ES2009747T3 - Procedimiento de preparacion de compuestos heterociclicos policiclicos y composicion cosmetica que los contiene. - Google Patents
Procedimiento de preparacion de compuestos heterociclicos policiclicos y composicion cosmetica que los contiene.Info
- Publication number
- ES2009747T3 ES2009747T3 ES198888401062T ES88401062T ES2009747T3 ES 2009747 T3 ES2009747 T3 ES 2009747T3 ES 198888401062 T ES198888401062 T ES 198888401062T ES 88401062 T ES88401062 T ES 88401062T ES 2009747 T3 ES2009747 T3 ES 2009747T3
- Authority
- ES
- Spain
- Prior art keywords
- image
- hydrogen
- procedure
- preparation
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/008—Preparations for oily hair
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/06—Compounds containing nitro groups bound to a carbon skeleton having nitro groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
- C07C205/20—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings
- C07C205/25—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups bound to carbon atoms of six-membered aromatic rings being part of a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/60—Naphthoxazoles; Hydrogenated naphthoxazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/74—Naphthothiophenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Furan Compounds (AREA)
- Saccharide Compounds (AREA)
- Indole Compounds (AREA)
- Steroid Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
COMPUESTOS HETEROCICLICOS POLICICLICOS. ESTOS COMPUESTOS RESPONDEN A LA FORMULA SIGUIENTE (I), EN LA CUAL: N ES 1 O 2; R1 REPRESENTA : (I) UN RADICAL ALQUILO INFERIOR, (II) - CH2OH, O (III) - C - R2; R2 REPRESENTA: (A) UN ATOMO DE HIDROGENO, (B) EL RACICAL O (C) EL RADICAL -O>R3; R3 REPRESENTA UN ATOMO DE HIDROGENO, UN RADICAL ALQUILO C1 - C20, UN RADICAL MONO O POLIHIDROXIALQUILO, UN RADICAL ARILO O ARALQUILO EVENTUALMENTE SUBSTITUIDO (1) O UN RESTO DE UN AZUCAR O AUN ASI REPRESENTA EL RADICAL: SIENDO P= 1, 2 O 3; R'' Y R'''' REPRESENTANDO UN ATOMO DE HIDROGENO, UN RADICAL ALQUILO INFERIOR, UN RADICAL MONOHIDROXIALQUILO O POLIHIDROXIALQUILO, UN RADICAL ARILO EVENTUALMENTE SUBSTITUIDO, UN RESTO DE AMINOACIDO O DE AZUCAR AMINADA O TODAVIA UNA TOMA CONJUNTO FORMANDO UN HETEROCICLO. X REPRESENTA UN ATOMO DE OXIGENO, UN ATOMO DE AZUFRE, SO, SO2 O EL RADICAL - NR4. Y REPRESENTA CR4 O UN ATOMO DE NITROGENO. R4 REPRESENTA UN ATOMO DE HIDROGENO O UN RADICAL ALQUILO INFERIOR. ESTOS DERIVADOS ENCUENTRAN APLICACION EN MEDICINA HUMANA Y VETERINARIZ ESPECIALMENTE EN EL TRATAMIENTO TOPICO Y SISTEMICO DE AFECCIONES DERMATOLOGICAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8706152A FR2614618B1 (fr) | 1987-04-30 | 1987-04-30 | Derives heterocycliques polycycliques, leur procede de preparation et leur utilisation en medecine humaine et veterinaire |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2009747A4 ES2009747A4 (es) | 1989-10-16 |
ES2009747T3 true ES2009747T3 (es) | 1993-05-16 |
Family
ID=9350670
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198888401062T Expired - Lifetime ES2009747T3 (es) | 1987-04-30 | 1988-04-29 | Procedimiento de preparacion de compuestos heterociclicos policiclicos y composicion cosmetica que los contiene. |
Country Status (17)
Country | Link |
---|---|
US (2) | US4874747A (es) |
EP (1) | EP0292348B1 (es) |
JP (1) | JP2579339B2 (es) |
AT (1) | ATE56714T1 (es) |
AU (1) | AU613618B2 (es) |
CA (1) | CA1313372C (es) |
