003308A ES 2024969 A6 ES2024969 A6 ES 2024969A6
Authority
ES
Spain
Prior art keywords
group
alkyl
atom
tetralones
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES9003308A
Other languages
English (en)
Inventor
Carmen Almansa
Concepcion Gonzalez
Elena Carceller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Noucor Health SA
Original Assignee
J Uriach y Cia SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by J Uriach y Cia SA filed Critical J Uriach y Cia SA
Priority to ES9003308A priority Critical patent/ES2024969A6/es
Priority to EP19910119718 priority patent/EP0489300A3/en
Priority to US07/801,000 priority patent/US5208246A/en
Priority to CA002056922A priority patent/CA2056922A1/en
Priority to JP3321840A priority patent/JPH07113014B2/ja
Publication of ES2024969A6 publication Critical patent/ES2024969A6/es
Priority to US08/006,852 priority patent/US5272170A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE TETRALONAS DE FORMULA GENERAL I, UTILES COMO REGULADORES DE LA CONTRACCION DE LA MUSCULATURA LISA EN LOS SISTEMAS CARDIOVASCULAR, BRONCOPULMONAR Y DIGESTIVO: EN DONDE RBS1 REPRESENTA UN ATOMO9 DE HALOGENO O UN GRUPO CIANO, NITRO, CSI1-4 ALCOXI; RBS2 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO CSI1-4 ALCOXI; RBS3 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO CSI1-4 ALQUILO Y RBS4 ES CSI1-4 ALQUILO O RBS3 Y RBS4 JUNTOS SON POLIMETILENO; RBS5 ES OH O OCOCHSI3 Y RBS6 HIDROGENO, O BIEN RBS5 Y RBS6 JUNTOS FORMAN UN DOBLE ENLACE; RBS7-RBS8 JUNTOS FORMAN UN GRUPO TRIMETILENO O TETRAMETILENO, LOS CUALES ESTAN OPCIONALMENTE SUSTITUIDOS POR UN GRUPO RBS9 O BIEN RBS7-RBS8 REPRESENTAN UN GRUPO -CH=CH-CH=CH- OPCIONALMENTE SUSTITUIDO POR UN GRUPO RBS10 Y UNO DE CUYOS METINOS PUEDE OPCIONALMENTE REEMPLAZARSE POR UN ATOMO DE NITROGENO; RBS9 ES CSI1-4 ALQUILO O HIDROXILO; RBS10 ES UN ATOMO DE HALOGENO O UN GRUPO CSI1-4 ALQUILO O HIDROXILO Y X ES UN ATOMO DE OXIGENO O AZUFRE,CARACTERIZADO PORQUE SE HACE REACCIONAR LA CORRESPONDIENTE 3,4-EPOXITETRALONA CON UNA AMIDA DE FORMULA RBS7NHCORBS8 EN PRESENCIA DE UNA BASE COMO EL HIDRURO SODICO EN UN DISOLVENTE ADECUADO COMO EL DIMETILSULFOXIDO.
ES9003308A 1990-12-05 1990-12-05 Procedimiento para la obtencion de tetralonas. Expired - Lifetime ES2024969A6 (es)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ES9003308A ES2024969A6 (es) 1990-12-05 1990-12-05 Procedimiento para la obtencion de tetralonas.
EP19910119718 EP0489300A3 (en) 1990-12-05 1991-11-19 New tetralones with pharmacological activity
US07/801,000 US5208246A (en) 1990-12-05 1991-12-02 Tetralones with pharmacological activity
CA002056922A CA2056922A1 (en) 1990-12-05 1991-12-04 Tetralones with pharmacological activity
JP3321840A JPH07113014B2 (ja) 1990-12-05 1991-12-05 薬理活性を有する新規なテトラロン
US08/006,852 US5272170A (en) 1990-12-05 1993-01-22 Tetralones with pharmacological activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9003308A ES2024969A6 (es) 1990-12-05 1990-12-05 Procedimiento para la obtencion de tetralonas.

Publications (1)

Publication Number Publication Date
ES2024969A6 true ES2024969A6 (es) 1992-03-01

Family

ID=8270210

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9003308A Expired - Lifetime ES2024969A6 (es) 1990-12-05 1990-12-05 Procedimiento para la obtencion de tetralonas.

Country Status (1)

Country Link
ES (1) ES2024969A6 (es)

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