ES2019857T3 - Procedimiento para la fabricacion de aminopropanolderivados de compuestos de 3-(2'-hidroxifenil)-1-propanona. - Google Patents

Procedimiento para la fabricacion de aminopropanolderivados de compuestos de 3-(2'-hidroxifenil)-1-propanona.

Info

Publication number
ES2019857T3
ES2019857T3 ES198888110033T ES88110033T ES2019857T3 ES 2019857 T3 ES2019857 T3 ES 2019857T3 ES 198888110033 T ES198888110033 T ES 198888110033T ES 88110033 T ES88110033 T ES 88110033T ES 2019857 T3 ES2019857 T3 ES 2019857T3
Authority
ES
Spain
Prior art keywords
compounds
aminopropanolderivates
propanone
hydroxiphenyl
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888110033T
Other languages
English (en)
Other versions
ES2019857A4 (es
Inventor
Gerd Petrik
Klemens Dr. Schubert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helopharm W Petrik and Co KG
Original Assignee
Helopharm W Petrik and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helopharm W Petrik and Co KG filed Critical Helopharm W Petrik and Co KG
Publication of ES2019857A4 publication Critical patent/ES2019857A4/es
Application granted granted Critical
Publication of ES2019857T3 publication Critical patent/ES2019857T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

SE DESCRIBEN AMINOPROPANOLDERIVADOS DE COMPUESTOS DE 3-(2-HIDROXIFENIL)-1- PROPANONA DE FORMULA (I) Y SUS SALES, PROCEDIMIENTOS PARA SU OBTENCION Y MEDICAMENTOS QUE CONTIENEN ESTOS COMPUESTOS.
ES198888110033T 1987-06-23 1988-06-23 Procedimiento para la fabricacion de aminopropanolderivados de compuestos de 3-(2'-hidroxifenil)-1-propanona. Expired - Lifetime ES2019857T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87109015A EP0296264A1 (de) 1987-06-23 1987-06-23 Aminopropanolderivate von 3-(2-Hydroxyphenyl)-1-propanonderivaten, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
ES2019857A4 ES2019857A4 (es) 1991-07-16
ES2019857T3 true ES2019857T3 (es) 1993-09-16

Family

ID=8197084

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888110033T Expired - Lifetime ES2019857T3 (es) 1987-06-23 1988-06-23 Procedimiento para la fabricacion de aminopropanolderivados de compuestos de 3-(2'-hidroxifenil)-1-propanona.

Country Status (17)

Country Link
EP (1) EP0296264A1 (es)
JP (1) JPS6426540A (es)
KR (1) KR890000400A (es)
AU (1) AU606692B2 (es)
DD (1) DD271701A5 (es)
DE (2) DE3868357D1 (es)
DK (1) DK342188A (es)
ES (1) ES2019857T3 (es)
FI (1) FI883002A (es)
GR (2) GR890300035T1 (es)
HU (1) HU204503B (es)
IL (1) IL86812A (es)
NO (1) NO167974C (es)
PT (1) PT87792B (es)
SU (1) SU1628855A3 (es)
YU (1) YU119988A (es)
ZA (1) ZA884436B (es)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT66890B (fr) * 1976-08-21 1979-01-25 Hexachimie Procede pour la preparation des aryloxy-1 amino-3 propanol-2
DE3226863A1 (de) * 1981-09-18 1983-04-07 Basf Ag, 6700 Ludwigshafen Aminopropanolderivate von 2-hydroxy-ss-phenyl-propiophenonen, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
US4540697A (en) * 1982-09-09 1985-09-10 Basf Aktiengesellschaft Aminopropanol derivatives of 2-hydroxy-β-phenyl-propiophenones, pharmaceutical compositions and use
EP0283540B1 (de) * 1987-03-26 1991-09-18 Helopharm W. Petrik GmbH & Co.KG. Verfahren zur Herstellung von 5-Hydroxydiprafenon und seiner Salze mit Säuren

Also Published As

Publication number Publication date
FI883002A0 (fi) 1988-06-22
HUT51234A (en) 1990-04-28
AU1824188A (en) 1989-01-05
DE3821259A1 (de) 1989-01-05
YU119988A (en) 1989-12-31
HU204503B (en) 1992-01-28
DK342188A (da) 1988-12-24
SU1628855A3 (ru) 1991-02-15
JPS6426540A (en) 1989-01-27
IL86812A0 (en) 1988-11-30
NO167974B (no) 1991-09-23
ZA884436B (en) 1989-03-29
KR890000400A (ko) 1989-03-14
ES2019857A4 (es) 1991-07-16
FI883002A (fi) 1988-12-24
DD271701A5 (de) 1989-09-13
GR3004456T3 (es) 1993-03-31
NO882770D0 (no) 1988-06-22
DE3868357D1 (de) 1992-03-26
IL86812A (en) 1991-12-15
GR890300035T1 (en) 1989-04-12
JPH0320382B2 (es) 1991-03-19
PT87792A (pt) 1988-07-01
NO882770L (no) 1988-12-27
DK342188D0 (da) 1988-06-22
EP0296264A1 (de) 1988-12-28
AU606692B2 (en) 1991-02-14
PT87792B (pt) 1992-10-30
NO167974C (no) 1992-01-02

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