ES2004904A6 - Procedimiento de preparar derivados 5-fluouracilicos - Google Patents
Procedimiento de preparar derivados 5-fluouracilicosInfo
- Publication number
- ES2004904A6 ES2004904A6 ES8700756A ES8700756A ES2004904A6 ES 2004904 A6 ES2004904 A6 ES 2004904A6 ES 8700756 A ES8700756 A ES 8700756A ES 8700756 A ES8700756 A ES 8700756A ES 2004904 A6 ES2004904 A6 ES 2004904A6
- Authority
- ES
- Spain
- Prior art keywords
- cancer
- fluorouracil
- fluorouracil derivatives
- derivative
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GHASVSINZRGABV-UHFFFAOYSA-N Fluorouracil Chemical class FC1=CNC(=O)NC1=O GHASVSINZRGABV-UHFFFAOYSA-N 0.000 title abstract 2
- 230000001093 anti-cancer Effects 0.000 title 1
- WTSKMKRYHATLLL-UHFFFAOYSA-N (6-benzoyloxy-3-cyanopyridin-2-yl) 3-[3-(ethoxymethyl)-5-fluoro-2,6-dioxopyrimidine-1-carbonyl]benzoate Chemical compound O=C1N(COCC)C=C(F)C(=O)N1C(=O)C1=CC=CC(C(=O)OC=2C(=CC=C(OC(=O)C=3C=CC=CC=3)N=2)C#N)=C1 WTSKMKRYHATLLL-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000004849 alkoxymethyl group Chemical group 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17646486 | 1986-07-25 | ||
| JP61181027A JPS63301880A (ja) | 1985-09-03 | 1986-07-30 | ５−フルオロウラシル誘導体 |
| JP62034161A JPS63201127A (ja) | 1987-02-17 | 1987-02-17 | ５−フルオロウラシル誘導体を含有する制癌剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2004904A6 true ES2004904A6 (es) | 1989-02-16 |
Family
ID=27288338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8700756A Expired ES2004904A6 (es) | 1986-07-25 | 1987-03-18 | Procedimiento de preparar derivados 5-fluouracilicos |
Country Status (10)
| Country | Link |
|---|---|
| KR (2) | KR950009857B1 (OSRAM) |
| CH (1) | CH671578A5 (OSRAM) |
| DE (1) | DE3709699C2 (OSRAM) |
| DK (1) | DK169520B1 (OSRAM) |
| ES (1) | ES2004904A6 (OSRAM) |
| FR (1) | FR2605006B1 (OSRAM) |
| GB (1) | GB2192880B (OSRAM) |
| IT (1) | IT1207785B (OSRAM) |
| NL (1) | NL194043C (OSRAM) |
| SE (1) | SE464303B (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4864021A (en) * | 1984-10-30 | 1989-09-05 | Otsuka Pharmaceutical Co., Ltd. | 5-fluorouracil derivatives |
| DE69003670T2 (de) | 1989-01-05 | 1994-01-27 | Otsuka Pharma Co Ltd | Nicht einspritzbares karzinostatisches mittel zur vorbeugung der entzündung durch 5-fluoruracil und verfahren zur behandlung von krebs. |
| KR0172134B1 (ko) * | 1990-07-19 | 1999-02-01 | 오오쓰까 아끼히코 | 고형 제제 |
| PT2495243T (pt) * | 2009-10-27 | 2017-03-13 | Delta-Fly Pharma Inc | Novos derivados de 5-fluoruracilo |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3588036T2 (de) * | 1984-10-30 | 1995-11-16 | Otsuka Pharma Co Ltd | 5-Fluoruracilderivate. |
| JPS61114739A (ja) * | 1984-11-08 | 1986-06-02 | Mitsubishi Rayon Co Ltd | 不飽和カルボン酸製造用触媒の調製法 |
-
1987
- 1987-03-16 DK DK133387A patent/DK169520B1/da not_active IP Right Cessation
- 1987-03-18 ES ES8700756A patent/ES2004904A6/es not_active Expired
- 1987-03-18 SE SE8701118A patent/SE464303B/sv not_active IP Right Cessation
- 1987-03-23 CH CH1091/87A patent/CH671578A5/de not_active IP Right Cessation
- 1987-03-24 GB GB8706972A patent/GB2192880B/en not_active Expired - Fee Related
- 1987-03-25 DE DE3709699A patent/DE3709699C2/de not_active Expired - Fee Related
- 1987-03-30 KR KR1019870002961A patent/KR950009857B1/ko not_active Expired - Fee Related
- 1987-03-30 IT IT8705150A patent/IT1207785B/it active
- 1987-03-30 NL NL8700742A patent/NL194043C/nl not_active IP Right Cessation
- 1987-03-31 FR FR878704500A patent/FR2605006B1/fr not_active Expired - Fee Related
- 1987-07-01 KR KR1019870006895A patent/KR950011394B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IT8705150A0 (it) | 1987-03-30 |
| GB2192880A (en) | 1988-01-27 |
| GB2192880B (en) | 1990-05-09 |
| NL8700742A (nl) | 1988-02-16 |
| KR950011394B1 (ko) | 1995-10-02 |
| DK169520B1 (da) | 1994-11-21 |
| SE464303B (sv) | 1991-04-08 |
| FR2605006A1 (fr) | 1988-04-15 |
| DE3709699A1 (de) | 1988-02-04 |
| DE3709699C2 (de) | 1996-09-05 |
| GB8706972D0 (en) | 1987-04-29 |
| NL194043B (nl) | 2001-01-02 |
| CH671578A5 (OSRAM) | 1989-09-15 |
| IT1207785B (it) | 1989-06-01 |
| SE8701118D0 (sv) | 1987-03-18 |
| KR880001635A (ko) | 1988-04-25 |
| FR2605006B1 (fr) | 1990-01-12 |
| DK133387A (da) | 1988-01-26 |
| KR880001630A (ko) | 1988-04-25 |
| KR950009857B1 (ko) | 1995-08-29 |
| SE8701118L (sv) | 1988-01-26 |
| DK133387D0 (da) | 1987-03-16 |
| NL194043C (nl) | 2001-05-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20060321 |