DE (2) | DE292348T1 (es) |
DK (1) | DK175098B1 (es) |
ES (1) | ES2009747T3 (es) |
FI (1) | FI92930C (es) |
FR (1) | FR2614618B1 (es) |
GR (2) | GR890300124T1 (es) |
IE (1) | IE61903B1 (es) |
NO (1) | NO171159C (es) |
NZ (1) | NZ224428A (es) |
PT (1) | PT87358B (es) |
ZA (1) | ZA883079B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5166170A (en) * | 1989-07-03 | 1992-11-24 | Hoechst-Roussel Pharmaceuticals Incorporated | 2-(aminoaryl) indoles and indolines as topical antiinflammatory agents for the treatment of skin disorders |
ES2102195T3 (es) * | 1992-12-28 | 1997-07-16 | Eisai Co Ltd | Derivados heterociclicos de acido carbonico que se fijan en receptores de retinoides. |
US5770383A (en) * | 1994-12-30 | 1998-06-23 | Ligand Pharmaceuticals, Inc. | Tricyclic retinoids, methods for their production and use |
US5770382A (en) * | 1994-12-30 | 1998-06-23 | Ligand Pharmaceuticals, Inc. | Tricyclic retinoids, methods for their production and use |
US5770378A (en) * | 1994-12-30 | 1998-06-23 | Ligand Pharmaceuticals, Inc. | Tricyclic retinoids, methods for their production and use |
ES2190479T3 (es) | 1995-10-06 | 2003-08-01 | Ligand Pharm Inc | Moduladores de rxr selectivos a dimeros y metodos para su uso. |
FR2750426B1 (fr) * | 1996-06-28 | 1998-08-07 | Cird Galderma | Nouveaux composes biaryles heterocycliques et leur utilisation en medecine humaine ou veterinaire ainsi qu'en cosmetique |
EP1093362A1 (en) * | 1998-06-12 | 2001-04-25 | Ligand Pharmaceuticals Incorporated | Treatment of anti-estrogen resistant breast cancer using rxr modulators |
US6566372B1 (en) * | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
HUP0202814A3 (en) * | 1999-08-27 | 2003-11-28 | Ligand Pharmaceuticals Inc San | Androgen receptor modulator compounds and methods for their preparation and pharmaceutical compositions containing them and their use |
WO2001016133A2 (en) | 1999-08-27 | 2001-03-08 | Ligand Pharmaceuticals Incorporated | 8-substituted-6-trifluoromethyl-9-pyrido[3,2-g]quinoline compounds as androgen receptor modulators |
US6593493B1 (en) | 1999-09-14 | 2003-07-15 | Ligand Pharmaceuticals, Inc. | RXR modulators with improved pharmacologic profile |
FR2804323B1 (fr) * | 2000-01-31 | 2006-07-07 | Galderma Res & Dev | Utilisation de composes de type retinoides en tant qu'agents anti-bacteriens |
US9050310B2 (en) * | 2004-06-25 | 2015-06-09 | Minas Theodore Coroneo | Treatment of ocular lesions |
US20060204474A1 (en) * | 2005-02-25 | 2006-09-14 | Coroneo Minas T | Treatment of epithelial layer lesions |
FR2910320B1 (fr) | 2006-12-21 | 2009-02-13 | Galderma Res & Dev S N C Snc | Emulsion comprenant au moins un retinoide et du peroxyde de benzole |
FR2910321B1 (fr) | 2006-12-21 | 2009-07-10 | Galderma Res & Dev S N C Snc | Gel creme comprenant au moins un retinoide et du peroxyde de benzole |
FR2931661B1 (fr) | 2008-05-30 | 2010-07-30 | Galderma Res & Dev | Nouvelles compositions depigmentantes sous forme d'une composition anhydre sans vaseline et sans elastomere comprenant un derive phenolique solubilise et un retinoide. |
US11045441B2 (en) | 2015-10-13 | 2021-06-29 | Wisconsin Alumni Research Foundation | Use of retinoic acid and analogs thereof to treat central neural apneas |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1519474A1 (de) * | 1965-12-27 | 1970-02-19 | Hoechst Ag | Optische Aufhellungsmittel |
CH644116A5 (de) * | 1980-08-21 | 1984-07-13 | Hoffmann La Roche | Imidazolderivate. |
