ES2004904A6 - Anti-cancer 5-fluorouracil derivatives - Google Patents

Anti-cancer 5-fluorouracil derivatives

Info

Publication number
ES2004904A6
ES2004904A6 ES8700756A ES8700756A ES2004904A6 ES 2004904 A6 ES2004904 A6 ES 2004904A6 ES 8700756 A ES8700756 A ES 8700756A ES 8700756 A ES8700756 A ES 8700756A ES 2004904 A6 ES2004904 A6 ES 2004904A6
Authority
ES
Spain
Prior art keywords
cancer
fluorouracil
fluorouracil derivatives
derivative
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8700756A
Other languages
Spanish (es)
Inventor
Setsuro Fujii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61181027A external-priority patent/JPS63301880A/en
Priority claimed from JP62034161A external-priority patent/JPS63201127A/en
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of ES2004904A6 publication Critical patent/ES2004904A6/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Disclosed are a 5-fluorouracil derivative of the formula < IMAGE > wherein R<a> is C1-C6 alkoxymethyl group, particularly the derivative 3-[3-(6-benzoyloxy-3-cyano-2- pyridyloxy-carbonyl)benzoyl]-1-ethoxymethyl-5-fluorouracil, process for preparing the same and use thereof for treating cancer.
ES8700756A 1986-07-25 1987-03-18 Anti-cancer 5-fluorouracil derivatives Expired ES2004904A6 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP17646486 1986-07-25
JP61181027A JPS63301880A (en) 1985-09-03 1986-07-30 5-fluorouracil derivative
JP62034161A JPS63201127A (en) 1987-02-17 1987-02-17 Carcinostatic agent containing 5-fluorouracil derivative

Publications (1)

Publication Number Publication Date
ES2004904A6 true ES2004904A6 (en) 1989-02-16

Family

ID=27288338

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8700756A Expired ES2004904A6 (en) 1986-07-25 1987-03-18 Anti-cancer 5-fluorouracil derivatives

Country Status (10)

Country Link
KR (2) KR950009857B1 (en)
CH (1) CH671578A5 (en)
DE (1) DE3709699C2 (en)
DK (1) DK169520B1 (en)
ES (1) ES2004904A6 (en)
FR (1) FR2605006B1 (en)
GB (1) GB2192880B (en)
IT (1) IT1207785B (en)
NL (1) NL194043C (en)
SE (1) SE464303B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4864021A (en) * 1984-10-30 1989-09-05 Otsuka Pharmaceutical Co., Ltd. 5-fluorouracil derivatives
NL194430C (en) 1989-01-05 2002-04-04 Otsuka Pharma Co Ltd Non-injectable pharmaceutical preparation with anti-cancer effect.
KR0172134B1 (en) * 1990-07-19 1999-02-01 오오쓰까 아끼히코 Solid preparation
ES2619937T3 (en) * 2009-10-27 2017-06-27 Delta-Fly Pharma, Inc. New 5-fluorouracil derivative

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK174238B1 (en) * 1984-10-30 2002-10-07 Otsuka Pharma Co Ltd 5-Fluorouracil derivatives, their preparation and drugs containing such compounds
JPS61114739A (en) * 1984-11-08 1986-06-02 Mitsubishi Rayon Co Ltd Preparation of catalyst for preparing unsaturated carboxylic acid

Also Published As

Publication number Publication date
DK133387A (en) 1988-01-26
GB2192880B (en) 1990-05-09
NL194043C (en) 2001-05-03
IT8705150A0 (en) 1987-03-30
DK169520B1 (en) 1994-11-21
NL8700742A (en) 1988-02-16
KR880001635A (en) 1988-04-25
DE3709699A1 (en) 1988-02-04
CH671578A5 (en) 1989-09-15
DK133387D0 (en) 1987-03-16
NL194043B (en) 2001-01-02
GB2192880A (en) 1988-01-27
IT1207785B (en) 1989-06-01
FR2605006B1 (en) 1990-01-12
KR880001630A (en) 1988-04-25
KR950011394B1 (en) 1995-10-02
FR2605006A1 (en) 1988-04-15
GB8706972D0 (en) 1987-04-29
SE8701118L (en) 1988-01-26
KR950009857B1 (en) 1995-08-29
DE3709699C2 (en) 1996-09-05
SE8701118D0 (en) 1987-03-18
SE464303B (en) 1991-04-08

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20060321