ES2005549A6 - Metodo para preparar una formulacion farmaceutica de liberacion controlada y accion prolongada y metodo de preparar una pluralidad de dosis de dicha formulacion. - Google Patents
Metodo para preparar una formulacion farmaceutica de liberacion controlada y accion prolongada y metodo de preparar una pluralidad de dosis de dicha formulacion.Info
- Publication number
- ES2005549A6 ES2005549A6 ES8700956A ES8700956A ES2005549A6 ES 2005549 A6 ES2005549 A6 ES 2005549A6 ES 8700956 A ES8700956 A ES 8700956A ES 8700956 A ES8700956 A ES 8700956A ES 2005549 A6 ES2005549 A6 ES 2005549A6
- Authority
- ES
- Spain
- Prior art keywords
- uniform
- mixture
- base material
- therapeutic agent
- longacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
METODO PARA PREPARAR UNA FORMULACION FARMACEUTICO DE LIBERACION CONTROLADA Y ACCION PROLONGADA Y METODO DE PREPARAR UNA MULTIPLICIDAD DE DOSIS DE DICHA FORMULACION, QUE COMPRENDE MEZCLAR HOMOGENEAMENTE UN MATERIAL VEHICULO CONSTITUIDO POR AL MENOS UN ETER CELULOSICO CON UN AGENTE TERAPEUTICO, DEJAR EN REPOSO LA MEZCLA FORMADA PARA PERMITIR QUE DICHO AGENTE TERAPEUTICO SE UNA CON DICHO ETER CELULOSICO, Y COMPRIMIR DICHA FORMULACION EN FORMA DE ROTULAS, TABLETAS O SUPOSITORIOS. EL INVENTO SE APLICA A MEDICAMENTOS EN LOS QUE ES NECESARIO LOGRAR NIVELES ESTABLES EN SANGRE DE DIVERSOS AGENTES TERAPEUTICOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/848,702 US4775535A (en) | 1986-04-04 | 1986-04-04 | Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2005549A6 true ES2005549A6 (es) | 1989-03-16 |
Family
ID=25304046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8700956A Expired ES2005549A6 (es) | 1986-04-04 | 1987-04-03 | Metodo para preparar una formulacion farmaceutica de liberacion controlada y accion prolongada y metodo de preparar una pluralidad de dosis de dicha formulacion. |
Country Status (14)
Country | Link |
---|---|
US (1) | US4775535A (es) |
EP (1) | EP0240351B1 (es) |
JP (1) | JPH0751519B2 (es) |
AT (1) | ATE77740T1 (es) |
AU (1) | AU591258B2 (es) |
CA (1) | CA1297409C (es) |
DE (1) | DE3780056T2 (es) |
ES (1) | ES2005549A6 (es) |
GR (1) | GR3005851T3 (es) |
IL (1) | IL82092A (es) |
MX (1) | MX5864A (es) |
PL (1) | PL264984A1 (es) |
YU (1) | YU46312B (es) |
ZA (1) | ZA871818B (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4837031A (en) * | 1987-09-17 | 1989-06-06 | Mallinckrodt, Inc. | Compositions containing ibuprofen |
IT1216570B (it) * | 1988-04-08 | 1990-03-08 | Vectorpharma Int | Composizione farmaceutiche a rilascio controllato e procedimento per la loro preparazione. |
IT1246188B (it) * | 1990-07-27 | 1994-11-16 | Resa Farma | Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute. |
US5225201A (en) * | 1991-08-23 | 1993-07-06 | Minnesota Mining And Manufacturing Company | Salsalate tablet |
US5407686A (en) * | 1991-11-27 | 1995-04-18 | Sidmak Laboratories, Inc. | Sustained release composition for oral administration of active ingredient |
SE9301220D0 (sv) * | 1993-04-14 | 1993-04-14 | Kabi Pharmacia Ab | Manufacturing matrices |
US6676967B1 (en) | 1993-09-20 | 2004-01-13 | Kos Pharmaceuticals, Inc. | Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia |
