YU46312B - Postupak za dobivanje farmaceutske formulacije sa kontrolisanim dugotrajnim oslobadjanjem - Google Patents

Postupak za dobivanje farmaceutske formulacije sa kontrolisanim dugotrajnim oslobadjanjem

Info

Publication number
YU46312B
YU46312B YU56987A YU56987A YU46312B YU 46312 B YU46312 B YU 46312B YU 56987 A YU56987 A YU 56987A YU 56987 A YU56987 A YU 56987A YU 46312 B YU46312 B YU 46312B
Authority
YU
Yugoslavia
Prior art keywords
mixture
base material
therapeutic agent
procedure
tablets
Prior art date
Application number
YU56987A
Other languages
English (en)
Other versions
YU56987A (en
Inventor
H. Lowey
Original Assignee
Hans Lowey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hans Lowey filed Critical Hans Lowey
Priority to SI8710569A priority Critical patent/SI8710569A8/sl
Publication of YU56987A publication Critical patent/YU56987A/xx
Priority to HR930660A priority patent/HRP930660A2/hr
Publication of YU46312B publication Critical patent/YU46312B/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

što se bazni materijal nosača koji obuhvata bar jedan celulozni etar odabran iz grupe koju čine hidroksialkil celuloza i hidroksialkil alkil celuloza meša tokom perioda od 20-40 minuta sa terapeutski aktivnim sredstvom i dobivena uniformna farmaceutska formulacija se ostavi da stoji tokom perioda 2-72 časova bez mešanja radi vezivanja terapeutski aktivnog sredstva za pomenuti celulozni etar, posle čega se sabija pod pritiskom od 6 do 12 kg/cm u oblik podesne dozne jedinice. Prijava sadrži još 3 zavisna zahteva.
YU56987A 1986-04-04 1987-04-01 Postupak za dobivanje farmaceutske formulacije sa kontrolisanim dugotrajnim oslobadjanjem YU46312B (sh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI8710569A SI8710569A8 (sl) 1986-04-04 1987-04-01 Postopek za pridobivanje farmacevtske formulacije s kontroliranim dolgotrajnim sproščanjem
HR930660A HRP930660A2 (en) 1986-04-04 1993-04-01 Method of preparing controlled long-acting pharmaceutical formulations nit dosage form having uniform and comparable bioavailability acteristics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/848,702 US4775535A (en) 1986-04-04 1986-04-04 Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics

Publications (2)

Publication Number Publication Date
YU56987A YU56987A (en) 1988-08-31
YU46312B true YU46312B (sh) 1993-05-28

Family

ID=25304046

Family Applications (1)

Application Number Title Priority Date Filing Date
YU56987A YU46312B (sh) 1986-04-04 1987-04-01 Postupak za dobivanje farmaceutske formulacije sa kontrolisanim dugotrajnim oslobadjanjem

Country Status (14)

Country Link
US (1) US4775535A (sh)
EP (1) EP0240351B1 (sh)
JP (1) JPH0751519B2 (sh)
AT (1) ATE77740T1 (sh)
AU (1) AU591258B2 (sh)
CA (1) CA1297409C (sh)
DE (1) DE3780056T2 (sh)
ES (1) ES2005549A6 (sh)
GR (1) GR3005851T3 (sh)
IL (1) IL82092A (sh)
MX (1) MX5864A (sh)
PL (1) PL264984A1 (sh)
YU (1) YU46312B (sh)
ZA (1) ZA871818B (sh)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
IT1216570B (it) * 1988-04-08 1990-03-08 Vectorpharma Int Composizione farmaceutiche a rilascio controllato e procedimento per la loro preparazione.
IT1246188B (it) * 1990-07-27 1994-11-16 Resa Farma Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute.
US5225201A (en) * 1991-08-23 1993-07-06 Minnesota Mining And Manufacturing Company Salsalate tablet
US5407686A (en) * 1991-11-27 1995-04-18 Sidmak Laboratories, Inc. Sustained release composition for oral administration of active ingredient
SE9301220D0 (sv) * 1993-04-14 1993-04-14 Kabi Pharmacia Ab Manufacturing matrices
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
CA2173818A1 (fr) * 1996-04-10 1997-10-11 Francois Chouinard Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose
GB9611328D0 (en) * 1996-05-31 1996-08-07 Zeneca Ltd Pharmaceutical compositions
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US20070185032A1 (en) * 1996-12-11 2007-08-09 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US7179486B1 (en) 1997-04-01 2007-02-20 Nostrum Pharmaceuticals, Inc. Process for preparing sustained release tablets
US6214381B1 (en) 1998-09-08 2001-04-10 Effcon, Inc. Methazolamide composition and method of use
WO2000033818A1 (en) 1998-12-11 2000-06-15 Nostrum Pharmaceuticals, Inc. Sustained release tablet containing hydrocolloid and cellulose ether
US7130822B1 (en) * 2000-07-31 2006-10-31 Cognos Incorporated Budget planning
US6602911B2 (en) * 2001-11-05 2003-08-05 Cypress Bioscience, Inc. Methods of treating fibromyalgia
US20050112087A1 (en) * 2003-04-29 2005-05-26 Musso Gary F. Pharmaceutical formulations for sustained drug delivery
US20060193825A1 (en) * 2003-04-29 2006-08-31 Praecis Phamaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US7994220B2 (en) 2005-09-28 2011-08-09 Cypress Bioscience, Inc. Milnacipran for the long-term treatment of fibromyalgia syndrome
WO2007056205A2 (en) * 2005-11-04 2007-05-18 Eastman Chemical Company Carboxyalkylcellulose esters for administration of poorly soluble pharmaceutically active agents
KR100591142B1 (ko) * 2005-11-04 2006-06-20 지엘팜텍 주식회사 파록세틴을 활성물질로 함유하는 장용성 서방형 정제
CN103191429A (zh) * 2012-01-04 2013-07-10 韦尔斯利医药有限公司 用于缓解尿频的延长释放制剂及其使用方法
US9980946B1 (en) 2017-01-25 2018-05-29 Effcon Laboratories, Inc. Extended release methazolamide formulation