DE3047043A1 (de) * | 1980-12-13 | 1982-07-22 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 2-amino-benzimidazolen |
US4368201A (en) * | 1981-07-20 | 1983-01-11 | Usv Pharmaceutical Corporation | Tetrahydronaphthoxazoles |
LU85544A1 (fr) * | 1984-09-19 | 1986-04-03 | Cird | Derives heterocycliques aromatiques,leur procede de preparation et leur application dans les domaines therapeutique et cosmetique |
US4659360A (en) * | 1984-11-30 | 1987-04-21 | Fmc Corporation | Plant growth and development modification using benzoxazole derivatives |
LU87040A1 (fr) * | 1987-11-04 | 1989-06-14 | Oreal | Esters aromatiques polycycliques d'antibiotiques macrolidiques et lincosamidiques,leur procede de preparation et compositions pharmaceutiques et cosmetiques les contenant |
-
1987
- 1987-04-30 FR FR8706152A patent/FR2614618B1/fr not_active Expired
-
1988
- 1988-04-28 DK DK198802326A patent/DK175098B1/da not_active IP Right Cessation
- 1988-04-28 JP JP63107440A patent/JP2579339B2/ja not_active Expired - Fee Related
- 1988-04-29 NZ NZ224428A patent/NZ224428A/xx unknown
- 1988-04-29 FI FI882030A patent/FI92930C/fi not_active IP Right Cessation
- 1988-04-29 US US07/188,547 patent/US4874747A/en not_active Ceased
- 1988-04-29 PT PT87358A patent/PT87358B/pt not_active IP Right Cessation
- 1988-04-29 AT AT88401062T patent/ATE56714T1/de not_active IP Right Cessation
- 1988-04-29 NO NO881896A patent/NO171159C/no not_active IP Right Cessation
- 1988-04-29 ES ES198888401062T patent/ES2009747T3/es not_active Expired - Lifetime
- 1988-04-29 EP EP88401062A patent/EP0292348B1/fr not_active Expired - Lifetime
- 1988-04-29 AU AU15350/88A patent/AU613618B2/en not_active Ceased
- 1988-04-29 DE DE198888401062T patent/DE292348T1/de active Pending
- 1988-04-29 DE DE8888401062T patent/DE3860640D1/de not_active Expired - Lifetime
- 1988-04-29 CA CA000565554A patent/CA1313372C/fr not_active Expired - Fee Related
- 1988-04-29 IE IE127988A patent/IE61903B1/en not_active IP Right Cessation
- 1988-04-29 ZA ZA883079A patent/ZA883079B/xx unknown
-
1990
- 1990-01-31 GR GR89300124T patent/GR890300124T1/el unknown
- 1990-04-24 US US07/513,970 patent/USRE33533E/en not_active Expired - Lifetime
- 1990-11-20 GR GR90400945T patent/GR3001088T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NO881896L (no) | 1988-10-31 |
JPS63295556A (ja) | 1988-12-01 |
NO171159C (no) | 1993-02-03 |
DK232688D0 (da) | 1988-04-28 |
AU613618B2 (en) | 1991-08-08 |
EP0292348A1 (fr) | 1988-11-23 |
FI92930B (fi) | 1994-10-14 |
IE881279L (en) | 1988-10-30 |
PT87358B (pt) | 1992-08-31 |
FR2614618B1 (fr) | 1989-07-07 |
CA1313372C (fr) | 1993-02-02 |
NO171159B (no) | 1992-10-26 |
ATE56714T1 (de) | 1990-10-15 |
DE292348T1 (de) | 1990-02-08 |
ES2009747A4 (es) | 1989-10-16 |
PT87358A (pt) | 1988-05-01 |
NZ224428A (en) | 1990-05-28 |
DK175098B1 (da) | 2004-06-01 |
GR3001088T3 (en) | 1992-04-17 |
FI882030A (fi) | 1988-10-31 |
FI92930C (fi) | 1995-01-25 |
NO881896D0 (no) | 1988-04-29 |
US4874747A (en) | 1989-10-17 |
AU1535088A (en) | 1988-11-03 |
USRE33533E (en) | 1991-02-05 |
EP0292348B1 (fr) | 1990-09-19 |
DE3860640D1 (de) | 1990-10-25 |
GR890300124T1 (en) | 1990-01-31 |
FI882030A0 (fi) | 1988-04-29 |
DK232688A (da) | 1988-10-31 |
JP2579339B2 (ja) | 1997-02-05 |
FR2614618A1 (fr) | 1988-11-04 |
IE61903B1 (en) | 1994-11-30 |
ZA883079B (en) | 1989-01-25 |
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