US6818229B1 (en) | 1993-09-20 | 2004-11-16 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia |
US6080428A (en) | 1993-09-20 | 2000-06-27 | Bova; David J. | Nicotinic acid compositions for treating hyperlipidemia and related methods therefor |
US6746691B2 (en) | 1993-09-20 | 2004-06-08 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
US6129930A (en) | 1993-09-20 | 2000-10-10 | Bova; David J. | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
CA2173818A1 (fr) * | 1996-04-10 | 1997-10-11 | Francois Chouinard | Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose |
GB9611328D0 (en) * | 1996-05-31 | 1996-08-07 | Zeneca Ltd | Pharmaceutical compositions |
US20070185032A1 (en) * | 1996-12-11 | 2007-08-09 | Praecis Pharmaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
US5968895A (en) | 1996-12-11 | 1999-10-19 | Praecis Pharmaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
US7179486B1 (en) | 1997-04-01 | 2007-02-20 | Nostrum Pharmaceuticals, Inc. | Process for preparing sustained release tablets |
US6214381B1 (en) | 1998-09-08 | 2001-04-10 | Effcon, Inc. | Methazolamide composition and method of use |
CA2354057C (en) | 1998-12-11 | 2009-02-10 | Nostrum Pharmaceuticals, Inc. | Sustained release tablet containing hydrocolloid and cellulose ether |
US7130822B1 (en) * | 2000-07-31 | 2006-10-31 | Cognos Incorporated | Budget planning |
US6602911B2 (en) * | 2001-11-05 | 2003-08-05 | Cypress Bioscience, Inc. | Methods of treating fibromyalgia |
US20050112087A1 (en) * | 2003-04-29 | 2005-05-26 | Musso Gary F. | Pharmaceutical formulations for sustained drug delivery |
US20060193825A1 (en) * | 2003-04-29 | 2006-08-31 | Praecis Phamaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
US7994220B2 (en) | 2005-09-28 | 2011-08-09 | Cypress Bioscience, Inc. | Milnacipran for the long-term treatment of fibromyalgia syndrome |
JP2009514884A (ja) * | 2005-11-04 | 2009-04-09 | イーストマン ケミカル カンパニー | 難溶性医薬活性剤の投与のためのカルボキシアルキルセルロースエステル |
KR100591142B1 (ko) * | 2005-11-04 | 2006-06-20 | 지엘팜텍 주식회사 | 파록세틴을 활성물질로 함유하는 장용성 서방형 정제 |
CN107569690A (zh) * | 2012-01-04 | 2018-01-12 | 韦尔斯利医药有限公司 | 用于缓解尿频的延长释放制剂及其使用方法 |
US9980946B1 (en) | 2017-01-25 | 2018-05-29 | Effcon Laboratories, Inc. | Extended release methazolamide formulation |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2980589A (en) * | 1958-09-12 | 1961-04-18 | American Cyanamid Co | Process for producing anhydrous granulation of a medicinally active waterlabile powder |
US3079303A (en) * | 1958-12-11 | 1963-02-26 | Smith Kline French Lab | Basic tablet granulation and process of using same |
US3065143A (en) * | 1960-04-19 | 1962-11-20 | Richardson Merrell Inc | Sustained release tablet |
US3388041A (en) * | 1964-01-27 | 1968-06-11 | Richardson Merrell Inc | High dosage sustained release tablet |
GB1171691A (en) * | 1967-02-24 | 1969-11-26 | Forest Laboratories | Lond-Acting Oral Carrier |
GB1279214A (en) * | 1970-01-22 | 1972-06-28 | Forest Laboratories | Long-acting oral carrier |
US3870790A (en) * | 1970-01-22 | 1975-03-11 | Forest Laboratories | Solid pharmaceutical formulations containing hydroxypropyl methyl cellulose |