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2980589A (en) * 1958-09-12 1961-04-18 American Cyanamid Co Process for producing anhydrous granulation of a medicinally active waterlabile powder
US3079303A (en) * 1958-12-11 1963-02-26 Smith Kline French Lab Basic tablet granulation and process of using same
US3065143A (en) * 1960-04-19 1962-11-20 Richardson Merrell Inc Sustained release tablet
US3388041A (en) * 1964-01-27 1968-06-11 Richardson Merrell Inc High dosage sustained release tablet
GB1171691A (en) * 1967-02-24 1969-11-26 Forest Laboratories Lond-Acting Oral Carrier
GB1279214A (en) * 1970-01-22 1972-06-28 Forest Laboratories Long-acting oral carrier
US3870790A (en) * 1970-01-22 1975-03-11 Forest Laboratories Solid pharmaceutical formulations containing hydroxypropyl methyl cellulose
US3852421A (en) * 1970-03-23 1974-12-03 Shinetsu Chemical Co Excipient and shaped medicaments prepared therewith
US3957525A (en) * 1971-04-24 1976-05-18 Dunlop Limited Road surfacing materials
GB1405088A (en) * 1971-06-03 1975-09-03 Mundipharma Ag Slow release formulation
CA945899A (en) * 1971-09-16 1974-04-23 Hans Lowey Long-acting oral carrier
BE795766A (fr) * 1972-02-22 1973-08-22 Lilly Co Eli Particules de napsylate de propoxyphene retard et procede de fabrication de ces particules
GB1430684A (en) * 1972-06-26 1976-03-31 Lowey H Prolonged release lozenges
YU43437B (en) * 1976-05-05 1989-08-31 Lowey Hans Process for obtaining tablets containing an active component with long lasting effect
US4357469A (en) * 1979-06-14 1982-11-02 Forest Laboratories, Inc. Carrier base material for prolonged release therapeutic compositions
US4226849A (en) * 1979-06-14 1980-10-07 Forest Laboratories Inc. Sustained release therapeutic compositions
US4259314A (en) * 1979-12-10 1981-03-31 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4540566A (en) * 1984-04-02 1985-09-10 Forest Laboratories, Inc. Prolonged release drug dosage forms based on modified low viscosity grade hydroxypropylmethylcellulose

Also Published As

Publication number Publication date
MX5864A (es) 1994-01-31
DE3780056T2 (de) 1992-12-24
ZA871818B (en) 1987-09-02
DE3780056D1 (de) 1992-08-06
IL82092A0 (en) 1987-10-30
AU591258B2 (en) 1989-11-30
US4775535A (en) 1988-10-04
EP0240351B1 (en) 1992-07-01
JPS62294626A (ja) 1987-12-22
JPH0751519B2 (ja) 1995-06-05
PL264984A1 (en) 1989-03-20
CA1297409C (en) 1992-03-17
EP0240351A3 (en) 1988-03-02
ES2005549A6 (es) 1989-03-16
ATE77740T1 (de) 1992-07-15
IL82092A (en) 1990-09-17
AU7099887A (en) 1987-10-08
EP0240351A2 (en) 1987-10-07
YU56987A (en) 1988-08-31
GR3005851T3 (sh) 1993-06-07

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