ES2007116A6 - Un procedimiento para la preparacion de derivados de hidantoina c-5 etilenicamente instaurados. - Google Patents

Un procedimiento para la preparacion de derivados de hidantoina c-5 etilenicamente instaurados.

Info

Publication number
ES2007116A6
ES2007116A6 ES8702767A ES8702767A ES2007116A6 ES 2007116 A6 ES2007116 A6 ES 2007116A6 ES 8702767 A ES8702767 A ES 8702767A ES 8702767 A ES8702767 A ES 8702767A ES 2007116 A6 ES2007116 A6 ES 2007116A6
Authority
ES
Spain
Prior art keywords
hidantoin
derivatives
procedure
translation
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8702767A
Other languages
English (en)
Inventor
John J Wright
Nicholas A Meanwell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES2007116A6 publication Critical patent/ES2007116A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/96—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE HIDANTOINA C-5 ETILENICAMENTE INSATURADOS DE FORMULA GENERAL (A) Y SUS ISOMEROS GEOMETRICOS Z (CUANDO R'' ESTA EN POSICION CIS CON RESPECTO AL GRUPO N-R2) Y E (CUANDO R'' ESTA EN POSICION TRANS), DONDE R1 Y R2 SON H, ALQUILO O ARALQUILO DE HASTA 10 ATOMOS DE CARBONO Y R'' ES EL RESTO PROCEDENTE DEL DERIVADO CARBONILICO COPULADO. EL PROCEDIMIENTO CONSISTE EN COPULAR UN DERIVADO CARBONILICO TAL COMO UN ALDEHIDO O CETONA ALIFATICA O AROMATICO O UN COMPUESTO DICARBONILICO CON UN HIDANTOIN-5-FOSFONATO DE DIMETILO (I), DONDE R1 Y R2 SON LOS DEFINIDOS ANTES Y R3 ES ALQUILO INFERIOR. LOS DERIVADOS DE HIDANTOINA (A) ASI OBTENIDOS SON UTILES COMO INTERMEDIOS EN LA SINTESIS DE 1,3-DIHIDRO-2H-IMIDAZO-4,5-B-QUINOLIN-2-ONAS, Y COMO INTERMEDIOS EN LA SINTESIS DE FENILALANINA Y DE ACIDO FENILPIRUVICO.
ES8702767A 1986-09-29 1987-09-28 Un procedimiento para la preparacion de derivados de hidantoina c-5 etilenicamente instaurados. Expired ES2007116A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91304186A 1986-09-29 1986-09-29

Publications (1)

Publication Number Publication Date
ES2007116A6 true ES2007116A6 (es) 1989-06-01

Family

ID=25432878

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8702767A Expired ES2007116A6 (es) 1986-09-29 1987-09-28 Un procedimiento para la preparacion de derivados de hidantoina c-5 etilenicamente instaurados.

Country Status (10)

Country Link
KR (1) KR880003919A (es)
AT (1) AT398566B (es)
CA (1) CA1323629C (es)
CH (1) CH676846A5 (es)
ES (1) ES2007116A6 (es)
FI (1) FI874212A (es)
GR (1) GR871506B (es)
HU (2) HU208426B (es)
IT (1) IT1222755B (es)
PT (1) PT85805B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2130192T3 (es) * 1992-07-31 1999-07-01 Hoechst Ag Procedimiento para la preparacion biotecnica de l-tienilalaninas en forma enantiomera pura, partiendo de acidos 2-hidroxi-3-tienil-acrilicos, y su empleo.
AU2003208847A1 (en) 2002-02-21 2003-09-09 Ciba Specialty Chemicals Holding Inc. Lactam-based pigments and the use thereof in the production of coloured plastics or polymeric colour particles
BRPI0512535A (pt) * 2004-06-24 2008-03-25 Incyte Corp compostos de piperidinas n-substituìdas, suas composições e métodos de modulações
WO2011103289A2 (en) * 2010-02-17 2011-08-25 Jasco Pharmaceuticals, LLC Imidazole-2, 4-dione inhibitors of casein kinase 1

Also Published As

Publication number Publication date
PT85805A (en) 1987-10-01
CA1323629C (en) 1993-10-26
IT8722055A0 (it) 1987-09-28
ATA247687A (de) 1994-05-15
AT398566B (de) 1994-12-27
FI874212A (fi) 1988-03-30
GR871506B (en) 1988-01-20
CH676846A5 (en) 1991-03-15
PT85805B (pt) 1990-08-31
HU9201172D0 (en) 1992-07-28
FI874212A0 (fi) 1987-09-25
HUT49858A (en) 1989-11-28
HU208426B (en) 1993-10-28
KR880003919A (ko) 1988-05-31
IT1222755B (it) 1990-09-12

Similar Documents

Publication Publication Date Title
LV11683A (lv) Fenilacetoksitienopiridinu un to starpproduktu - alfa-bromfeniletikskabes atvasinajumu iegusanas panemiens
ES2007116A6 (es) Un procedimiento para la preparacion de derivados de hidantoina c-5 etilenicamente instaurados.
ES8706644A1 (es) Un procedimiento para preparar derivados de dihidropiridazina
KR840000530A (ko) 신규 벤조트리아졸의 제조방법
ES429717A1 (es) Procedimiento de preparacion de nuevos derivados de butira- mida.
IL58311A0 (en) Isomerisation of 3-azabicyvlo (3.1.0)hexane derivatives
IL56507A (en) (trihalomethyl)dimethyloxabicyclohexanone derivatives for the preparation of cis dihalovinyldimethylcyclopropanecarboxylic acids
ES432790A1 (es) Un metodo para producir derivados del acido 2-cloropropioni-co.
ES402471A1 (es) Un procedimiento para la preparacion de derivados de 1-ari-loxi-3-amino-propanol.
KR850001742A (ko) 큐말산 에스테르의 제조방법
CA2129647A1 (en) Process for production of 4,4'-thiobis phenols
ES437041A1 (es) Un procedimiento para preparar derivados de 1-ftalazona.
ES485801A1 (es) Un procedimiento de preparacion de ciclo-1,3,2-oxazafosfo- ril-derivados
DK0546875T3 (da) Hidtil ukendt fremgangsmåde til fremstilling af 20-oxo-17-alpha,21-dihydroxyderivater af pregnan og mellemprodukter dertil
JPS55127331A (en) Preparation of 4-methyl-2,4-bis(p-substituted-oxyphenyl) pent-1-ene
ES2004522A6 (es) Nuevo procedimiento para la preparacion de 4-(6' - metoxi-2'-naftil)butan-2-ona.
GB992797A (en) Improvements in or relating to 6,7-seco-morphinan-6,7-dioic acid derivatives and their preparation
JPS5791991A (en) Preparation of 2-azetidinone derivative
JPS5589354A (en) Preparation of aminothiofluoran compound
ES8606319A1 (es) Un metodo para producir un derivado de acido ascorbico
ES450666A1 (es) Un procedimiento de preparacion de los nuevos derivados del aminometilbenzociclohepteno.
KR920011990A (ko) 벤조페논 유도체의 제조방법
ES8106127A1 (es) Un procedimiento para la preparacion de derivados de ciclo- hexadieno
ES459383A1 (es) Procedimiento para preparar acidos quinolonpropionicos.
ES478656A1 (es) Procedimiento para preparar derivados de isoindolina.

Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2007-09-28