US3852421A (en) * | 1970-03-23 | 1974-12-03 | Shinetsu Chemical Co | Excipient and shaped medicaments prepared therewith |
US3957525A (en) * | 1971-04-24 | 1976-05-18 | Dunlop Limited | Road surfacing materials |
GB1405088A (en) * | 1971-06-03 | 1975-09-03 | Mundipharma Ag | Slow release formulation |
CA945899A (en) * | 1971-09-16 | 1974-04-23 | Hans Lowey | Long-acting oral carrier |
BE795766A (fr) * | 1972-02-22 | 1973-08-22 | Lilly Co Eli | Particules de napsylate de propoxyphene retard et procede de fabrication de ces particules |
GB1430684A (en) * | 1972-06-26 | 1976-03-31 | Lowey H | Prolonged release lozenges |
YU43437B (en) * | 1976-05-05 | 1989-08-31 | Lowey Hans | Process for obtaining tablets containing an active component with long lasting effect |
US4226849A (en) * | 1979-06-14 | 1980-10-07 | Forest Laboratories Inc. | Sustained release therapeutic compositions |
US4357469A (en) * | 1979-06-14 | 1982-11-02 | Forest Laboratories, Inc. | Carrier base material for prolonged release therapeutic compositions |
US4259314A (en) * | 1979-12-10 | 1981-03-31 | Hans Lowey | Method and composition for the preparation of controlled long-acting pharmaceuticals |
US4369172A (en) * | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
US4540566A (en) * | 1984-04-02 | 1985-09-10 | Forest Laboratories, Inc. | Prolonged release drug dosage forms based on modified low viscosity grade hydroxypropylmethylcellulose |
-
1986
- 1986-04-04 US US06/848,702 patent/US4775535A/en not_active Expired - Lifetime
-
1987
- 1987-03-12 ZA ZA871818A patent/ZA871818B/xx unknown
- 1987-04-01 CA CA000533564A patent/CA1297409C/en not_active Expired - Lifetime
- 1987-04-01 YU YU56987A patent/YU46312B/sh unknown
- 1987-04-02 AU AU70998/87A patent/AU591258B2/en not_active Expired - Fee Related
- 1987-04-02 EP EP87302881A patent/EP0240351B1/en not_active Expired - Lifetime
- 1987-04-02 AT AT87302881T patent/ATE77740T1/de not_active IP Right Cessation
- 1987-04-02 IL IL82092A patent/IL82092A/xx not_active IP Right Cessation
- 1987-04-02 MX MX586487A patent/MX5864A/es unknown
- 1987-04-02 DE DE8787302881T patent/DE3780056T2/de not_active Expired - Lifetime
- 1987-04-03 PL PL1987264984A patent/PL264984A1/xx unknown
- 1987-04-03 JP JP62082777A patent/JPH0751519B2/ja not_active Expired - Lifetime
- 1987-04-03 ES ES8700956A patent/ES2005549A6/es not_active Expired
-
1992
- 1992-10-01 GR GR920401401T patent/GR3005851T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU591258B2 (en) | 1989-11-30 |
EP0240351A3 (en) | 1988-03-02 |
MX5864A (es) | 1994-01-31 |
EP0240351A2 (en) | 1987-10-07 |
DE3780056T2 (de) | 1992-12-24 |
IL82092A (en) | 1990-09-17 |
IL82092A0 (en) | 1987-10-30 |
YU56987A (en) | 1988-08-31 |
US4775535A (en) | 1988-10-04 |
ATE77740T1 (de) | 1992-07-15 |
EP0240351B1 (en) | 1992-07-01 |
JPH0751519B2 (ja) | 1995-06-05 |
DE3780056D1 (de) | 1992-08-06 |
JPS62294626A (ja) | 1987-12-22 |
CA1297409C (en) | 1992-03-17 |
ZA871818B (en) | 1987-09-02 |
GR3005851T3 (es) | 1993-06-07 |
YU46312B (sh) | 1993-05-28 |
PL264984A1 (en) | 1989-03-20 |
AU7099887A (en) | 1987-10-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20041102 |